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References Suggestions


Standard Name


Gene Synonym(s)

ECK2075, b2079, JW2064[1], JW2064

Product Desc.

DNA-binding response regulator in two-component regulatory system with BaeS[1]

Response regulator for mdtABCD, acrD and spy[2]

Product Synonyms(s)

B2079, ECK2075, JW2064, b2079

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): mdtABCD-baeSR[3], baeSR[3]

Quick Links

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Confers novobiocin and deoxycholate resistance via activation of mdtABCD and acrD transcription. BaeRS multicopy suppresses envZ and phoR/creC mutations. Spy is induced by envelope stress, dependent on both CpxR and BaeSR.[2]


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  1. 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  3. 3.0 3.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7