iraP:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
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Standard Name

iraP

Gene Synonym(s)

yaiB, ECK0377, b0382, JW0373[1][2], JW0373

Product Desc.

anti-adaptor protein for σS stabilization[2][3]

RpoS stabilzer during Pi starvation, anti-RssB factor[4]

Product Synonyms(s)

predicted protein[1], B0382[2][1], YaiB[2][1], IraP[2][1] , ECK0377, JW0373, yaiB, b0382

Function from GO

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Knock-Out Phenotype
Regulation/Expression

transcription unit(s): yaiB[2]

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Notes

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IraP interferes with RssB, ClpXP-dependent degradation of RpoS by interacting directly with RssB.[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.

[1] [2]

[3]

  1. Bougdour, A et al. (2006) Modulating RssB activity: IraP, a novel regulator of sigma(S) stability in Escherichia coli. Genes Dev. 20 884-97 PubMed
  2. Tu, X et al. (2006) The PhoP/PhoQ two-component system stabilizes the alternative sigma factor RpoS in Salmonella enterica. Proc. Natl. Acad. Sci. U.S.A. 103 13503-8 PubMed
  3. Bougdour, A & Gottesman, S (2007) ppGpp regulation of RpoS degradation via anti-adaptor protein IraP. Proc. Natl. Acad. Sci. U.S.A. 104 12896-901 PubMed