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rpoB:Gene

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Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments

public

rpoBE813K

E813K

Disrupts the enzyme's active center

seeded from UniProt:P0A8V2

public

rpoB352

CGSC:5386

public

rpoB308

CGSC:5088

public

rpoB70

CGSC:5697

public

rpoB302

CGSC:5724

public

rpoB301

CGSC:5967

public

rpoB79

CGSC:6644

public

rpoB180

CGSC:6647

public

rpoB318

CGSC:6800

public

rpoB316

CGSC:7059

public

rpoB324(rifR)

rifampicin resistant

CGSC:7075

public

rpoB331(rifR)

rifampicin resistant

CGSC:8722

public

rpoB306

CGSC:9150

public

rpoB2(ts)

temperature sensitive

PMID:8113195

CGSC:9774

public

rpoB7(ts, rifR)

"temperature-sensitive, rifampicin resistant"

CGSC:9775

public

rpoB3(rifR)

rifampicin resistant

CGSC:10384

public

rpoB0(rifR)

rifampicin resistant

CGSC:10521

public

rpoB342

CGSC:10832

public

rpoB303

CGSC:11987

public

rpoB23(rifR)

rifampicin resistant

CGSC:14556

public

rpoB307

CGSC:16669

public

rpoB317

CGSC:17095

public

rpoB2066

PMID:7009579

CGSC:67259

public

rpoB2069

PMID:7009579

CGSC:67261

public

rpoB2067

PMID:7009579

CGSC:67262

public

rpoB2068

PMID:7009579

CGSC:67265

public

rpoB*35

Sensitivity to

decreases sensitivity to bicyclomycin

PMID:21183718

fig. 2; the rpoB*35 allele is described in [1]

public

rpoB361 ridB1

Dependence

Mutant is dependent on rifampicin. with the condition its grown below 42C in rich medium.

PMID:6757665

strain: PB61

table 3 and figure 1

public

stv-72

Resistant to

Resistant to Streptovaricin

PMID:4387741

Strain: KY5102

Figure 1.

The paper also describes other alleles with the same phenotype.

public

mbrD7

Resistant to

Resistance to camphor, other mutants with similar phenotypes are described.

PMID:2176633

PMID:1925019

Table 2 and Table 1

public

rpoB in strain K100R3

Resistant to

Rfampin resistance

PMID:4879326

Strain: K1100R3

Table 1

public

rpoB 3445

AA residue affected 507-687

Resistant to

Resistant to rifampicin

PMID:3050121

Several strain were described in table 7

Evidence in table 7

public

rpoB in strain KY1343

Resistant to

Resistance to Streptolydigin. in vivo.

PMID:4571524

Strains: KY1343, KY1345, KY1360, KY1361, KY1348

Table 2 shows resistance phenotype and other strains with similar mutations.

public

rpoB in strain PA6075

Resistant to

Resistant to Streptolydigin

PMID:4897821

Strain: PA6075

Figure 1

public

rpoB706 dnaA1

Growth Phenotype

DnaA1 Mutant is unable to grow at 42.5C, mutation in rpoB suppresses thermosensitivity allowing the strain to grow at 42.5C.

PMID:400782

Experimental Strain: EC8


  1. ↑ (could not retreive XML for PMID:xxxx from NCBI. ) could not retreive XML for PMID:xxxx from NCBI. could not retreive XML for PMID:xxxx from NCBI. could not retreive XML for PMID:xxxx from NCBI. could not retreive XML for PMID:xxxx from NCBI. PubMed


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