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References Suggestions


Standard Name


Gene Synonym(s)

ECK2557, b2559, JW2543, yfhC[1], yfhC

Product Desc.

TadA; of tRNA specific adenosine deaminase[2][3];

Component of tRNA-specific adenosine deaminase[3]

A34-tRNA adenosine deaminase; point mutation confers resistance to HokC(Gef)-mediated cell killing; essential gene; homodimeric[4]

Product Synonyms(s)

tRNA-specific adenosine deaminase[1], TadA[2][1], YfhC[2][1], B2559[2][1] , ECK2557, JW2543, yfhC, b2559

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): tadA[2]

Quick Links

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Previously reported non-essential nature was mistakenly based on an insertion that removed the last 17 aa, but the truncated enzyme is active. Three possible start sites annotated in various orthologs: -11, +1, and +12; alignment results ambiguous; +1 chosen due to best RBS.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.