chbR:Quickview
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Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
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Standard Name |
chbR |
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Gene Synonym(s) |
ECK1733, b1735, JW1724, celD[1], celD |
Product Desc. |
ChbR transcriptional regulator[2]; ChbR transcriptional dual regulator[3] Repressor, chb operon for N,N'-diacetylchitobiose utilization; AraC family [4] |
Product Synonyms(s) |
DNA-binding transcriptional dual regulator[1], B1735[2][1], ChbR[2][1], CelD[2][1] , celD, ECK1733, JW1724, b1735 |
Function from GO |
<GO_nr /> |
Knock-Out Phenotype |
Chitobiose negative and Cellobiose negative |
Regulation/Expression | |
Regulation/Activity |
Repressor in the absence of inducer and activator in the presence of inducer. |
Quick Links | |
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Notes
ChbR was initially reported as a repressor of the chb operon. However later work showed that this protein is an activator as well as the repressor of the chb operon. The mutations in the chbR have also been reported to confer Cel+ phenotype to E. coli.
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Kachroo, AH et al. (2007) Mutations that alter the regulation of the chb operon of Escherichia coli allow utilization of cellobiose. Mol. Microbiol. 66 1382-95 PubMed
- ↑ Plumbridge, J & Pellegrini, O (2004) Expression of the chitobiose operon of Escherichia coli is regulated by three transcription factors: NagC, ChbR and CAP. Mol. Microbiol. 52 437-49 PubMed
- ↑ Keyhani, NO & Roseman, S (1997) Wild-type Escherichia coli grows on the chitin disaccharide, N,N'-diacetylchitobiose, by expressing the cel operon. Proc. Natl. Acad. Sci. U.S.A. 94 14367-71 PubMed