The Comprehensive Antibiotic Resistance Database - Revision history

Agmcarthur: Table edited by Agmcarthur via TableEdit

2011-10-13T17:17:06Z

Table edited by Agmcarthur via TableEdit

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	!align=left {{table heading style}} \|Who:		!align=left {{table heading style}} \|Who:
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			Gerry D. Wright, McMaster University
			Fazmin Nizam, McMaster University
			Nicholas Waglechner, McMaster University
			Andrew G. McArthur, AGM Bioinformatics Consulting
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	!align=left {{table heading style}} \|Updates:		!align=left {{table heading style}} \|Updates:

Agmcarthur: Table edited by Agmcarthur via TableEdit

2011-10-13T17:15:08Z

Table edited by Agmcarthur via TableEdit

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	!align=left {{table heading style}} \|Link/URL:		!align=left {{table heading style}} \|Link/URL:
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			http://arpcard.mcmaster.ca
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	!align=left {{table heading style}} \|What:		!align=left {{table heading style}} \|What:
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			A bioinformatic database of resistance genes, their products and associated phenotypes.
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	!align=left {{table heading style}} \|Who:		!align=left {{table heading style}} \|Who:
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	!align=left {{table heading style}} \|Updates:		!align=left {{table heading style}} \|Updates:
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	!align=left {{table heading style}} \|Upcoming events:		!align=left {{table heading style}} \|Upcoming events:
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	!align=left {{table heading style}} \|Web Services:		!align=left {{table heading style}} \|Web Services:
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Agmcarthur: /* Content */

2011-10-13T17:12:01Z

Content

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	==Content==		==Content==
			At the genome and plasmid level, CARD focuses upon MRSA and Acinetobacter baumannii, plus a handful of examples from a number of other bacterial species. This has been supplmented with an extensive set of reference genes involved antibiotic resistance from a variety of organisms, genomes, and plasmids. CARD's overall emphasis is primarily upon molecular data and development of an Antibiotic Resistance Ontology to guide annotation of resistance mechanisms, determinants, and targets. This reference information is used to power new annotation tools, such as our Resistance Gene Identifier for annotation of whole genomes or genome assemblies.

	==Using {{PAGENAME}} ==		==Using {{PAGENAME}} ==

Agmcarthur: /* Technology */

2011-10-13T17:10:43Z

Technology

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	==Technology==		==Technology==
			CARD is Generic Model Organism Database (GMOD), using the Chado schema and GBrowse2.
	===Web Services/API===		===Web Services/API===

Agmcarthur: /* Other sites with related content {{HelpIcon|Help:Databases}} */

2011-10-13T17:09:37Z

Other sites with related content {{HelpIcon|Help:Databases}}

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	==Other sites with related content {{HelpIcon\|Help:Databases}}==		==Other sites with related content {{HelpIcon\|Help:Databases}}==
	CARD maintains a list of ~~related databases.~~[{{{1\|http://arpcard.mcmaster.ca/?q=node/6947}}} related databases].		CARD maintains a list of [{{{1\|http://arpcard.mcmaster.ca/?q=node/6947}}} antibiotic resistance related databases].

	==Technology==		==Technology==

Agmcarthur: /* Other sites with related content {{HelpIcon|Help:Databases}} */

2011-10-13T17:09:05Z

Other sites with related content {{HelpIcon|Help:Databases}}

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	==Other sites with related content {{HelpIcon\|Help:Databases}}==		==Other sites with related content {{HelpIcon\|Help:Databases}}==
			CARD maintains a list of related databases.[{{{1\|http://arpcard.mcmaster.ca/?q=node/6947}}} related databases].

	==Technology==		==Technology==

Agmcarthur: /* About {{PAGENAME}} */

2011-10-13T17:07:22Z

About {{PAGENAME}}

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	==About {{PAGENAME}}==		==About {{PAGENAME}}==
	[{{{1\|http://arpcard.mcmaster.ca}}} {{PAGENAME}}] is a bioinformatic database of resistance genes, their products and associated phenotypes hosted by the laboratory of Dr. Gerry Wright, Institute of Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.		[{{{1\|http://arpcard.mcmaster.ca}}} {{PAGENAME}}] is a bioinformatic database of resistance genes, their products and associated phenotypes hosted by the laboratory of Dr. Gerry Wright, Institute of Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.

			Addressing the challenge of antibiotic resistance requires the combined efforts of researchers that span inquiry at the molecular, patient, and population levels. Yet, despite the common objective of finding solutions to drug resistance, practitioners of these research areas do not often integrate their research findings. This reality reflects the disparate investigative tools, timelines and specific project aims of these disciplines. Nevertheless, resistance genes and their products are the common elements that bridge antibiotic resistance research from bench to clinic to population. What is lacking in the field is a comprehensive database of resistance genes that includes molecular, clinical, and surveillance data that can serve to unify research. We have established a UK-Canada consortium of antibiotic resistance researchers from all areas of resistance investigation to establish an Antibiotic Resistance Pipeline. Phase 1 of the project is to establish the consortium and begin the construction of a Comprehensive Antibiotic Resistance Database (CARD). This database will form the foundation of phase 2 projects to be funded by other means that will seek to add new information to the database and draw upon it to seek solutions to antibiotic resistance. The Antibiotic Resistance Pipeline provides an opportunity to unify the sub-fields of antibiotic resistance research to the benefit of clinical practice, fundamental research, and drug development.

	==Content==		==Content==

Agmcarthur: /* About {{PAGENAME}} */

2011-10-13T17:06:54Z

About {{PAGENAME}}

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	==About {{PAGENAME}}==		==About {{PAGENAME}}==
	[{{{1\|http://arpcard.mcmaster.ca}}} {{PAGENAME}}] is a bioinformatic database of resistance genes, their products and associated phenotypes.		[{{{1\|http://arpcard.mcmaster.ca}}} {{PAGENAME}}] is a bioinformatic database of resistance genes, their products and associated phenotypes hosted by the laboratory of Dr. Gerry Wright, Institute of Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.

	==Content==		==Content==

Agmcarthur: /* About {{PAGENAME}} */

2011-10-13T17:06:27Z

About {{PAGENAME}}

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	==About {{PAGENAME}}==		==About {{PAGENAME}}==
	~~The~~ [{{{1\|http://arpcard.mcmaster.ca}}} {{PAGENAME}}] is a bioinformatic database of resistance genes, their products and associated phenotypes.		[{{{1\|http://arpcard.mcmaster.ca}}} {{PAGENAME}}] is a bioinformatic database of resistance genes, their products and associated phenotypes.

	==Content==		==Content==

Agmcarthur: /* About {{PAGENAME}} */

2011-10-13T17:06:14Z

About {{PAGENAME}}

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	==About {{PAGENAME}}==		==About {{PAGENAME}}==
	The [{{{1\|http://arpcard.mcmaster.ca}}} {{~~Comprehensive Antibiotic Resistance Database~~}}] is a bioinformatic database of resistance genes, their products and associated phenotypes.		The [{{{1\|http://arpcard.mcmaster.ca}}} {{PAGENAME}}] is a bioinformatic database of resistance genes, their products and associated phenotypes.

	==Content==		==Content==