rdoA:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

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Standard Name

rdoA

Gene Synonym(s)

yihE, ECK3851, b3859, JW3831, orfA[1][2], orfA

Product Desc.

cytoplasmic protein of low abundance[2]; serine/threonine protein kinase[3]

Thr/Ser kinase implicated in Cpx stress response[4]

Product Synonyms(s)

predicted kinase[1], B3859[2][1], OrfA[2][1], RdoA[2][1], YihE[2][1] , ECK3851, JW3831, orfA, yihE, b3859

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): rdoA-dsbA[2], yihE-dsbA

Regulation/Activity
Quick Links

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Notes

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rdoA is required for long-term cell survival and for the expression of surface appendages (Zheng, 2007). The RdoA protein kinase may be involved in the regulation of the extracytoplasmic stress response in E. coli (Zheng, 2007). RdoA was identified as a weakly expressed 39 kDa cytoplasmic protein in E. coli (Belin, 1994). The rdoA gene is involved in viulence of Shigella flexerneri via its regulatory role of the gal operon during LPS synthesis; mutations in rdoA result in altered LPS structure (Edwards-Jones, 2004). RdoA is involved in relaying cpx-induced signals in Salmonella (Suntharalingam, 2003). rdoA is in an operon with dsbA in E. coli, but not directly involved in disulfide bond formation (Belin, 1994). A transcript array in Shigella shows major changes in a rdoA deletion strain (li, 2001). Cpx regulon.[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.