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References Suggestions


Standard Name


Gene Synonym(s)

yecO, ECK1871, b1870, JW1859[1][2], JW1859

Product Desc.

putative methyltransferase[3]; predicted methyltransferase[2]

Probable tRNA(mcmo5U34)methyltransferase, SAM-dependent[4]

Product Synonyms(s)

predicted methyltransferase[1], YecO[3][1], B1870[3][1], CmoA[2][1], CmoB[2][1] , ECK1871, JW1859, yecO, b1870

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): yecN[3]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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CmoA catalyzes an intermediate step(s) in tRNA(cmo5U34) and tRNA(mcmo5U34) synthesis that forms uridine-5-oxyacetic acid (cmo5U) and uridine-5-oxyacetic acid methyl ester (mcmo5U) in tRNA. The cmoA ortholog is functionally characterized in S. typhimurium. YecO is paralogous to YgdE and FtsJ. otherPDB (H. influenzae): 1IM8. Modeling of 1IM8 suggests substrate might be a benzoic acid derivative, possibly consistent with a chorismic acid requirement for the synthesis of cmo(5)U34.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 3.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.