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References Suggestions


Standard Name


Gene Synonym(s)

ECK4125, b4131, JW4092[1], JW4092

Product Desc.


Component of lysine decarboxylase[2][3]

Lysine decarboxylase, acid-inducible; decameric[4]

Product Synonyms(s)

lysine decarboxylase 1[1], B4131[2][1], CadA[2][1] , ECK4125, JW4092, b4131

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): cadBA[2]

Quick Links

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Induction of the cadAB operon under acidic conditions and in the presence of lycine neutralized extracellualr environment and enabled production of CO(2); production of cadaverine and aminopropylcadaverine instead of putrescine and spermidine also resulted. cadAB operon induction also generated a proton motive force. Lack of cadBA opereon induction results in an increase in speF-potE operon expression. CadA is required for full pathogenicity of Salmonella and Vibrio. CadA and RavA ATPase form a complex.[4]


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  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.