Category:Complex:AHAS

From EcoliWiki
(Redirected from AHAS)
Jump to: navigation, search

About

Comments (originally from EcoCyc[1][2]) Acetohydroxyacid synthase II (AHAS II) catalyzes the biosynthesis of α-aceto-α-hydroxybutyrate and α-acetolactate. It is not found in E. coli K-12 due to a mutation in ilvG.

AHAS II is a bifunctional enzyme that catalyzes the biosynthesis of α-aceto-α-hydroxybutyrate for the isoleucine pathway and of α-acetolactate for the valine pathway [3][4][5][4] for more information.


References

  1. EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  2. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. Dailey, FE & Cronan, JE Jr (1986) Acetohydroxy acid synthase I, a required enzyme for isoleucine and valine biosynthesis in Escherichia coli K-12 during growth on acetate as the sole carbon source. J. Bacteriol. 165 453-60 PubMed
  4. 4.0 4.1 Hill, CM et al. (1997) Purification of Escherichia coli acetohydroxyacid synthase isoenzyme II and reconstitution of active enzyme from its individual pure subunits. Biochem. J. 327 ( Pt 3) 891-8 PubMed
  5. Lu, MF & Umbarger, HE (1987) Effects of deletion and insertion mutations in the ilvM gene of Escherichia coli. J. Bacteriol. 169 600-4 PubMed

Pages in category "Complex:AHAS"

This category contains only the following page.