Category:Complex:PDXH-CPLX
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About
Comments (originally from EcoCyc[1][2]) The pdxH gene codes for a monofunctional flavoprotein enzyme that can accept either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) as substrates. The PNP/PMP oxidase is a key committed enzyme in the biosynthesis of the coenzyme pyridoxal 5'-phosphate. The enzyme also functions in the salvage pathway. Since the oxidase uses molecular oxygen, there may be a second pathway in anaerobically growing E. coli. [3][4]
References
- ↑ EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ Zhao, G & Winkler, ME (1995) Kinetic limitation and cellular amount of pyridoxine (pyridoxamine) 5'-phosphate oxidase of Escherichia coli K-12. J. Bacteriol. 177 883-91 PubMed
- ↑ Yang, Y et al. (1998) Identification and function of the pdxY gene, which encodes a novel pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate biosynthesis in Escherichia coli K-12. J. Bacteriol. 180 1814-21 PubMed
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