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Standard Name


Gene Synonym(s)

gidA, ECK3734, b3741, JW3719, trmF[1][2], mnmB, trmF

Product Desc.

protein involved in a tRNA modification pathway[3][2]

5-methylaminomethyl-2-thiouridine modification at tRNA U34; cmnm(5) addition to tRNA-s(2)U34, forming (with prior MnmE action) tRNA-cmnm(5)s(2)U34, an intermediate in mnm(5)s(2)U34 synthesis; contains essential FAD-binding site (Yim, 2006)[4]

Product Synonyms(s)

glucose-inhibited cell-division protein[1], B3741[3][1], GidA[3][1], MnmG[2][1] , ECK3734, gidA, JW3719, mnmB, trmF, b3741

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): gidB[3]

Quick Links

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mnmG function is based on genetic experiments showing tht it is in the same pathway as mnmE and that mnmE is epistatic to mnmG. The basis of the mnmG(GidA) glucose-inhibited division phenotype is unknown. The proposal (Bregeon, 2001) that mnmG(gidA) and trmF are allelic is based on similar phenotypes and map positions. MnmG(GidA) may have additional functions in the modification of RNA or DNA. MnmG(GidA) and MnmE form a heterotetrameric complex (Yim, 2006).[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 3.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.