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Standard Name


Gene Synonym(s)

ECK1532, b1539, JW1532[1], JW1532

Product Desc.

3-hydroxy acid dehydrogenase[2][3];

Component of 3-hydroxy acid dehydrogenase[3]

L-allo-threonine dehydrogenase, NADP+-dependent; other substrates include L-serine, D-serine, D-threonine and 3-hydroxyisobutyrate[4]

Product Synonyms(s)

L-allo-threonine dehydrogenase, NAD(P)-binding[1], B1539[2][1], YdfG[2][1] , ECK1532, JW1532, b1539

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): ydfG[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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The product of the oxidation of the 3-hydroxyl group of L-allo-threonine is aminoacetone, via spontaneous decarboxylation of the primary reaction product L-2-amino-3-ketobutyrate. Downregulated by beryllium.[4]


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  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.