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References Suggestions


Standard Name


Gene Synonym(s)

ECK2592, b2594, JW2576, sfhB, yfiI, G7351[1][2]

Product Desc.

23S rRNA pseudouridine synthase[2][3]

23S rRNA pseudouridine synthase; specific to U1911, U1915, and U1917; mutation supresses ftsH(Ts) mutants; null mutants grow very poorly[4]

Product Synonyms(s)

23S rRNA pseudouridine synthase[1], B2594[2][1], YfiI[2][1], RluD[2][1], SfhB[2][1] , ECK2592, JW2576, sfhB, yfiI, b2594

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): yfiH[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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The very poor growth of rluD mutants can be suppressed by a point mutation in prfB and a role in translation termination for the 23S rRNA helix 69 pseudouridines has been demonstrated (Ejby, 2007).[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.