degS:Quickview

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Standard Name

degS

Gene Synonym(s)

ECK3224, b3235, JW3204, hhoB, htrH[1], htrH

Product Desc.

inner membrane serine protease required for the extracytoplasmic stress response mediated by sigmaE[2]; serine endoprotease, periplasmic[3]

Serine protease, degrades periplasmic RseA, activating RpoE; multicopy suppressor of prc; periplasmic stress sensor for unfolded or misfolded OMPs[4]

Product Synonyms(s)

serine endoprotease, periplasmic[1], B3235[2][1], HtrH[2][1], HhoB[2][1], DegS[2][1] , ECK3224, hhoB, htrH, JW3204, b3235

Function from GO

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Knock-Out Phenotype
Regulation/Expression

transcription unit(s): degQ[2]

Regulation/Activity
Quick Links

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Notes

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degS is an essential gene. DegS may be anchored to the inner membrane. Mutants have elevated OM vesiculation (McBroom, 2006).[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.