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References Suggestions


Standard Name


Gene Synonym(s)

pfs, ECK0158, b0159, JW0155, yadA[1][2], mtnN, yadA

Product Desc.

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase[2][3];

Component of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase[3]

5'-Methylthioadenosine nucleosidase; S-adenosylhomocysteine and 5'-deoxyadenosine are also substrates[4]

Product Synonyms(s)

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase[1], B0159[2][1], Mtn[2][1], YadA[2][1], Pfs[2][1] , ECK0158, JW0155, mtnN, pfs, yadA, b0159

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): yadS[2]

Quick Links

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Mutants accumulate 5'-deoxyadenosine and have impaired biotin synthase activity. Required for AI-2 autoinducer synthesis in Salmonella and P. gingivalis.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.