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References Suggestions


Standard Name


Gene Synonym(s)

ECK2663, b2669, JW2644, hnsB, rsv[1], rsv

Product Desc.

H-NS-like DNA-binding protein with RNA chaperone activity[2][3]

RNA chaperone and DNA-binding protein; suppresses T4 td mutant[4]; modulates micF stability; forms heteromers with, and stabilzed against proteolysis by, the paralogous H-NS protein; transcriptionally repressed by H-NS[5]

Product Synonyms(s)

DNA binding protein, nucleoid-associated[1], B2669[2][1], HnsB[2][1], StpA[2][1] , ECK2663, hnsB, JW2644, rsv, b2669

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s): stpA[2]

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Nucleoid-associated protein.

StpA binds preferably unstructured RNA weakly, with mainly electrostatic interactions that promote RNA folding (Mayer et al. 2007).[5]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. Zhang, A & Belfort, M (1992) Nucleotide sequence of a newly-identified Escherichia coli gene, stpA, encoding an H-NS-like protein. Nucleic Acids Res. 20 6735 PubMed
  5. 5.0 5.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.