From EcoliWiki
(Redirected from b3011)
Jump to: navigation, search

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions


Standard Name


Gene Synonym(s)

ECK3003, b3011, JW2978[1], JW2978

Product Desc.

NADP-dependent alcohol dehydrogenase[2][3]

Aldehyde reductase, protects against lipid oxidation; NADPH-dependent; contains Zn; homodimer[4]

Product Synonyms(s)

alcohol dehydrogenase, NAD(P)-dependent[1], B3011[2][1], YqhD[2][1] , ECK3003, JW2978, b3011

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): yqhD[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

</protect> See Help:Quickview for help with entering information in the Quickview table. <protect></protect>


[back to top]

AFMB Structural Genomics target No. 57 (http://afmb.cnrs-mrs.fr/article171.html). HT_Cmplx40_Cyt: YbgI+YqhD. YqhD is induced under conditions that favor lipid oxidation; overexpression increases resistance to paraquat, hydrogen peroxide and the lipid peroxidation-derived aldehydes butanaldehyde, propanaldehyde, acrolein and malondialdehyde; yqhD mutants are senstive to paraquat and hydrogen peroxide (Perez, 2008). YqhD catalyzes the NADPH-dependent reduction of acetaldehyde, malondialdehyde, propanaldehyde, butanaldehyde and acrolein in vitro (Perez, 2008). YqhD was reported to have no aldehyde dehydrogenase activity and to have in vitro alcohol dehydrogenase activity with a preference for alcohols longer than C3(Sulzenbacher , 2004), however these results are contradicted by Perez (2009).[4]


[back to top]

  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.