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References Suggestions


Standard Name


Gene Synonym(s)

ECK3046, b3056, JW3028[1], JW3028

Product Desc.

tRNA nucleotidyltransferase[2][3]

tRNA nucleotidyltransferase, repairs terminal CCA of tRNAs[4]

Product Synonyms(s)

fused tRNA nucleotidyl transferase[1], 2'3'-cyclic phosphodiesterase and 2'nucleotidase and phosphatase[1], B3056[2][1], CCA-adding enzyme, ECK3046, JW3028, b3056

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): htrG-cca[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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The CCA C-terminal HD domain has Ni(2+)-dependent phosphatase activity toward pyrophosphate, canonical 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP. It also has metal-independent phosphodiesterase activity toward 2',3'-cAMP, -cGMP, and -cCMP.[4]


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  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.