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References Suggestions


Standard Name


Gene Synonym(s)

ECK0832, b0842, JW0826, cmlA, mdfA, cmr[1], cmr

Product Desc.

MdfA/MdfA MFS multidrug transporter[2][3]

Transmembrane multidrug/chloramphenicol efflux transporter; confers alkaline pH tolerence[4]

Product Synonyms(s)

multidrug efflux system protein[1], B0842[2][1], CmlA[2][1], MdfA[2][1], Cmr[2][1] , cmlA, cmr, ECK0832, JW0826, b0842

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): mdfA[2], mdfA

Quick Links


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Major Facilitator Superfamily (MFS). C-terminal domain is not required for function of Cmr.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.