TableEdit

Jump to: navigation, search

aspC:Gene

You don't have sufficient rights on this wiki to edit tables. Perhaps you need to log in. Changes you make in the Table editor will not be saved back to the wiki

See Help for Help on this wiki. See the documentation for how to use the table editor

See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments

public

aspCH133N

H133N

Auxotrophies

Decreases to 60% in maximum rate of the overall reactions in both directions

seeded from UniProt:P00509

public

aspCR374F,Y

R374F,Y

Auxotrophies

Second-order rate constants are reduced by >5 orders of magnitude

seeded from UniProt:P00509

public

aspCH133A

H133A

Auxotrophies

Slight increase in maximum velocity of the overall transamination reaction between aspartate and 2-oxoglutarate

seeded from UniProt:P00509

public

aspCY65F,S

Y65F,S

Auxotrophies

Slight changes in activity

seeded from UniProt:P00509

public

ΔaspC (Keio:JW0911)

deletion

deletion

Auxotrophies

Still Asp+. Mutations in aspC, tyrB, and ilvE are required before E. coli K-12 becomes auxotrophic for aspartate.[1]

PMID:16738554

Shigen

CGSC8924[2]

public

aspC::Tn5KAN-2 (FB20252)

Insertion at nt 615 in Minus orientation

Auxotrophies

PMID:15262929

E. coli Genome Project:FB20252

does not contain pKD46

public

aspC13

Auxotrophies

PMID:15983

CGSC:5110

public

aspC25

Auxotrophies

CGSC:5114

public

ΔaspC745::kan

deletion

deletion

Auxotrophies

PMID:16738554

CGSC:100112


  1. Gelfand, DH & Steinberg, RA (1977) Escherichia coli mutants deficient in the aspartate and aromatic amino acid aminotransferases. J. Bacteriol. 130 429-40 PubMed
  2. CGSC: The Coli Genetics Stock Center



Cancel