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Standard Name


Gene Synonym(s)

ECK0567, b0575, JW0564, ybdE, agrA[1][2], silA

Product Desc.


Component of Copper Transporting Efflux System[3]

Silver and copper efflux, membrane transporter; overexpression confers low level fosfomycin resistance; confers copper and silver resistance[4]

Product Synonyms(s)

copper/silver efflux system, membrane component[1], B0575[2][1], CusA[2][1], YbdE[2][1], AgrA[2][1] , ECK0567, JW0564, silA, ybdE, b0575

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): cusCFBA[2], ylcBCD-ybdE

Quick Links

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cusA is in the cusCFBA Cu and Ag efflux operon regulated by Cu and Ag.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.