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Browse and analyze data from Al Mamun et al. (Science 2012) Identity and Function of a Large Gene Network Underlying Mutagenic Repair of DNA Breaks 338:1344-1348

This dataset of 93 genes was constructed by screening E. coli for mutants deficient in mutagenic repair of DNA breaks under stress, followed by secondary screens for genes that participate in activation of stress responses. This study identifies a network of genes involved in stress-induced mutagenesis (the SIM Network). This data browser allows you to examine the classification of SIM network genes and explore the data from different assays on individual network genes. You can also download excel versions of the supplemental tables from the paper.

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SIM Network Genes Upstream of rpoS

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Excel versions of supplemental tables:

ClassSIM network genes upstream of rpoS
MetabolismapaH
Chaperones and proteasescspC
Electron transfercyoA
Electron transfercyoD
Electron transferfre
RegulatorsglnK
RegulatorshdfR
Electron transferhemL
Chaperones and proteaseshfq
Electron transferhscB
Electron transfermdh
RegulatorsmetJ
Electron transfernuoC
Electron transfernuoG
Electron transfernuoH
Electron transfernuoJ
Electron transfernuoK
Electron transfernuoL
Electron transferpgi
MetabolismrbsK
RegulatorsrpoS
Electron transfersdhB
Electron transfersdhD
MetabolismspeD
MetabolismspeE
Electron transferubiA
Electron transferubiD
Electron transferubiE
Electron transferubiH
Electron transferubiX
UnknownyifE