acrD:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
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Standard Name

acrD

Gene Synonym(s)

ECK2465, b2470, JW2454, yffA, arcD'[1][2]

Product Desc.

AcrD[2][3];

Component of AcrAD-TolC Multidrug Efflux Transport System[3]

Aminoglycoside efflux pump; RND-type transporter[4]

Product Synonyms(s)

aminoglycoside/multidrug efflux system[1], B2470[2][1], YffA[2][1], AcrD[2][1] , ECK2465, JW2454, yffA, b2470

Function from GO

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Knock-Out Phenotype
Regulation/Expression

transcription unit(s): acrD[2]

Regulation/Activity
Quick Links

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Notes

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acrD mutation confers increased sensitivity to aminoglycosides. acrD is paralogous to acrB. EvgAS regulon.[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.