EcoliWiki - User contributions [en]

Talk:ada:Gene Product(s)

2024-06-06T19:17:02Z

Siegele: /* updated GO term used for an annotation */ new section

{{Gene_Product(s) talk placeholder}}

== updated GO term used for an annotation ==

Replaced the obsolete term GO:0080111 with GO:0006307 [[User:Siegele|Siegele]] ([[User talk:Siegele|talk]]) 14:17, 6 June 2024 (CDT)

ada:Gene Product(s)

2024-06-06T19:15:27Z

Siegele: Table edited by $2 via TableEdit

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<noinclude>{{TabsTop}}
{{Tab|Quickview|ada}}{{Tab|Gene|ada}}{{Tab On|Gene Product(s)|ada}}{{Tab|Expression|ada}}{{Tab|Evolution|ada}}{{Tab|On One Page|ada}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="W46aa98c9b8d17" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
Ada
|-
!align=left {{table heading style}} |Synonyms
||
''fused DNA-binding transcriptional dual regulator<ref name='LIB:Riley_2006'/>, O6-methylguanine-DNA methyltransferase<ref name='LIB:Riley_2006'/>, B2213<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Ada<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK2205, JW2201, b2213''
|-
!align=left {{table heading style}} |Product description
||
Ada transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

O6-methylguanine-DNA methyltransferase, transcription factor; inducible; DNA repair against methylating and alkylating agents; binds Zn(II)<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.63 2.1.1.63]<ref name='LIB:Riley_2006'/>

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<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Z46aa98cac84ca" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0003677
|
DNA binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004026
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0003677
|
DNA binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0238
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0003700
|
transcription factor activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000005
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0003824
|
catalytic activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR014048
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0003908
|
methylated-DNA-(protein)-cysteine S-methyltransferase activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001497
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0003908
|
methylated-DNA-(protein)-cysteine S-methyltransferase activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR008332
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0003908
|
methylated-DNA-(protein)-cysteine S-methyltransferase activity
|
GOA:spec GO_REF:0000003
|
IEA: Inferred from Electronic Annotation
|
EC:2.1.1.63
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005622
|
intracellular
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000005
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006281
|
DNA repair
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001497
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006281
|
DNA repair
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004026
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006281
|
DNA repair
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR008332
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006281
|
DNA repair
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR014048
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006281
|
DNA repair
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0234
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006350
|
transcription
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0804
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006355
|
regulation of transcription, DNA-dependent
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000005
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006355
|
regulation of transcription, DNA-dependent
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004026
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006974
|
response to DNA damage stimulus
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0227
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008270
|
zinc ion binding
|
PMID:1581309
|
IDA: Inferred from Direct Assay
|

|
F
|
N-terminal domain binds Zn
|
complete
|-
|

|
GO:0008168
|
methyltransferase activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004026
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008168
|
methyltransferase activity
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0489
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008270
|
zinc ion binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004026
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008270
|
zinc ion binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0862
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008270
|
zinc ion binding
|
PMID:1581309
|
IDA: Inferred from Direct Assay
|

|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016740
|
transferase activity
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0808
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0043565
|
sequence-specific DNA binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000005
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0003908
|
methylated-DNA-(protein)-cysteine S-methyltransferase activity
|
PMID:6754717
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0005625
|
soluble fraction
|
PMID:6754717
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete
|-
|

|
GO:0006307
|
DNA dealkylation involved in DNA repair
|
PMID:6754717
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0006307
|
DNA dealkylation involved in DNA repair
|
PMID:
282622
|
IDA: Inferred from Direct Assay
|

|
P
|

|
<div class="mw-parser-output">complete
</div>

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|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="G46aa98ec716d5" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
rplB 
|

|
PMID:16606699
|
Experiment(s):EBI-1142195 
|-
|
Protein
|
rpsC 
|

|
PMID:16606699
|
Experiment(s):EBI-1142195 
|-
|
Protein
|
moeB 
|

|
PMID:16606699
|
Experiment(s):EBI-1142195 
|-
|
Protein
|
fur 
|

|
PMID:16606699
|
Experiment(s):EBI-1142195 
|-
|
Protein
|
rpsG 
|

|
PMID:16606699
|
Experiment(s):EBI-1142195 
|-
|
Protein
|
ybiA 
|

|
PMID:16606699
|
Experiment(s):EBI-1142195 

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</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="U46aa98ed35ea6" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-
|
membrane
|

|

|
From EcoCyc<ref name='LIB:EcoCyc11.1'/>
|

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<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="N46aa98eec4384" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=PD00230 at EcoCyc]
<pre>MKKATCLTDD QRWQSVLARD PNADGEFVFA VRTTGIFCRP SCRARHALRE NVSFYANASE
ALAAGFRPCK RCQPEKANAQ QHRLDKITHA CRLLEQETPV TLEALADQVA MSPFHLHRLF
KATTGMTPKA WQQAWRARRL RESLAKGESV TTSILNAGFP DSSSYYRKAD ETLGMTAKQF
RHGGENLAVR YALADCELGR CLVAESERGI CAILLGDDDA TLISELQQMF PAADNAPADL
MFQQHVREVI ASLNQRDTPL TLPLDIRGTA FQQQVWQALR TIPCGETVSY QQLANAIGKP
KAVRAVASAC AANKLAIIIP CHRVVRGDGT LSGYRWGVSR KAQLLRREAE NEER</pre>
|-
!align=left {{table heading style}} |Length
||
354
|-
!align=left {{table heading style}} |Mol. Wt
||
39.323 kDa
|-
!align=left {{table heading style}} |pI
||
8.8 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
36,440 - 37,940 (calc based on 6 Y, 5 W, and 12 C residues)

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<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Z46aa98ef3d7e3" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
10..75
|
[http://pfam.janelia.org/family/PF02805 PF02805 Metal binding domain of Ada]
|

|
PMID:19920124
|-
|
Domain
|
95..133
|
[http://pfam.janelia.org/family/PF00165 PF00165 Bacterial regulatory helix-turn-helix proteins, AraC family]
|

|
PMID:19920124
|-
|
Domain
|
140..182
|
[http://pfam.janelia.org/family/PF00165 PF00165 Bacterial regulatory helix-turn-helix proteins, AraC family]
|

|
PMID:19920124
|-
|
Domain
|
269..353
|
[http://pfam.janelia.org/family/PF01035 PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain]
|

|
PMID:19920124
|-
|
Domain
|
188..266
|
[http://pfam.janelia.org/family/PF02870 PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain]
|

|
PMID:19920124

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</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="M46a82cf901614" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=ada
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P06134 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P06134 PSI-PRED (P06134)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P06134 Genomes TO Protein (P06134)] (GTOP)

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</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="K46aa98f0046e8" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
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<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="L46aa98f06149e" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16130150 GI:16130150]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_416717.1 GeneID:946710]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0007311
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P06134 UniProtKB/Swiss-Prot:P06134]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG10029
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG10029
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=946710 GeneID:946710]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120000026
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB0028
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

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<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="A46a82cfd89960" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

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<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

ada:Gene Product(s)

2024-06-06T19:12:33Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|ada}}{{Tab|Gene|ada}}{{Tab On|Gene Product(s)|ada}}{{Tab|Expression|ada}}{{Tab|Evolution|ada}}{{Tab|On One Page|ada}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="W46aa98c9b8d17" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
Ada
|-
!align=left {{table heading style}} |Synonyms
||
''fused DNA-binding transcriptional dual regulator<ref name='LIB:Riley_2006'/>, O6-methylguanine-DNA methyltransferase<ref name='LIB:Riley_2006'/>, B2213<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Ada<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK2205, JW2201, b2213''
|-
!align=left {{table heading style}} |Product description
||
Ada transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

O6-methylguanine-DNA methyltransferase, transcription factor; inducible; DNA repair against methylating and alkylating agents; binds Zn(II)<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.63 2.1.1.63]<ref name='LIB:Riley_2006'/>

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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Z46aa98cac84ca" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0003677
|
DNA binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004026
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0003677
|
DNA binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0238
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0003700
|
transcription factor activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000005
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0003824
|
catalytic activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR014048
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0003908
|
methylated-DNA-(protein)-cysteine S-methyltransferase activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001497
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0003908
|
methylated-DNA-(protein)-cysteine S-methyltransferase activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR008332
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0003908
|
methylated-DNA-(protein)-cysteine S-methyltransferase activity
|
GOA:spec GO_REF:0000003
|
IEA: Inferred from Electronic Annotation
|
EC:2.1.1.63
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005622
|
intracellular
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000005
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006281
|
DNA repair
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001497
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006281
|
DNA repair
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004026
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006281
|
DNA repair
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR008332
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006281
|
DNA repair
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR014048
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006281
|
DNA repair
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0234
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006350
|
transcription
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0804
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006355
|
regulation of transcription, DNA-dependent
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000005
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006355
|
regulation of transcription, DNA-dependent
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004026
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006974
|
response to DNA damage stimulus
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0227
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008270
|
zinc ion binding
|
PMID:1581309
|
IDA: Inferred from Direct Assay
|

|
F
|
N-terminal domain binds Zn
|
complete
|-
|

|
GO:0008168
|
methyltransferase activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004026
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008168
|
methyltransferase activity
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0489
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008270
|
zinc ion binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004026
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008270
|
zinc ion binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0862
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008270
|
zinc ion binding
|
PMID:1581309
|
IDA: Inferred from Direct Assay
|

|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016740
|
transferase activity
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0808
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0043565
|
sequence-specific DNA binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000005
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0003908
|
methylated-DNA-(protein)-cysteine S-methyltransferase activity
|
PMID:6754717
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0005625
|
soluble fraction
|
PMID:6754717
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete
|-
|

|
GO:0006307
|
DNA demethylation
|
PMID:6754717
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0006307
|
DNA dealkylation involved in DNA repair
|
PMID:
282622
|
IDA: Inferred from Direct Assay
|

|
P
|

|
<div class="mw-parser-output">complete
</div>

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|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="G46aa98ec716d5" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
rplB 
|

|
PMID:16606699
|
Experiment(s):EBI-1142195 
|-
|
Protein
|
rpsC 
|

|
PMID:16606699
|
Experiment(s):EBI-1142195 
|-
|
Protein
|
moeB 
|

|
PMID:16606699
|
Experiment(s):EBI-1142195 
|-
|
Protein
|
fur 
|

|
PMID:16606699
|
Experiment(s):EBI-1142195 
|-
|
Protein
|
rpsG 
|

|
PMID:16606699
|
Experiment(s):EBI-1142195 
|-
|
Protein
|
ybiA 
|

|
PMID:16606699
|
Experiment(s):EBI-1142195 

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</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="U46aa98ed35ea6" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-
|
membrane
|

|

|
From EcoCyc<ref name='LIB:EcoCyc11.1'/>
|

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<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="N46aa98eec4384" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=PD00230 at EcoCyc]
<pre>MKKATCLTDD QRWQSVLARD PNADGEFVFA VRTTGIFCRP SCRARHALRE NVSFYANASE
ALAAGFRPCK RCQPEKANAQ QHRLDKITHA CRLLEQETPV TLEALADQVA MSPFHLHRLF
KATTGMTPKA WQQAWRARRL RESLAKGESV TTSILNAGFP DSSSYYRKAD ETLGMTAKQF
RHGGENLAVR YALADCELGR CLVAESERGI CAILLGDDDA TLISELQQMF PAADNAPADL
MFQQHVREVI ASLNQRDTPL TLPLDIRGTA FQQQVWQALR TIPCGETVSY QQLANAIGKP
KAVRAVASAC AANKLAIIIP CHRVVRGDGT LSGYRWGVSR KAQLLRREAE NEER</pre>
|-
!align=left {{table heading style}} |Length
||
354
|-
!align=left {{table heading style}} |Mol. Wt
||
39.323 kDa
|-
!align=left {{table heading style}} |pI
||
8.8 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
36,440 - 37,940 (calc based on 6 Y, 5 W, and 12 C residues)

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<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
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|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
10..75
|
[http://pfam.janelia.org/family/PF02805 PF02805 Metal binding domain of Ada]
|

|
PMID:19920124
|-
|
Domain
|
95..133
|
[http://pfam.janelia.org/family/PF00165 PF00165 Bacterial regulatory helix-turn-helix proteins, AraC family]
|

|
PMID:19920124
|-
|
Domain
|
140..182
|
[http://pfam.janelia.org/family/PF00165 PF00165 Bacterial regulatory helix-turn-helix proteins, AraC family]
|

|
PMID:19920124
|-
|
Domain
|
269..353
|
[http://pfam.janelia.org/family/PF01035 PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain]
|

|
PMID:19920124
|-
|
Domain
|
188..266
|
[http://pfam.janelia.org/family/PF02870 PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain]
|

|
PMID:19920124

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|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="M46a82cf901614" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=ada
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P06134 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P06134 PSI-PRED (P06134)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P06134 Genomes TO Protein (P06134)] (GTOP)

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</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="K46aa98f0046e8" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
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<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="L46aa98f06149e" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16130150 GI:16130150]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_416717.1 GeneID:946710]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0007311
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P06134 UniProtKB/Swiss-Prot:P06134]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG10029
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG10029
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=946710 GeneID:946710]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120000026
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB0028
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

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<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="A46a82cfd89960" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

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|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

Talk:mltD:Gene Product(s)

2023-03-21T16:09:35Z

Siegele: /* delete annotation due to obsoletion of GO:0051353 positive regulation of oxidoreductase activity */ new section

{{Gene_Product(s) talk placeholder}}

== delete annotation due to obsoletion of GO:0051353 positive regulation of oxidoreductase activity ==

GO:0051353
positive regulation of oxidoreductase activity
PMID:1663890[5]
IMP: Inferred from Mutant Phenotype
P
complete

ygeR:Gene Product(s)

2023-02-11T19:08:27Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|ygeR}}{{Tab|Gene|ygeR}}{{Tab On|Gene Product(s)|ygeR}}{{Tab|Expression|ygeR}}{{Tab|Evolution|ygeR}}{{Tab|On One Page|ygeR}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="Z46aac36fb7bea" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
YgeR
|-
!align=left {{table heading style}} |Synonyms
||
''Tetratricopeptide repeat transcriptional regulator<ref name='LIB:Riley_2006'/>, B2865<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YgeR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK2861, JW2833, b2865''
|-
!align=left {{table heading style}} |Product description
||
putative lipoprotein<ref name='LIB:EcoCyc10.6'/>; putative lipoprotein; predicted DNA-binding transcriptional regulator<ref name='LIB:EcoCyc11.1'/>

Novel lipoprotein, function unknown, metalloprotease homolog; M23 family<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="U46aac370c4f5a" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0000920
|
septum digestion after cytokinesis
|
PMID:19525345
|
IGI: Inferred from Genetic Interaction
|
UniProtKB:P0ADA3
UniProtKB:P37690
UniProtKB:P0AFS9

|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0004222
|
metalloendopeptidase activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR002886
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-1003
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006508
|
proteolysis
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR002886
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0000920
|
cytokinetic cell separation
|
PMID:19525345
|
IGI: Inferred from Genetic Interaction
|
UniProtKB:P37690

|
P
|

|
complete
|-
|

|
GO:0016020
|
membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0472
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016998
|
cell wall macromolecule catabolic process
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR002482
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0000920
|
cytokinetic cell separation
|
PMID:19525345
|
IGI: Inferred from Genetic Interaction
|
UniProtKB:P0ADA3
UniProtKB:P37690
UniProtKB:Q46798

|
P
|

|
complete
|-
|

|
GO:0016998
|
cell wall macromolecule catabolic process
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR018392
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0031225
|
anchored to membrane
|
GO_REF:0000023
|
IEA: Inferred from Electronic Annotation
|
SP_SL:SL-9901
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26088.U46aac370c4f5a&page=26088&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="O46aac3755a909" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
rplL
|

|
PMID:19402753
|
LCMS(ID Probability):99.6

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26088.O46aac3755a909&page=26088&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="X46a8596e392e7" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-
|
Outer membrane
|
|PMID:15174130
|
[http://www.york.ac.uk/res/thomas/Echolocation.cfm?EB_SubLocID=EB2860 EchoLocation:ygeR]
|

|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26088.X46a8596e392e7&page=26088&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="Q46aac37746258" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=G7484-MONOMER at EcoCyc]
<pre>MFFKRGKILS AGRLNKKSLG IVMLLSVGLL LAGCSGSKSS DTGTYSGSVY TVKRGDTLYR
ISRTTGTSVK ELARLNGISP PYTIEVGQKL KLGGAKSSSI TRKSTAKSTT KTASVTPSSA
VPKSSWPPVG QRCWLWPTTG KVIMPYSTAD GGNKGIDISA PRGTPIYAAG AGKVVYVGNQ
LRGYGNLIMI KHSEDYITAY AHNDTMLVNN GQSVKAGQKI ATMGSTDAAS VRLHFQIRYR
ATAIDPLRYL PPQGSKPKC</pre>
|-
!align=left {{table heading style}} |Length
||
259
|-
!align=left {{table heading style}} |Mol. Wt
||
27.555 kDa
|-
!align=left {{table heading style}} |pI
||
10.6 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
34,380 - 34,755 (calc based on 12 Y, 3 W, and 3 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26088.Q46aac37746258&page=26088&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="G46aac377b6336" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
motif
|
1-25
|
[[uniprotmanual:signal|UniProt Manual:Signal Peptides]]
|
[http://www.uniprot.org/uniprot/Q46798#section_features UniProt:Q46798]
|

|-
|
Domain
|
42..85
|
[http://pfam.janelia.org/family/PF01476 PF01476 LysM domain]
|

|
PMID:19920124
|-
|
Domain
|
143..238
|
[http://pfam.janelia.org/family/PF01551 PF01551 Peptidase family M23]
|

|
PMID:19920124

|- class="tableEdit_footer"
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|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="B46a8596fcc1fe" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=ygeR
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/Q46798 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=Q46798 PSI-PRED (Q46798)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=Q46798 Genomes TO Protein (Q46798)] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26088.B46a8596fcc1fe&page=26088&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="F46aac37880d79" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26088.F46aac37880d79&page=26088&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="W46aac378dfd8f" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/90111503 GI:90111503]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_417341.4 GeneID:947352]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0009407
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/Q46798 UniProtKB/Swiss-Prot:Q46798]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:G7484
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG13048
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=947352 GeneID:947352]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120004047
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB2860
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="X46a859735179b" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26088.X46a859735179b&page=26088&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

Category:Genes with homologs in Xenopus tropicalis

2022-09-28T15:06:08Z

Siegele:

This category lists ''E. coli'' K-12 genes that have homologs in the genome of the [https://en.wikipedia.org/wiki/Western_clawed_frog Western clawed frog], ''Xenopus tropicalis''.

coaE:Gene Product(s)

2022-03-15T17:55:10Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|coaE}}{{Tab|Gene|coaE}}{{Tab On|Gene Product(s)|coaE}}{{Tab|Expression|coaE}}{{Tab|Evolution|coaE}}{{Tab|On One Page|coaE}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="L46aa1be03ae3b" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
CoaE
|-
!align=left {{table heading style}} |Synonyms
||
''dephospho-CoA kinase<ref name='LIB:Riley_2006'/>, B0103<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YacE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CoaE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0103, JW0100, yacE, b0103''
|-
!align=left {{table heading style}} |Product description
||
EG12312<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

Dephospho-CoA kinase; final step in CoA synthesis<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.24 2.7.1.24]<ref name='LIB:Riley_2006'/>

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19696.L46aa1be03ae3b&page=19696&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|}


<protect></protect>
===Notes===
''yacE'' is reported to encode dephospho-CoA kinase, which catalyzes the final step of [[wikipedia:Coenzyme A|Coenzyme A]] anabolism.<ref name='PMID:11292795 '/>

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="W46aa1be1330c3" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0030288
|
outer membrane-bounded periplasmic space
|

|

|

|
C
|
Seeded from Riley et al 2006 <ref name='LIB:Riley_2006'/>.
|
Missing: evidence, reference
|-
|

|
GO:0000166
|
nucleotide binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0547
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GOA:hamap GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_00376
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001977
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0067
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0015937
|
coenzyme A biosynthetic process
|
GOA:hamap GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_00376
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0015937
|
coenzyme A biosynthetic process
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001977
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0015937
|
coenzyme A biosynthetic process
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0173
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0004140
|
dephospho-CoA kinase activity
|
PMID:12538896
|
ISS: Inferred from Sequence or Structural Similarity
|
UniProtKB:P44920

|
F
|

|
complete
|-
|

|
GO:0004140
|
dephospho-CoA kinase activity
|
PMID:11292795
|
IDA: Inferred from Direct Assay
|

|
F
|
assay of purified recombinant CoaE protein (Table 2 and accompanying text).
|
complete
|-
|

|
GO:0005829
|
cytosol
|
PMID:26602691
|
IEA: Inferred from Electronic Annotation
|

|
C
|
From EcoCyc_25.5
|
complete

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19696.W46aa1be1330c3&page=19696&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="M46aa1be526ab7" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
dps
|

|
PMID:19402753
|
LCMS(ID Probability):99.6
|-
|
Protein
|
speD
|

|
PMID:19402753
|
LCMS(ID Probability):99.6

|- class="tableEdit_footer"
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|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Y46a7317d20575" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19696.Y46a7317d20575&page=19696&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="B46aa1be6d6b97" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=EG12312-MONOMER at EcoCyc]
<pre>MRYIVALTGG IGSGKSTVAN AFADLGINVI DADIIARQVV EPGAPALHAI ADHFGANMIA
ADGTLQRRAL RERIFANPEE KNWLNALLHP LIQQETQHQI QQATSPYVLW VVPLLVENSL
YKKANRVLVV DVSPETQLKR TMQRDDVTRE HVEQILAAQA TREARLAVAD DVIDNNGAPD
AIASDVARLH AHYLQLASQF VSQEKP</pre>
|-
!align=left {{table heading style}} |Length
||
206
|-
!align=left {{table heading style}} |Mol. Wt
||
22.621 kDa
|-
!align=left {{table heading style}} |pI
||
6.2 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
16,960 (calc based on 4 Y, 2 W, and 0 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19696.B46aa1be6d6b97&page=19696&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="R46aa1be73aa2b" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
3..181
|
[http://pfam.janelia.org/family/PF01121 PF01121 Dephospho-CoA kinase]
|

|
PMID:19920124

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19696.R46aa1be73aa2b&page=19696&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="J46aa1be783325" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=coaE
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P0A6I9 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P0A6I9 PSI-PRED (P0A6I9)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P0A6I9 Genomes TO Protein (P0A6I9)] (GTOP)

|- class="tableEdit_footer"
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|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="V46aa1bea7d7ee" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19696.V46aa1bea7d7ee&page=19696&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="T46aa1beac6d55" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16128096 GI:16128096]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_414645.1 GeneID:949060]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0000357
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P0A6I9 UniProtKB/Swiss-Prot:P0A6I9]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG12312
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG12312
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=949060 GeneID:949060]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120002189
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB2218
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="B46a73184e8af1" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
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|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

Talk:rfe:Gene Product(s)

2021-07-06T20:56:27Z

Siegele: /* delete annotation to GO:0008144 drug binding */

{{Gene_Product(s) talk placeholder}}

== deleted annotation to GO:0008144 drug binding ==

This annotation was deleted because GO:0008144 was made obsolete. See explanation at [https://github.com/geneontology/go-annotation/issues/3166 #3166] [[User:Siegele|Siegele]] ([[User talk:Siegele|talk]]) 15:56, 6 July 2021 (CDT)

Talk:msbA:Gene Product(s)

2021-07-06T20:55:44Z

Siegele: /* delete annotation to GO:0008144 drug binding */ new section

{{Gene_Product(s) talk placeholder}}

== delete annotation to GO:0008144 drug binding ==

The annotation of msbA to GO:0008144 drug binding was deleted because the term has been made obsolete. See explanation at [https://github.com/geneontology/go-annotation/issues/3166 3166] [[User:Siegele|Siegele]] ([[User talk:Siegele|talk]]) 15:55, 6 July 2021 (CDT)

msbA:Gene Product(s)

2021-07-06T20:54:07Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|msbA}}{{Tab|Gene|msbA}}{{Tab On|Gene Product(s)|msbA}}{{Tab|Expression|msbA}}{{Tab|Evolution|msbA}}{{Tab|On One Page|msbA}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="S46aa4b46a0d97" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
MsbA
|-
!align=left {{table heading style}} |Synonyms
||
''fused lipid transporter subunits of ABC superfamily: membrane component<ref name='LIB:Riley_2006'/>, ATP-binding component<ref name='LIB:Riley_2006'/>, B0914<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsbA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ECK0905, JW0897, b0914''
|-
!align=left {{table heading style}} |Product description
||
ATP-binding transport protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

Lipid exporter to the outer membrane; exports LPS, phospholipids, and lipid A; drug export and resistance; ABC transporter flippase; biogenesis of outer membrane; lipid-activated ATPase<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="B46aa4b479d593" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0005515
|
protein binding
|
PMID:18344567
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0034040
|
lipid-transporting ATPase activity
|
PMID:18344567
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0067
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0997
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-1003
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006869
|
lipid transport
|
GOA:hamap GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_01703
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006869
|
lipid transport
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011917
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006869
|
lipid transport
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0445
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016020
|
membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0472
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016020
|
membrane
|
PMID:16858726
|
IDA: Inferred from Direct Assay
|

|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001140
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0812
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008289
|
lipid binding
|
PMID:18344567
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011917
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0812
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GO_REF:0000023
|
IEA: Inferred from Electronic Annotation
|
SP_SL:SL-9909
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0055085
|
transmembrane transport
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001140
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0055085
|
transmembrane transport
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011527
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005319
|
lipid transporter activity
|
GOA:hamap GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_01703
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001140
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR003439
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011527
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011917
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR017871
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.B46aa4b479d593&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="S46aa4b481bdb2" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.S46aa4b481bdb2&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="G46a7dd1c2b935" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-
|
plasma membrane
|
C-terminus localized in the cytoplasm with 6 predicted transmembrane domains
|
Daley et al. (2005) <ref name=PMID:15919996/>
|

|

|- class="tableEdit_footer"
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|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="W46aa4b49d4e91" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=EG10613-MONOMER at EcoCyc]
<pre>MHNDKDLSTW QTFRRLWPTI APFKAGLIVA GVALILNAAS DTFMLSLLKP LLDDGFGKTD
RSVLVWMPLV VIGLMILRGI TSYVSSYCIS WVSGKVVMTM RRRLFGHMMG MPVSFFDKQS
TGTLLSRITY DSEQVASSSS GALITVVREG ASIIGLFIMM FYYSWQLSII LIVLAPIVSI
AIRVVSKRFR NISKNMQNTM GQVTTSAEQM LKGHKEVLIF GGQEVETKRF DKVSNRMRLQ
GMKMVSASSI SDPIIQLIAS LALAFVLYAA SFPSVMDSLT AGTITVVFSS MIALMRPLKS
LTNVNAQFQR GMAACQTLFT ILDSEQEKDE GKRVIERATG DVEFRNVTFT YPGRDVPALR
NINLKIPAGK TVALVGRSGS GKSTIASLIT RFYDIDEGEI LMDGHDLREY TLASLRNQVA
LVSQNVHLFN DTVANNIAYA RTEQYSREQI EEAARMAYAM DFINKMDNGL DTVIGENGVL
LSGGQRQRIA IARALLRDSP ILILDEATSA LDTESERAIQ AALDELQKNR TSLVIAHRLS
TIEKADEIVV VEDGVIVERG THNDLLEHRG VYAQLHKMQF GQ</pre>
|-
!align=left {{table heading style}} |Length
||
582
|-
!align=left {{table heading style}} |Mol. Wt
||
64.462 kDa
|-
!align=left {{table heading style}} |pI
||
8.8 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
46,870 - 47,120 (calc based on 13 Y, 5 W, and 2 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.W46aa4b49d4e91&page=21674&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big>
<table>
<tr align="left" valign="top">
<td>


{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="M46aa4b4a3c914" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
24..298
|
[http://pfam.janelia.org/family/PF00664 PF00664 ABC transporter transmembrane region]
|

|
PMID:19920124
|-
|
Domain
|
383..509
|
[http://pfam.janelia.org/family/PF00005 PF00005 ABC transporter]
|

|
PMID:19920124

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.M46aa4b4a3c914&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}


</td>
<td>


<motif_map/>
{{TMHMM Picture|msbA}}
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="A46a7dd1dc9beb" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=msbA
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P60752 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P60752 PSI-PRED (P60752)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P60752 Genomes TO Protein (P60752)] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.A46a7dd1dc9beb&page=21674&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Q46aa4b4ad5f6c" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.Q46aa4b4ad5f6c&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="C46aa4b4b2e146" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16128881 GI:16128881]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_415434.1 GeneID:945530]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0003113
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P60752 UniProtKB/Swiss-Prot:P60752]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG10613
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG10613
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=945530 GeneID:945530]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120000606
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB0608
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

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<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="I46a7dd2144523" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

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|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:RefGenome_Annotated_Gene]]
[[Category:Pfam:PF00664_!_ABC transporter transmembrane region]]
[[Category:Pfam:PF00005_!_ABC transporter]]
[[Category:RefGenome_Annotated_Gene]]

Talk:rfe:Gene Product(s)

2021-07-06T20:52:54Z

Siegele: /* delete annotation to GO:0008144 drug binding */ new section

{{Gene_Product(s) talk placeholder}}

== delete annotation to GO:0008144 drug binding ==

This annotation was deleted because GO:0008144 was made obsolete. See explanation at [https://github.com/geneontology/go-annotation/issues/3166 #3166]

rfe:Gene Product(s)

2021-07-06T20:50:53Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|rfe}}{{Tab|Gene|rfe}}{{Tab On|Gene Product(s)|rfe}}{{Tab|Expression|rfe}}{{Tab|Evolution|rfe}}{{Tab|On One Page|rfe}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="Q46ab0374c5ac2" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
Rfe
|-
!align=left {{table heading style}} |Synonyms
||
''UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase<ref name='LIB:Riley_2006'/>, B3784<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, WecA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Rfe<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3776, JW3758, wecA, b3784''
|-
!align=left {{table heading style}} |Product description
||

UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-P transferase; ECA and O-antigen synthesis, tunicamycin sensitivity<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.- 2.4.1.-]<ref name='LIB:Riley_2006'/>

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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="D46ab0375e2b34" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0000287
|
magnesium ion binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR012750
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0000287
|
magnesium ion binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0460
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0997
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-1003
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008963
|
phospho-N-acetylmuramoyl-pentapeptide-transferase activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000715
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0009103
|
lipopolysaccharide biosynthetic process
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR012750
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0009103
|
lipopolysaccharide biosynthetic process
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0448
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0009276
|
Gram-negative-bacterium-type cell wall
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR012750
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016020
|
membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0472
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
PMID:18723618
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000715
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008963
|
phospho-N-acetylmuramoyl-pentapeptide-transferase activity
|
PMID:18723618
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR012750
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0000287
|
magnesium ion binding
|
PMID:18723618
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0812
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GO_REF:0000023
|
IEA: Inferred from Electronic Annotation
|
SP_SL:SL-9909
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016740
|
transferase activity
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0808
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016757
|
transferase activity, transferring glycosyl groups
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0328
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016780
|
phosphotransferase activity, for other substituted phosphate groups
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR012750
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0030145
|
manganese ion binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR012750
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0030145
|
manganese ion binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0464
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete

|- class="tableEdit_footer"
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<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="R46ab0380dc1e7" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence

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|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Z46ab0381ada75" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-
|
plasma membrane
|
C-terminus localized in the cytoplasm with 11 predicted transmembrane domains
|
Daley et al. (2005) <ref name=PMID:15919996/>
|

|

|-
|
membrane
|

|

|
From EcoCyc<ref name='LIB:EcoCyc11.1'/>
|

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<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="D46ab038371e48" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=GLCNACPTRANS-MONOMER at EcoCyc]
<pre>MNLLTVSTDL ISIFLFTTLF LFFARKVAKK VGLVDKPNFR KRHQGLIPLV GGISVYAGIC
FTFGIVDYYI PHASLYLACA GVLVFIGALD DRFDISVKIR ATIQAAVGIV MMVFGKLYLS
SLGYIFGSWE MVLGPFGYFL TLFAVWAAIN AFNMVDGIDG LLGGLSCVSF AAIGMILWFD
GQTSLAIWCF AMIAAILPYI MLNLGILGRR YKVFMGDAGS TLIGFTVIWI LLETTQGKTH
PISPVTALWI IAIPLMDMVA IMYRRLRKGM SPFSPDRQHI HHLIMRAGFT SRQAFVLITL
AAALLASIGV LAEYSHFVPE WVMLVLFLLA FFLYGYCIKR AWKVARFIKR VKRRLRRNRG
GSPNLTK</pre>
|-
!align=left {{table heading style}} |Length
||
367
|-
!align=left {{table heading style}} |Mol. Wt
||
40.959 kDa
|-
!align=left {{table heading style}} |pI
||
10.4 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
63,370 - 63,995 (calc based on 13 Y, 8 W, and 5 C residues)

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|}


<big>'''Domains/Motifs/Modification Sites'''</big>
<table>
<tr align="left" valign="top">
<td>


{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="E46ab0383e9319" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
73..235
|
[http://pfam.janelia.org/family/PF00953 PF00953 Glycosyl transferase family 4]
|

|
PMID:19920124

|- class="tableEdit_footer"
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|}


</td>
<td>


<motif_map/>
{{TMHMM Picture|rfe}}
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="S46a88e00efe00" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=rfe
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P0AC78 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P0AC78 PSI-PRED (P0AC78)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P0AC78 Genomes TO Protein (P0AC78)] (GTOP)

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</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="D46ab0384c12dd" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="R46ab038535a85" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16131640 GI:16131640]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_418231.1 GeneID:948789]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0012366
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P0AC78 UniProtKB/Swiss-Prot:P0AC78]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG10840
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG10840
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=948789 GeneID:948789]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120000831
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB0833
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

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<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="L46a88e03af876" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.28170.L46a88e03af876&page=28170&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

Category:Strain:MMT

2021-03-30T17:04:08Z

Siegele: Table edited by $2 via TableEdit

{{See|Help:Strains|strains}}
<protect>

{| id="E4e551ec194c31" class=" tableEdit Strain_Geneology_Table dataTable"

|-
!align=left {{table_heading_style}} |Name
||
MMT
|-
!align=left {{table_heading_style}} |Synonyms
||

|-
!align=left {{table_heading_style}} |Genotype
||
''supE44(=glnX44(AS)) rfbC1 thyA753 endA1 spoT1? thi-1 hsdR17 creC510''

Note: creC510 is listed in genotype of parent strain MM294 reported at CGSC
|-
!align=left {{table_heading_style}} |Phenotype
||

|-
!align=left {{table_heading_style}} |Plasmids
||
F-
|-
!align=left {{table_heading_style}} |Phage
||
λ-
|-
!align=left {{table_heading_style}} |Sources
||

|-
!align=left {{table_heading_style}} |Construction
||
thyA was introduced into MM294 by selection with 50 ug trimethoprim/ml
|-
!align=left {{table_heading_style}} |References
||
PMID:6345791

|- class="tableEdit_footer"
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|}
</protect>

== Notes ==

==References==
{{RefHelp}}
<references/>

__NOTOC__
[[Category:Strain:MM294]]

Category:Strain:MMT

2021-03-30T16:59:12Z

Siegele: Table edited by $2 via TableEdit

{{See|Help:Strains|strains}}
<protect>

{| id="E4e551ec194c31" class=" tableEdit Strain_Geneology_Table dataTable"

|-
!align=left {{table_heading_style}} |Name
||
MMT
|-
!align=left {{table_heading_style}} |Synonyms
||

|-
!align=left {{table_heading_style}} |Genotype
||
''supE44 rfbD1? thyA753 endA1 spoT1 thiE1 hsdR17''
|-
!align=left {{table_heading_style}} |Phenotype
||

|-
!align=left {{table_heading_style}} |Plasmids
||
F-
|-
!align=left {{table_heading_style}} |Phage
||
λ-
|-
!align=left {{table_heading_style}} |Sources
||

|-
!align=left {{table_heading_style}} |Construction
||
thyA was introduced into MM294 by selection with 50 ug trimethoprim/ml
|-
!align=left {{table_heading_style}} |References
||
PMID:6345791

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=63ce1649aab8b3180235b0af7618f667.179947.E4e551ec194c31&page=179947&pagename={{FULLPAGENAMEE}}&type=1&template=Strain_Geneology_Table edit table]</div> ||
|}
</protect>

== Notes ==

==References==
{{RefHelp}}
<references/>

__NOTOC__
[[Category:Strain:MM294]]

Category:Strain:MM294A

2021-03-30T16:50:14Z

Siegele: Table edited by $2 via TableEdit

{{See|Help:Strains|strains}}
<protect>

{| id="M4e551fb5eb438" class=" tableEdit Strain_Geneology_Table dataTable"

|-
!align=left {{table_heading_style}} |Name
||
MM294A
|-
!align=left {{table_heading_style}} |Synonyms
||

|-
!align=left {{table_heading_style}} |Genotype
||
''pro-82 glnV44(AS) rfbC1 endA1 spoT1 thi-1 hsdR17 crec510''
|-
!align=left {{table_heading_style}} |Phenotype
||

|-
!align=left {{table_heading_style}} |Plasmids
||
F-
|-
!align=left {{table_heading_style}} |Phage
||
λ-
|-
!align=left {{table_heading_style}} |Sources
||
[http://cgsc.biology.yale.edu/Strain.php?ID=6793 CGSC:6051]
|-
!align=left {{table_heading_style}} |Construction
||
Strain MM294A is a spontaneous pro- derivative of M.Meselson's MM294
|-
!align=left {{table_heading_style}} |References
||
PMID:6323260
PMID:4568763

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=63ce1649aab8b3180235b0af7618f667.179949.M4e551fb5eb438&page=179949&pagename={{FULLPAGENAMEE}}&type=1&template=Strain_Geneology_Table edit table]</div> ||
|}
</protect>

== Notes ==

==References==
{{RefHelp}}
<references/>

__NOTOC__
[[Category:Strain:MM294]]

Category:Strain:MM294

2021-03-30T16:47:37Z

Siegele: Table edited by $2 via TableEdit

{{See|Help:Strains|strains}}
<protect>

{| id="B4e551dec7e488" class=" tableEdit Strain_Geneology_Table dataTable"

|-
!align=left {{table_heading_style}} |Name
||
MM294
|-
!align=left {{table_heading_style}} |Synonyms
||

|-
!align=left {{table_heading_style}} |Genotype
||
''glnX44(AS) rfbC1 endA1 spoT1 thiE1 hsdR17 creC510''
|-
!align=left {{table_heading_style}} |Phenotype
||

|-
!align=left {{table_heading_style}} |Plasmids
||
F-
|-
!align=left {{table_heading_style}} |Phage
||
λ-
|-
!align=left {{table_heading_style}} |Sources
||
[http://cgsc.biology.yale.edu/Strain.php?ID=5439 CGSC:6315]
|-
!align=left {{table_heading_style}} |Construction
||
Strain MM294 is a N-methyl-N'-nitrosoguanidine treated isolate of strain 1100
|-
!align=left {{table_heading_style}} |References
||
PMID:4868368
PMID:4568763

|- class="tableEdit_footer"
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|}
</protect>

== Notes ==

==References==
{{RefHelp}}
<references/>

__NOTOC__
[[Category:Strain:1100]]

ATCC 8739

2020-07-28T18:46:28Z

Siegele:

Although some confusion existed when this strain was originally sequenced, ATCC 8739 is an ''E. coli'' Crooks (or Crookes or Crook's) strain (see discussion page).

gntT:Gene Product(s)

2020-07-25T21:08:02Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|gntT}}{{Tab|Gene|gntT}}{{Tab On|Gene Product(s)|gntT}}{{Tab|Expression|gntT}}{{Tab|Evolution|gntT}}{{Tab|On One Page|gntT}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="I46aae7db50d8f" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
GntT
|-
!align=left {{table heading style}} |Synonyms
||
''gluconate transporter, high-affinity GNT I system<ref name='LIB:Riley_2006'/>, B3415<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YhgC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, UsgA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GntS<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GntM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GntT<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3402, gntM, gntTalpha, JW5690, usgA, yhgC, b3415''
|-
!align=left {{table heading style}} |Product description
||
GntT Gluconate Gnt transporter<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

High-affinity gluconate transport<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27322.I46aae7db50d8f&page=27322&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="T46aae7dc748ef" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0997
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-1003
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006810
|
transport
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0813
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008643
|
carbohydrate transport
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0762
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0015128
|
gluconate transmembrane transporter activity
|
PMID:9358057
|
IMP: Inferred from Mutant Phenotype
|

|
F
|
Assayed gluconate transport in a mutant strain transformed with either pGNTT20, which carries the ''gntT'' gene, or pBR322 (Fig. 2).
|
complete
|-
|

|
GO:0035429
|
gluconate transmembrane transport
|
PMID:9358057
|
IMP: Inferred from Mutant Phenotype
|

|
P
|
Fig. 2
|
complete
|-
|

|
GO:0016020
|
membrane
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR003474
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016020
|
membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0472
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0812
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GO_REF:0000023
|
IEA: Inferred from Electronic Annotation
|
SP_SL:SL-9909
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0019521
|
D-gluconate metabolic process
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0311
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005887
|
integral to plasma membrane
|
PMID:9045817
|
ISM: Inferred from Sequence Model
|

|
C
|
TOPPRED<ref name='PMID:1593632'/>
|
Missing: with/from

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27322.T46aae7dc748ef&page=27322&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="P46aae7dfb13b8" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27322.P46aae7dfb13b8&page=27322&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="L46aae7e07f560" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-
|
plasma membrane
|
C-terminus localized to the periplasm with 10 predicted transmembrane domains
|
Daley et al. (2005) <ref name=PMID:15919996/>
|

|

|-
|
plasma membrane
|

|

|
From EcoCyc<ref name='LIB:EcoCyc11.1'/>
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27322.L46aae7e07f560&page=27322&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="U46aae7e234b8f" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=GNTT-MONOMER at EcoCyc]
<pre>MPLVIVAIGV ILLLLLMIRF KMNGFIALVL VALAVGLMQG MPLDKVIGSI KAGVGGTLGS
LALIMGFGAM LGKMLADCGG AQRIATTLIA KFGKKHIQWA VVLTGFTVGF ALFYEVGFVL
MLPLVFTIAA SANIPLLYVG VPMAAALSVT HGFLPPHPGP TAIATIFNAD MGKTLLYGTI
LAIPTVILAG PVYARVLKGI DKPIPEGLYS AKTFSEEEMP SFGVSVWTSL VPVVLMAMRA
IAEMILPKGH AFLPVAEFLG DPVMATLIAV LIAMFTFGLN RGRSMDQIND TLVSSIKIIA
MMLLIIGGGG AFKQVLVDSG VDKYIASMMH ETNISPLLMA WSIAAVLRIA LGSATVAAIT
AGGIAAPLIA TTGVSPELMV IAVGSGSVIF SHVNDPGFWL FKEYFNLTIG ETIKSWSMLE
TIISVCGLVG CLLLNMVI</pre>
|-
!align=left {{table heading style}} |Length
||
438
|-
!align=left {{table heading style}} |Mol. Wt
||
45.968 kDa
|-
!align=left {{table heading style}} |pI
||
8.4 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
37,930 - 38,305 (calc based on 7 Y, 5 W, and 3 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27322.U46aae7e234b8f&page=27322&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big>
<table>
<tr align="left" valign="top">
<td>


{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="K46aae7e2ac824" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
1..437
|
[http://pfam.janelia.org/family/PF02447 PF02447 GntP family permease]
|

|
PMID:19920124

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27322.K46aae7e2ac824&page=27322&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}


</td>
<td>


<motif_map/>
{{TMHMM Picture|gntT}}
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="Z46a877e3a8c15" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=gntT
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P39835 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P39835 PSI-PRED (P39835)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P39835 Genomes TO Protein (P39835)] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27322.Z46a877e3a8c15&page=27322&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="W46aae7e37ed92" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27322.W46aae7e37ed92&page=27322&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="J46aae7e3e17f3" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/49176350 GI:49176350]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/YP_026217.1 GeneID:947924]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0011148
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P39835 UniProtKB/Swiss-Prot:P39835]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG12380
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG12380
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=947924 GeneID:947924]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120002247
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB2282
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27322.J46aae7e3e17f3&page=27322&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="C46a877e667e97" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27322.C46a877e667e97&page=27322&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

ttdR:Gene Product(s)

2020-07-25T21:00:35Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|ttdR}}{{Tab|Gene|ttdR}}{{Tab On|Gene Product(s)|ttdR}}{{Tab|Expression|ttdR}}{{Tab|Evolution|ttdR}}{{Tab|On One Page|ttdR}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="J46aacf3a5d570" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
TtdR
|-
!align=left {{table heading style}} |Synonyms
||
''predicted DNA-binding transcriptional regulator<ref name='LIB:Riley_2006'/>, TtdR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B3060<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YgiP<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , dan, ECK3050, JW3032, ygiP, b3060''
|-
!align=left {{table heading style}} |Product description
||
predicted DNA-binding transcriptional regulator LYSR-type<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

Transcriptional activator of ttdAB-ygjE, tartrate-inducible; required for tartrate utilization <ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.J46aacf3a5d570&page=26540&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="O46aacf3b6f8a9" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0003700
|
transcription factor activity
|
PMID:15556475
|
ISS: Inferred from Sequence or Structural Similarity
|
Swiss-Prot:P03030
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0003700
|
sequence-specific DNA binding transcription factor activity
|
PMID:16804186
|
IMP: Inferred from Mutant Phenotype
|

|
F
|

|
complete
|-
|

|
GO:0003700
|
transcription factor activity
|
PMID:19661178
|
IDA: Inferred from Direct Assay
|

|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0001216
|
DNA-binding transcription activator activity
|
PMID:16804186
|
IMP: Inferred from Mutant Phenotype
|

|
F
|

|
complete
|-
|

|
GO:0001216
|
DNA-binding transcription activator activity
|
PMID:19661178
|
IDA: Inferred from Direct Assay
|

|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0045893
|
positive regulation of transcription, DNA-templated
|
PMID:15556475
|
ISS: Inferred from Sequence or Structural Similarity
|
Swiss-Prot:P03030

|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0045893
|
positive regulation of transcription, DNA-templated
|
PMID:16804186
|
IMP: Inferred from Mutant Phenotype
|

|
P
|

|
complete
|-
|

|
GO:0045893
|
positive regulation of transcription, DNA-templated
|
PMID:19661178
|
IDA: Inferred from Direct Assay
|

|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.O46aacf3b6f8a9&page=26540&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="N46aacf4510cc8" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
lsrF 
|

|
PMID:16606699
|
Experiment(s):EBI-1144678 
|-
|
Protein
|
groL 
|

|
PMID:16606699
|
Experiment(s):EBI-1144678 

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.N46aacf4510cc8&page=26540&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="T46a863b3bb4f5" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.T46a863b3bb4f5&page=26540&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="F46aacf46f2728" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=EG12694-MONOMER at EcoCyc]
<pre>MLNSWPLAKD LQVLVEIVHS GSFSAAAATL GQTPAFVTKR IQILENTLAT TLLNRSARGV
ALTESGQRCY EHALEILTQY QRLVDDVTQI KTRPEGMIRI GCSFGFGRSH IAPAITELMR
NYPELQVHFE LFDRQIDLVQ DNIDLDIRIN DEIPDYYIAH LLTKNKRILC AAPEYLQKYP
QPQSLQELSR HDCLVTKERD MTHGIWELGN GQEKKSVKVS GHLSSNSGEI VLQWALEGKG
IMLRSEWDVL PFLESGKLVQ VLPEYAQSAN IWAVYREPLY RSMKLRVCVE FLAAWCQQRL
GKPDEGYQVM</pre>
|-
!align=left {{table heading style}} |Length
||
310
|-
!align=left {{table heading style}} |Mol. Wt
||
35.314 kDa
|-
!align=left {{table heading style}} |pI
||
6.5 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
49,390 - 50,140 (calc based on 11 Y, 6 W, and 6 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.F46aacf46f2728&page=26540&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="O46aacf476f5b6" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
91..297
|
[http://pfam.janelia.org/family/PF03466 PF03466 LysR substrate binding domain]
|

|
PMID:19920124
|-
|
Domain
|
8..67
|
[http://pfam.janelia.org/family/PF00126 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family]
|

|
PMID:19920124

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.O46aacf476f5b6&page=26540&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="A46a863b55abbf" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=ttdR
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P45463 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P45463 PSI-PRED (P45463)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P45463 Genomes TO Protein (P45463)] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.A46a863b55abbf&page=26540&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="H46aacf483b932" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.H46aacf483b932&page=26540&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="E46aacf489b49f" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16130956 GI:16130956]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_417532.1 GeneID:947562]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0010045
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P45463 UniProtKB/Swiss-Prot:P45463]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG12694
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG12694
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=947562 GeneID:947562]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120002359
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB2557
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.E46aacf489b49f&page=26540&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="W46a863b8db5b3" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.W46a863b8db5b3&page=26540&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}

Category:GO:0003700 ! DNA-binding transcription factor activity

2020-07-25T20:59:45Z

Siegele: Created page with "."

Category:GO:0045893 ! positive regulation of transcription, DNA-templated

2020-07-25T20:59:07Z

Siegele: Created page with "."

Category:GO:0001216 ! DNA-binding transcription activator activity

2020-07-25T20:58:55Z

Siegele: Created page with "."

ttdR:Gene Product(s)

2020-07-25T20:57:43Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|ttdR}}{{Tab|Gene|ttdR}}{{Tab On|Gene Product(s)|ttdR}}{{Tab|Expression|ttdR}}{{Tab|Evolution|ttdR}}{{Tab|On One Page|ttdR}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="J46aacf3a5d570" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
TtdR
|-
!align=left {{table heading style}} |Synonyms
||
''predicted DNA-binding transcriptional regulator<ref name='LIB:Riley_2006'/>, TtdR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B3060<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YgiP<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , dan, ECK3050, JW3032, ygiP, b3060''
|-
!align=left {{table heading style}} |Product description
||
predicted DNA-binding transcriptional regulator LYSR-type<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

Transcriptional activator of ttdAB-ygjE, tartrate-inducible; required for tartrate utilization <ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.J46aacf3a5d570&page=26540&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="O46aacf3b6f8a9" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0003700
|
transcription factor activity
|
PMID:15556475
|
ISS: Inferred from Sequence or Structural Similarity
|
Swiss-Prot:P03030
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0003700
|
sequence-specific DNA binding transcription factor activity
|
PMID:16804186
|
IMP: Inferred from Mutant Phenotype
|

|
F
|

|
complete
|-
|

|
GO:0003700
|
transcription factor activity
|
PMID:19661178
|
IDA: Inferred from Direct Assay
|

|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016563
|
transcription activator activity
|
PMID:15556475
|
ISS: Inferred from Sequence or Structural Similarity
|
Swiss-Prot:P03030
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0001216
|
DNA-binding transcription activator activity
|
PMID:16804186
|
IMP: Inferred from Mutant Phenotype
|

|
F
|

|
complete
|-
|

|
GO:0001216
|
DNA-binding transcription activator activity
|
PMID:19661178
|
IDA: Inferred from Direct Assay
|

|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0045893
|
positive regulation of transcription, DNA-templated
|
PMID:15556475
|
ISS: Inferred from Sequence or Structural Similarity
|
Swiss-Prot:P03030

|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0045893
|
positive regulation of transcription, DNA-templated
|
PMID:16804186
|
IMP: Inferred from Mutant Phenotype
|

|
P
|

|
complete
|-
|

|
GO:0045893
|
positive regulation of transcription, DNA-templated
|
PMID:19661178
|
IDA: Inferred from Direct Assay
|

|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.O46aacf3b6f8a9&page=26540&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="N46aacf4510cc8" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
lsrF 
|

|
PMID:16606699
|
Experiment(s):EBI-1144678 
|-
|
Protein
|
groL 
|

|
PMID:16606699
|
Experiment(s):EBI-1144678 

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.N46aacf4510cc8&page=26540&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="T46a863b3bb4f5" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.T46a863b3bb4f5&page=26540&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="F46aacf46f2728" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=EG12694-MONOMER at EcoCyc]
<pre>MLNSWPLAKD LQVLVEIVHS GSFSAAAATL GQTPAFVTKR IQILENTLAT TLLNRSARGV
ALTESGQRCY EHALEILTQY QRLVDDVTQI KTRPEGMIRI GCSFGFGRSH IAPAITELMR
NYPELQVHFE LFDRQIDLVQ DNIDLDIRIN DEIPDYYIAH LLTKNKRILC AAPEYLQKYP
QPQSLQELSR HDCLVTKERD MTHGIWELGN GQEKKSVKVS GHLSSNSGEI VLQWALEGKG
IMLRSEWDVL PFLESGKLVQ VLPEYAQSAN IWAVYREPLY RSMKLRVCVE FLAAWCQQRL
GKPDEGYQVM</pre>
|-
!align=left {{table heading style}} |Length
||
310
|-
!align=left {{table heading style}} |Mol. Wt
||
35.314 kDa
|-
!align=left {{table heading style}} |pI
||
6.5 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
49,390 - 50,140 (calc based on 11 Y, 6 W, and 6 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.F46aacf46f2728&page=26540&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="O46aacf476f5b6" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
91..297
|
[http://pfam.janelia.org/family/PF03466 PF03466 LysR substrate binding domain]
|

|
PMID:19920124
|-
|
Domain
|
8..67
|
[http://pfam.janelia.org/family/PF00126 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family]
|

|
PMID:19920124

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.O46aacf476f5b6&page=26540&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="A46a863b55abbf" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=ttdR
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P45463 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P45463 PSI-PRED (P45463)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P45463 Genomes TO Protein (P45463)] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.A46a863b55abbf&page=26540&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="H46aacf483b932" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.H46aacf483b932&page=26540&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="E46aacf489b49f" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16130956 GI:16130956]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_417532.1 GeneID:947562]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0010045
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P45463 UniProtKB/Swiss-Prot:P45463]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG12694
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG12694
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=947562 GeneID:947562]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120002359
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB2557
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="W46a863b8db5b3" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26540.W46a863b8db5b3&page=26540&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}

ffh:Gene Product(s)

2020-07-25T20:37:20Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|ffh}}{{Tab|Gene|ffh}}{{Tab On|Gene Product(s)|ffh}}{{Tab|Expression|ffh}}{{Tab|Evolution|ffh}}{{Tab|On One Page|ffh}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="T46aab322630a8" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
Ffh
|-
!align=left {{table heading style}} |Synonyms
||
''Signal Recognition Particle (SRP) component with 4.5S RNA (ffs)<ref name='LIB:Riley_2006'/>, B2610<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Ffh<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, P48<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK2607, JW5414, b2610''
|-
!align=left {{table heading style}} |Product description
||
protein component of the signal recognition particle (SRP)<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;

Component of [[:Category:Complex:Signal Recognition Particle Protein Translocation System|Signal Recognition Particle Protein Translocation System]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

Signal Recognition Particle (SRP) protein, with 4.5S RNA; GTPase involved in co-translational protein translocation into and through membranes<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="B46aab323d1e53" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0048500
|
signal recognition particle
|
PMID:1701272
|
IMP: Inferred from Mutant Phenotype
|

|
C
|

|
complete
|-
|

|
GO:0005525
|
GTP binding
|
PMID:7612669
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0006612
|
protein targeting to membrane
|
PMID:1331806
|
IMP: Inferred from Mutant Phenotype
|

|
P
|

|
complete
|-
|

|
GO:1990904
|
ribonucleoprotein complex
|
PMID:1701272
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete
|-
|

|
GO:0048500
|
signal recognition particle
|
PMID:1331806
|
IMP: Inferred from Mutant Phenotype
|

|
C
|

|
complete
|-
|

|
GO:0003723
|
RNA binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0694
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
Contributes to
|
GO:0003924
|
GTPase activity
|
PMID:7612669
|
IDA: Inferred from Direct Assay
|

|
F
|
4.5S RNA
|
complete
|-
|

|
GO:0005515
|
protein binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR013822
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005525
|
GTP binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000897
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005525
|
GTP binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR013822
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005525
|
GTP binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0342
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006614
|
SRP-dependent cotranslational protein targeting to membrane
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004125
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006614
|
SRP-dependent cotranslational protein targeting to membrane
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004780
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006614
|
SRP-dependent cotranslational protein targeting to membrane
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR013822
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008312
|
7S RNA binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004125
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008312
|
7S RNA binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004780
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0017111
|
nucleoside-triphosphatase activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR003593
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25519.B46aab323d1e53&page=25519&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="S46aab329d349d" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
Subunits of [[:Category:Complex:Signal Recognition Particle Protein Translocation System|Signal Recognition Particle Protein Translocation System]]
|
could be indirect
|

|

|-
|
Protein
|
adhE 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
clpA 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
lon 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
metK 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
rplA 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
rplD 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
rplJ 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
rpsB 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
rpsE 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
rpsK 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
tufA 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
rpsD 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
rplJ
|

|
PMID:19402753
|
MALDI(Z-score):18.938026
|-
|
Protein
|
metK
|

|
PMID:19402753
|
MALDI(Z-score):25.833537
|-
|
Protein
|
rpsD
|

|
PMID:19402753
|
MALDI(Z-score):27.913213
|-
|
Protein
|
rplA
|

|
PMID:19402753
|
MALDI(Z-score):27.046126
|-
|
Protein
|
lon
|

|
PMID:19402753
|
MALDI(Z-score):22.248267
|-
|
Protein
|
tufB
|

|
PMID:19402753
|
MALDI(Z-score):22.629013
|-
|
Protein
|
clpA
|

|
PMID:19402753
|
MALDI(Z-score):24.365879
|-
|
RNA
|
4.5S RNA encoded by ffs gene
|
Poritz MA, Bernstein HD, Strub K, Zopf D, Wilhelm H, and Walter P. (1990)
<ref name='PMID:1701272'/>
|

|

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|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="O46a84b03d6609" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25519.O46a84b03d6609&page=25519&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="P46aab32c3902c" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=EG10300-MONOMER at EcoCyc]
<pre>MFDNLTDRLS RTLRNISGRG RLTEDNVKDT LREVRMALLE ADVALPVVRE FINRVKEKAV
GHEVNKSLTP GQEFVKIVRN ELVAAMGEEN QTLNLAAQPP AVVLMAGLQG AGKTTSVGKL
GKFLREKHKK KVLVVSADVY RPAAIKQLET LAEQVGVDFF PSDVGQKPVD IVNAALKEAK
LKFYDVLLVD TAGRLHVDEA MMDEIKQVHA SINPVETLFV VDAMTGQDAA NTAKAFNEAL
PLTGVVLTKV DGDARGGAAL SIRHITGKPI KFLGVGEKTE ALEPFHPDRI ASRILGMGDV
LSLIEDIESK VDRAQAEKLA SKLKKGDGFD LNDFLEQLRQ MKNMGGMASL MGKLPGMGQI
PDNVKSQMDD KVLVRMEAII NSMTMKERAK PEIIKGSRKR RIAAGCGMQV QDVNRLLKQF
DDMQRMMKKM KKGGMAKMMR SMKGMMPPGF PGR</pre>
|-
!align=left {{table heading style}} |Length
||
453
|-
!align=left {{table heading style}} |Mol. Wt
||
49.787 kDa
|-
!align=left {{table heading style}} |pI
||
9.9 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
2,980 - 3,105 (calc based on 2 Y, 0 W, and 1 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25519.P46aab32c3902c&page=25519&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Y46aab32ca84b1" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
100..296
|
[http://pfam.janelia.org/family/PF00448 PF00448 SRP54-type protein, GTPase domain]
|

|
PMID:19920124
|-
|
Domain
|
5..82
|
[http://pfam.janelia.org/family/PF02881 PF02881 SRP54-type protein, helical bundle domain]
|

|
PMID:19920124
|-
|
Domain
|
328..427
|
[http://pfam.janelia.org/family/PF02978 PF02978 Signal peptide binding domain]
|

|
PMID:19920124

|- class="tableEdit_footer"
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|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="W46aab32d1226c" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=ffh
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P0AGD7 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P0AGD7 PSI-PRED (P0AGD7)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P0AGD7 Genomes TO Protein (P0AGD7)] (GTOP)

|- class="tableEdit_footer"
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|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="V46aab32e86c10" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25519.V46aab32e86c10&page=25519&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="G46aab32ee570b" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16130531 GI:16130531]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_417101.1 GeneID:947102]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0008586
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P0AGD7 UniProtKB/Swiss-Prot:P0AGD7]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG10300
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG10300
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=947102 GeneID:947102]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120000294
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB0296
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="O46a84b0bc7016" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25519.O46a84b0bc7016&page=25519&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:RefGenome_Annotated_Gene]]

Category:GO:1990904 ! ribonucleoprotein complex

2020-07-25T20:36:19Z

Siegele: Created page with "."

ffh:Gene Product(s)

2020-07-24T01:55:33Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|ffh}}{{Tab|Gene|ffh}}{{Tab On|Gene Product(s)|ffh}}{{Tab|Expression|ffh}}{{Tab|Evolution|ffh}}{{Tab|On One Page|ffh}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="T46aab322630a8" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
Ffh
|-
!align=left {{table heading style}} |Synonyms
||
''Signal Recognition Particle (SRP) component with 4.5S RNA (ffs)<ref name='LIB:Riley_2006'/>, B2610<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Ffh<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, P48<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK2607, JW5414, b2610''
|-
!align=left {{table heading style}} |Product description
||
protein component of the signal recognition particle (SRP)<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;

Component of [[:Category:Complex:Signal Recognition Particle Protein Translocation System|Signal Recognition Particle Protein Translocation System]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

Signal Recognition Particle (SRP) protein, with 4.5S RNA; GTPase involved in co-translational protein translocation into and through membranes<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="B46aab323d1e53" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0048500
|
signal recognition particle
|
PMID:1701272
|
IMP: Inferred from Mutant Phenotype
|

|
C
|

|
complete
|-
|

|
GO:0005525
|
GTP binding
|
PMID:7612669
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0006612
|
protein targeting to membrane
|
PMID:1331806
|
IMP: Inferred from Mutant Phenotype
|

|
P
|

|
complete
|-
|

|
GO:1990904
|
ribonucleoprotein complex
|
PMID:1701272
|
IDA: Inferred from Direct Assay
|

|
C
|
GO:1990904
|
complete
|-
|

|
GO:0048500
|
signal recognition particle
|
PMID:1331806
|
IMP: Inferred from Mutant Phenotype
|

|
C
|

|
complete
|-
|

|
GO:0003723
|
RNA binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0694
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
Contributes to
|
GO:0003924
|
GTPase activity
|
PMID:7612669
|
IDA: Inferred from Direct Assay
|

|
F
|
4.5S RNA
|
complete
|-
|

|
GO:0005515
|
protein binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR013822
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005525
|
GTP binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000897
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005525
|
GTP binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR013822
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005525
|
GTP binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0342
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006614
|
SRP-dependent cotranslational protein targeting to membrane
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004125
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006614
|
SRP-dependent cotranslational protein targeting to membrane
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004780
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006614
|
SRP-dependent cotranslational protein targeting to membrane
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR013822
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008312
|
7S RNA binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004125
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008312
|
7S RNA binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004780
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0017111
|
nucleoside-triphosphatase activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR003593
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25519.B46aab323d1e53&page=25519&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="S46aab329d349d" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
Subunits of [[:Category:Complex:Signal Recognition Particle Protein Translocation System|Signal Recognition Particle Protein Translocation System]]
|
could be indirect
|

|

|-
|
Protein
|
adhE 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
clpA 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
lon 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
metK 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
rplA 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
rplD 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
rplJ 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
rpsB 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
rpsE 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
rpsK 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
tufA 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
rpsD 
|

|
PMID:15690043
|
Experiment(s):EBI-880876 
|-
|
Protein
|
rplJ
|

|
PMID:19402753
|
MALDI(Z-score):18.938026
|-
|
Protein
|
metK
|

|
PMID:19402753
|
MALDI(Z-score):25.833537
|-
|
Protein
|
rpsD
|

|
PMID:19402753
|
MALDI(Z-score):27.913213
|-
|
Protein
|
rplA
|

|
PMID:19402753
|
MALDI(Z-score):27.046126
|-
|
Protein
|
lon
|

|
PMID:19402753
|
MALDI(Z-score):22.248267
|-
|
Protein
|
tufB
|

|
PMID:19402753
|
MALDI(Z-score):22.629013
|-
|
Protein
|
clpA
|

|
PMID:19402753
|
MALDI(Z-score):24.365879
|-
|
RNA
|
4.5S RNA encoded by ffs gene
|
Poritz MA, Bernstein HD, Strub K, Zopf D, Wilhelm H, and Walter P. (1990)
<ref name='PMID:1701272'/>
|

|

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|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="O46a84b03d6609" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes

|- class="tableEdit_footer"
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|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="P46aab32c3902c" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=EG10300-MONOMER at EcoCyc]
<pre>MFDNLTDRLS RTLRNISGRG RLTEDNVKDT LREVRMALLE ADVALPVVRE FINRVKEKAV
GHEVNKSLTP GQEFVKIVRN ELVAAMGEEN QTLNLAAQPP AVVLMAGLQG AGKTTSVGKL
GKFLREKHKK KVLVVSADVY RPAAIKQLET LAEQVGVDFF PSDVGQKPVD IVNAALKEAK
LKFYDVLLVD TAGRLHVDEA MMDEIKQVHA SINPVETLFV VDAMTGQDAA NTAKAFNEAL
PLTGVVLTKV DGDARGGAAL SIRHITGKPI KFLGVGEKTE ALEPFHPDRI ASRILGMGDV
LSLIEDIESK VDRAQAEKLA SKLKKGDGFD LNDFLEQLRQ MKNMGGMASL MGKLPGMGQI
PDNVKSQMDD KVLVRMEAII NSMTMKERAK PEIIKGSRKR RIAAGCGMQV QDVNRLLKQF
DDMQRMMKKM KKGGMAKMMR SMKGMMPPGF PGR</pre>
|-
!align=left {{table heading style}} |Length
||
453
|-
!align=left {{table heading style}} |Mol. Wt
||
49.787 kDa
|-
!align=left {{table heading style}} |pI
||
9.9 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
2,980 - 3,105 (calc based on 2 Y, 0 W, and 1 C residues)

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|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Y46aab32ca84b1" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
100..296
|
[http://pfam.janelia.org/family/PF00448 PF00448 SRP54-type protein, GTPase domain]
|

|
PMID:19920124
|-
|
Domain
|
5..82
|
[http://pfam.janelia.org/family/PF02881 PF02881 SRP54-type protein, helical bundle domain]
|

|
PMID:19920124
|-
|
Domain
|
328..427
|
[http://pfam.janelia.org/family/PF02978 PF02978 Signal peptide binding domain]
|

|
PMID:19920124

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|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="W46aab32d1226c" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=ffh
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P0AGD7 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P0AGD7 PSI-PRED (P0AGD7)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P0AGD7 Genomes TO Protein (P0AGD7)] (GTOP)

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|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="V46aab32e86c10" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="G46aab32ee570b" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16130531 GI:16130531]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_417101.1 GeneID:947102]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0008586
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P0AGD7 UniProtKB/Swiss-Prot:P0AGD7]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG10300
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG10300
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=947102 GeneID:947102]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120000294
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB0296
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

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<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="O46a84b0bc7016" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

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|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:RefGenome_Annotated_Gene]]

Category:GO:0030529 ! intracellular ribonucleoprotein complex

2020-07-24T01:52:35Z

Siegele: Created page with "."

sixA:Gene Product(s)

2020-07-24T01:51:38Z

Siegele: Table edited by $2 via TableEdit

setB:Gene Product(s)

2020-07-24T01:49:22Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|setB}}{{Tab|Gene|setB}}{{Tab On|Gene Product(s)|setB}}{{Tab|Expression|setB}}{{Tab|Evolution|setB}}{{Tab|On One Page|setB}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="F46aa96150a6ee" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
SetB
|-
!align=left {{table heading style}} |Synonyms
||
''lactose/glucose efflux system<ref name='LIB:Riley_2006'/>, B2170<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YeiO<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SetB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK2163, JW2157, yeiO, b2170''
|-
!align=left {{table heading style}} |Product description
||
SetB MFS transporter<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

Glucose and lactose efflux transporter<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="R46aa961618766" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0997
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-1003
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016020
|
membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0472
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0007059
|
chromosome segregation
|
PMID:14617174
|
IMP: Inferred from Mutant Phenotype
|

|
P
|

|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004750
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016020
|
membrane
|
PMID:14617174
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0812
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0015767
|
lactose transport
|
PMID:10438463
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0005351
|
carbohydrate:proton symporter activity
|
PMID:10438463
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GO_REF:0000023
|
IEA: Inferred from Electronic Annotation
|
SP_SL:SL-9909
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0015758
|
glucose transport
|
PMID:10438463
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0055085
|
transmembrane transport
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011701
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016020
|
membrane
|
PMID:10438463
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.24504.R46aa961618766&page=24504&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="X46aa961c3ed98" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
MreB
|

|
PMID:14617174
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.24504.X46aa961c3ed98&page=24504&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Y46a829e61f2bf" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-
|
plasma membrane
|
C-terminus localized in the cytoplasm with 12 predicted transmembrane domains
|
Daley et al. (2005) <ref name=PMID:15919996/>
|

|

|- class="tableEdit_footer"
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|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="S46aa961e256ca" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=B2170-MONOMER at EcoCyc]
<pre>MHNSPAVSSA KSFDLTSTAF LIVAFLTGIA GALQTPTLSI FLTDEVHARP AMVGFFFTGS
AVIGILVSQF LAGRSDKRGD RKSLIVFCCL LGVLACTLFA WNRNYFVLLF VGVFLSSFGS
TANPQMFALA REHADKTGRE AVMFSSFLRA QVSLAWVIGP PLAYALAMGF SFTVMYLSAA
VAFIVCGVMV WLFLPSMRKE LPLATGTIEA PRRNRRDTLL LFVICTLMWG SNSLYIINMP
LFIINELHLP EKLAGVMMGT AAGLEIPTML IAGYFAKRLG KRFLMRVAAV GGVCFYAGML
MAHSPVILLG LQLLNAIFIG ILGGIGMLYF QDLMPGQAGS ATTLYTNTSR VGWIIAGSVA
GIVAEIWNYH AVFWFAMVMI IATLFCLLRI KDV</pre>
|-
!align=left {{table heading style}} |Length
||
393
|-
!align=left {{table heading style}} |Mol. Wt
||
42.747 kDa
|-
!align=left {{table heading style}} |pI
||
10.1 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
51,910 - 52,785 (calc based on 9 Y, 7 W, and 7 C residues)

|- class="tableEdit_footer"
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|}


<big>'''Domains/Motifs/Modification Sites'''</big>
<table>
<tr align="left" valign="top">
<td>


{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="A46aa961e92aca" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
20..357
|
[http://pfam.janelia.org/family/PF07690 PF07690 Major Facilitator Superfamily]
|

|
PMID:19920124

|- class="tableEdit_footer"
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|}


</td>
<td>


<motif_map/>
{{TMHMM Picture|setB}}
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="C46a829e7da953" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=setB
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P33026 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P33026 PSI-PRED (P33026)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P33026 Genomes TO Protein (P33026)] (GTOP)

|- class="tableEdit_footer"
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|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="W46aa961f587ac" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.24504.W46aa961f587ac&page=24504&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="R46aa961fb527b" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16130108 GI:16130108]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_416675.1 GeneID:946673]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0007184
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P33026 UniProtKB/Swiss-Prot:P33026]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG12034
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG12034
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=946673 GeneID:946673]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120001951
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB1969
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="T46a829ebbf755" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.24504.T46a829ebbf755&page=24504&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

Category:GO:0032991 ! protein-containing complex

2020-07-24T01:47:09Z

Siegele: Created page with "."

folE:Gene Product(s)

2020-07-24T01:45:30Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|folE}}{{Tab|Gene|folE}}{{Tab On|Gene Product(s)|folE}}{{Tab|Expression|folE}}{{Tab|Evolution|folE}}{{Tab|On One Page|folE}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="F46aa94ff25f8a" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
FolE
|-
!align=left {{table heading style}} |Synonyms
||
''GTP cyclohydrolase I<ref name='LIB:Riley_2006'/>, B2153<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, FolE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK2146, JW2140, b2153''
|-
!align=left {{table heading style}} |Product description
||
GTP cyclohydrolase I<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;

Component of [[:Category:Complex:GTP cyclohydrolase I|GTP cyclohydrolase I]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

GTP cyclohydrolase I<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.16 3.5.4.16]<ref name='LIB:Riley_2006'/>

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.24465.F46aa94ff25f8a&page=24465&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="O46aa95008d495" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0005737
|
cytoplasm
|
PMID:821948
|
IDA: Inferred from Direct Assay
|

|
C
|
FolE was present in the supernatant after subcellular fractionation.

Seeded from Riley et al 2006 <ref name='LIB:Riley_2006'/>.
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|
PMID:4296838
|
IDA: Inferred from Direct Assay
|

|
C
|
GTP cyclohyrdolase I activity was purified from the supernatant after subcellular fractionation.
|
complete
|-
|

|
GO:0003934
|
GTP cyclohydrolase I activity
|
GOA:hamap GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_00223
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0003934
|
GTP cyclohydrolase I activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001474
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005525
|
GTP binding
|
PMID:821948
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0003934
|
GTP cyclohydrolase I activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR018234
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0032991
|
protein-containing complex
|
PMID:821948
|
IDA: Inferred from Direct Assay
|

|
C
|
Based on biochemical characterization.
|
complete
|-
|

|
GO:0003934
|
GTP cyclohydrolase I activity
|
GOA:spec GO_REF:0000003
|
IEA: Inferred from Electronic Annotation
|
EC:3.5.4.16
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0032991
|
protein-containing complex
|
PMID:7663943
|
IDA: Inferred from Direct Assay
|

|
C
|
FolE is a homodecamer based on X-ray crystallography.
|
complete
|-
|

|
GO:0005525
|
GTP binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0342
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006730
|
one-carbon metabolic process
|
GOA:hamap GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_00223
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006730
|
one-carbon metabolic process
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0554
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008270
|
zinc ion binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0862
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0046654
|
tetrahydrofolate biosynthetic process
|
GOA:hamap GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_00223
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0046654
|
tetrahydrofolate biosynthetic process
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001474
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0046654
|
tetrahydrofolate biosynthetic process
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR018234
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.24465.O46aa95008d495&page=24465&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Y46aa950aa2965" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
Subunits of [[:Category:Complex:GTP cyclohydrolase I|GTP cyclohydrolase I]]
|
could be indirect
|

|

|- class="tableEdit_footer"
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|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="V46a828d386f82" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.24465.V46a828d386f82&page=24465&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="Q46aa950d01976" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=GTP-CYCLOHYDRO-I-MONOMER at EcoCyc]
<pre>MPSLSKEAAL VHEALVARGL ETPLRPPVHE MDNETRKSLI AGHMTEIMQL LNLDLADDSL
METPHRIAKM YVDEIFSGLD YANFPKITLI ENKMKVDEMV TVRDITLTST CEHHFVTIDG
KATVAYIPKD SVIGLSKINR IVQFFAQRPQ VQERLTQQIL IALQTLLGTN NVAVSIDAVH
YCVKARGIRD ATSATTTTSL GGLFKSSQNT RHEFLRAVRH HN</pre>
|-
!align=left {{table heading style}} |Length
||
222
|-
!align=left {{table heading style}} |Mol. Wt
||
24.83 kDa
|-
!align=left {{table heading style}} |pI
||
7.4 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
5,960 - 6,210 (calc based on 4 Y, 0 W, and 2 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.24465.Q46aa950d01976&page=24465&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="N46aa950d6ef46" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Initiator Methionine
|
1
|
Removed
|
[http://www.uniprot.org/uniprot/P0A6T5#section_features UniProt:P0A6T5]
|

|-
|
Domain
|
117..202
|
[http://pfam.janelia.org/family/PF01227 PF01227 GTP cyclohydrolase I]
|

|
PMID:19920124

|- class="tableEdit_footer"
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|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="J46aa950dcb3ea" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=folE
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P0A6T5 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P0A6T5 PSI-PRED (P0A6T5)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P0A6T5 Genomes TO Protein (P0A6T5)] (GTOP)

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</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="L46aa951323fee" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

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<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Z46aa951380e00" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16130091 GI:16130091]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_416658.1 GeneID:949040]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0007117
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P0A6T5 UniProtKB/Swiss-Prot:P0A6T5]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG11375
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG11375
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=949040 GeneID:949040]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120001343
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB1349
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

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<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


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|- {{table_heading_style}}
!|Name!!URL!!Comments

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|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

thrS:Gene Product(s)

2020-07-24T01:38:17Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|thrS}}{{Tab|Gene|thrS}}{{Tab On|Gene Product(s)|thrS}}{{Tab|Expression|thrS}}{{Tab|Evolution|thrS}}{{Tab|On One Page|thrS}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="O46aa798403485" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
ThrS
|-
!align=left {{table heading style}} |Synonyms
||
''threonyl-tRNA synthetase<ref name='LIB:Riley_2006'/>, B1719<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ThrS<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK1717, JW1709, b1719''
|-
!align=left {{table heading style}} |Product description
||
threonyl-tRNA synthetase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;

Component of [[:Category:Complex:threonyl-tRNA synthetase|threonyl-tRNA synthetase]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

Threonine--tRNA ligase, autogenously regulated; binds Zn(II)<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.3 6.1.1.3]<ref name='LIB:Riley_2006'/>

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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="P46aa79857b482" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0005524
|
ATP binding
|
PMID:10319817
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0003723
|
RNA binding
|
PMID:10319817
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0008270
|
zinc ion binding
|
PMID:10319817
|
IMP: Inferred from Mutant Phenotype
|

|
F
|

|
complete
|-
|

|
GO:0005515
|
protein binding
|
PMID:10319817
|
IPI: Inferred from Physical Interaction
|
EcoliWiki:thrS
|
F
|
ThrRS is a homodimer of thrS gene products.
|
complete
|-
|

|
GO:0000166
|
nucleotide binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0547
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006435
|
threonyl-tRNA aminoacylation
|
PMID:330505
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0003723
|
RNA binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0694
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|
PMID:330505
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete
|-
|

|
GO:0004812
|
aminoacyl-tRNA ligase activity
|
PMID:330505
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0004829
|
threonine-tRNA ligase activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR018158
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0043039
|
tRNA aminoacylation
|
PMID:330505
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0006418
|
tRNA aminoacylation for protein translation
|
PMID:330505
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0004829
|
threonine-tRNA ligase activity
|
GOA:spec GO_REF:0000003
|
IEA: Inferred from Electronic Annotation
|
EC:6.1.1.3
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005515
|
protein binding
|
PMID:10319817
|
IPI: Inferred from Physical Interaction
|
EcoliWiki:thrS
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GOA:hamap GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_00184
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR002314
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR002320
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004154
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR006195
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR012947
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR018158
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0067
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|
GOA:hamap GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_00184
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR002314
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR002320
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR012947
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR018158
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0963
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|
GO_REF:0000023
|
IEA: Inferred from Electronic Annotation
|
SP_SL:SL-0086
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006435
|
threonyl-tRNA aminoacylation
|
GOA:hamap GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_00184
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006435
|
threonyl-tRNA aminoacylation
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR002320
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006435
|
threonyl-tRNA aminoacylation
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR018158
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete

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|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.23508.P46aa79857b482&page=23508&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="W46aa79b6039e3" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
Subunits of [[:Category:Complex:threonyl-tRNA synthetase|threonyl-tRNA synthetase]]
|
could be indirect
|

|

|-
|
Protein
|
rplA 
|

|
PMID:15690043
|
Experiment(s):EBI-879795, EBI-884548 
|-
|
Protein
|
dnaK 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
eno 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
ibpA 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
rpe 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
rplC 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
rplI 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
rplM 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
rplS 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
rplV 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
rpsA 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
rpsB 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
rpsE 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
rpsF 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
rpsG 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
rpsJ 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
rpsM 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
rpsN 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
rpsT 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
wcaB 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
yhbY 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
yicC 
|

|
PMID:15690043
|
Experiment(s):EBI-884548 
|-
|
Protein
|
recR 
|

|
PMID:16606699
|
Experiment(s):EBI-1140596 
|-
|
Protein
|
nadE 
|

|
PMID:16606699
|
Experiment(s):EBI-1140596 
|-
|
Protein
|
rpsC 
|

|
PMID:16606699
|
Experiment(s):EBI-1140596 
|-
|
Protein
|
yggM 
|

|
PMID:16606699
|
Experiment(s):EBI-1140596 
|-
|
Protein
|
rpsM
|

|
PMID:19402753
|
LCMS(ID Probability):99.0 MALDI(Z-score):3.070866
|-
|
Protein
|
rplS
|

|
PMID:19402753
|
LCMS(ID Probability):99.0 MALDI(Z-score):3.739354
|-
|
Protein
|
rplA
|

|
PMID:19402753
|
LCMS(ID Probability):99.0 MALDI(Z-score):10.739046
|-
|
Protein
|
eno
|

|
PMID:19402753
|
LCMS(ID Probability):99.6
|-
|
Protein
|
rpe
|

|
PMID:19402753
|
LCMS(ID Probability):99.6
|-
|
Protein
|
ibpA
|

|
PMID:19402753
|
LCMS(ID Probability):99.6
|-
|
Protein
|
yicC
|

|
PMID:19402753
|
LCMS(ID Probability):99.6
|-
|
Protein
|
wcaB
|

|
PMID:19402753
|
LCMS(ID Probability):99.0
|-
|
Small Molecule
|
Borrelidin
|

|
PMID:330505
|
See figure 4.

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|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="E46a80b308026f" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes

|- class="tableEdit_footer"
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|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="T46aa79b874277" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=THRS-MONOMER at EcoCyc]
<pre>MPVITLPDGS QRHYDHAVSP MDVALDIGPG LAKACIAGRV NGELVDACDL IENDAQLSII
TAKDEEGLEI IRHSCAHLLG HAIKQLWPHT KMAIGPVIDN GFYYDVDLDR TLTQEDVEAL
EKRMHELAEK NYDVIKKKVS WHEARETFAN RGESYKVSIL DENIAHDDKP GLYFHEEYVD
MCRGPHVPNM RFCHHFKLMK TAGAYWRGDS NNKMLQRIYG TAWADKKALN AYLQRLEEAA
KRDHRKIGKQ LDLYHMQEEA PGMVFWHNDG WTIFRELEVF VRSKLKEYQY QEVKGPFMMD
RVLWEKTGHW DNYKDAMFTT SSENREYCIK PMNCPGHVQI FNQGLKSYRD LPLRMAEFGS
CHRNEPSGSL HGLMRVRGFT QDDAHIFCTE EQIRDEVNGC IRLVYDMYST FGFEKIVVKL
STRPEKRIGS DEMWDRAEAD LAVALEENNI PFEYQLGEGA FYGPKIEFTL YDCLDRAWQC
GTVQLDFSLP SRLSASYVGE DNERKVPVMI HRAILGSMER FIGILTEEFA GFFPTWLAPV
QVVIMNITDS QSEYVNELTQ KLSNAGIRVK ADLRNEKIGF KIREHTLRRV PYMLVCGDKE
VESGKVAVRT RRGKDLGSMD VNEVIEKLQQ EIRSRSLKQL EE</pre>
|-
!align=left {{table heading style}} |Length
||
642
|-
!align=left {{table heading style}} |Mol. Wt
||
74.014 kDa
|-
!align=left {{table heading style}} |pI
||
6.1 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
96,260 - 97,885 (calc based on 24 Y, 11 W, and 13 C residues)

|- class="tableEdit_footer"
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|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="O46aa79b8e8f1d" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
541..631
|
[http://pfam.janelia.org/family/PF03129 PF03129 Anticodon binding domain]
|

|
PMID:19920124
|-
|
Domain
|
1..61
|
[http://pfam.janelia.org/family/PF02824 PF02824 TGS domain]
|

|
PMID:19920124
|-
|
Domain
|
273..440
|
[http://pfam.janelia.org/family/PF00587 PF00587 tRNA synthetase class II core domain (G, H, P, S and T)]
|

|
PMID:19920124
|-
|
Domain
|
171..219
|
[http://pfam.janelia.org/family/PF07973 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain]
|

|
PMID:19920124

|- class="tableEdit_footer"
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|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="D46aa79b954eab" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=thrS
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P0A8M3 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P0A8M3 PSI-PRED (P0A8M3)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P0A8M3 Genomes TO Protein (P0A8M3)] (GTOP)

|- class="tableEdit_footer"
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|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="C46aa79c14be53" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.23508.C46aa79c14be53&page=23508&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="X46aa79c1a9feb" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16129675 GI:16129675]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_416234.1 GeneID:946222]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0005736
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P0A8M3 UniProtKB/Swiss-Prot:P0A8M3]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG11001
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG11001
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=946222 GeneID:946222]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120000990
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB0994
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="M46a80b3d94847" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.23508.M46a80b3d94847&page=23508&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

Category:GO:0015420 ! ATPase-coupled cobalamin transmembrane transporter activity

2020-07-22T22:59:50Z

Siegele: Created page with "."

btuC:Gene Product(s)

2020-07-22T22:59:30Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|btuC}}{{Tab|Gene|btuC}}{{Tab On|Gene Product(s)|btuC}}{{Tab|Expression|btuC}}{{Tab|Evolution|btuC}}{{Tab|On One Page|btuC}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="J46aa788e031c0" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
BtuC
|-
!align=left {{table heading style}} |Synonyms
||
''vitamin B12 transporter subunit: membrane component of ABC superfamily<ref name='LIB:Riley_2006'/>, B1711<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, BtuC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK1709, JW1701, b1711''
|-
!align=left {{table heading style}} |Product description
||
BtuC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;

Component of [[:Category:Complex:vitamin B12 ABC transporter|vitamin B12 ABC transporter]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>; [[:Category:Complex:vitamin B12 transport system|vitamin B12 transport system]]<ref name='LIB:EcoCyc11.1'/>

B12 uptake, ABC transporter ATPase<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Y46aa788fede3e" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:hamap GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_01004
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0997
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-1003
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0015889
|
cobalamin transport
|
PMID:3528128
|
IMP: Inferred from Mutant Phenotype
|

|
P
|

|
complete
|-
|

|
GO:0016020
|
membrane
|
PMID:3528128
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete
|-
|

|
GO:0015889
|
cobalamin transport
|
GOA:hamap GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_01004
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016020
|
membrane
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000522
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016020
|
membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0472
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0812
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GO_REF:0000023
|
IEA: Inferred from Electronic Annotation
|
SP_SL:SL-9909
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005887
|
integral to plasma membrane
|
PMID:3528129
|
ISM: Inferred from Sequence Model
|
PMID:3986213
PMID:7108955

|
C
|
text on pg. 932
|
complete
|-
|

|
GO:0015420
|
ATPase-coupled cobalamin transmembrane transporter activity
|
PMID:6768753
|
IMP: Inferred from Mutant Phenotype
|

|
F
|
Fig. 1
|
complete

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.23485.Y46aa788fede3e&page=23485&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="O46aa78932c9de" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
Subunits of [[:Category:Complex:vitamin B12 ABC transporter|vitamin B12 ABC transporter]]
|
could be indirect
|

|

|-
|
Protein
|
Subunits of [[:Category:Complex:vitamin B12 transport system|vitamin B12 transport system]]
|
could be indirect
|

|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.23485.O46aa78932c9de&page=23485&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="G46aa789501efa" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-
|
plasma membrane
|
C-terminus localized in the cytoplasm with 8 predicted transmembrane domains
|
Daley et al. (2005) <ref name=PMID:15919996/>
|

|

|-
|
plasma membrane
|

|

|

|

|- class="tableEdit_footer"
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|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="D46aa78969ef21" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=BTUC-MONOMER at EcoCyc]
<pre>MLTLARQQQR QNIRWLLCLS VLMLLALLLS LCAGEQWISP GDWFTPRGEL FVWQIRLPRT
LAVLLVGAAL AISGAVMQAL FENPLAEPGL LGVSNGAGVG LIAAVLLGQG QLPNWALGLC
AIAGALIITL ILLRFARRHL STSRLLLAGV ALGIICSALM TWAIYFSTSV DLRQLMYWMM
GGFGGVDWRQ SWLMLALIPV LLWICCQSRP MNMLALGEIS ARQLGLPLWF WRNVLVAATG
WMVGVSVALA GAIGFIGLVI PHILRLCGLT DHRVLLPGCA LAGASALLLA DIVARLALAA
AELPIGVVTA TLGAPVFIWL LLKAGR</pre>
|-
!align=left {{table heading style}} |Length
||
326
|-
!align=left {{table heading style}} |Mol. Wt
||
34.95 kDa
|-
!align=left {{table heading style}} |pI
||
9.8 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
79,980 - 80,980 (calc based on 2 Y, 14 W, and 8 C residues)

|- class="tableEdit_footer"
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|}


<big>'''Domains/Motifs/Modification Sites'''</big>
<table>
<tr align="left" valign="top">
<td>


{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="L46aa7897162e7" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
22..323
|
[http://pfam.janelia.org/family/PF01032 PF01032 FecCD transport family]
|

|
PMID:19920124

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.23485.L46aa7897162e7&page=23485&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}


</td>
<td>


<motif_map/>
{{TMHMM Picture|btuC}}
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="O46aa78977d410" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=btuC
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P06609 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P06609 PSI-PRED (P06609)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P06609 Genomes TO Protein (P06609)] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.23485.O46aa78977d410&page=23485&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="S46aa78985c393" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.23485.S46aa78985c393&page=23485&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="O46aa7898b96fe" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16129667 GI:16129667]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_416226.1 GeneID:945877]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0005712
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P06609 UniProtKB/Swiss-Prot:P06609]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG10127
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG10127
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=945877 GeneID:945877]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120000123
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB0125
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.23485.O46aa7898b96fe&page=23485&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="H46a80a21defa9" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

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|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

setA:Gene Product(s)

2020-07-22T22:57:03Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|setA}}{{Tab|Gene|setA}}{{Tab On|Gene Product(s)|setA}}{{Tab|Expression|setA}}{{Tab|Evolution|setA}}{{Tab|On One Page|setA}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="I46aa19999383d" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
SetA
|-
!align=left {{table heading style}} |Synonyms
||
''broad specificity sugar efflux system<ref name='LIB:Riley_2006'/>, B0070<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SetA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YabM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0072, JW0069, yabM, b0070''
|-
!align=left {{table heading style}} |Product description
||
YabM MFS transporter<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

Broad specificity sugar efflux transporter<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.I46aa19999383d&page=19610&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="X46aa199a8b148" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0997
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-1003
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005351
|
carbohydrate:proton symporter activity
|
*GOA:interpro
*GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|

|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016020
|
membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0472
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004750
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0812
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0015767
|
lactose transport
|
PMID:10438463
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GO_REF:0000023
|
IEA: Inferred from Electronic Annotation
|
SP_SL:SL-9909
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:1904659
|
glucose transmembrane transport
|
PMID:10438463
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0016020
|
membrane
|
PMID:10438463
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.X46aa199a8b148&page=19610&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Z46aa199fd1994" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.Z46aa199fd1994&page=19610&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="V46a72f5fcbb90" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-
|
plasma membrane
|
C-terminus localized in the cytoplasm with 12 predicted transmembrane domains
|
Daley et al. (2005) <ref name=PMID:15919996/>
|

|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.V46a72f5fcbb90&page=19610&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="S46aa19a1960ec" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=B0070-MONOMER at EcoCyc]
<pre>MIWIMTMARR MNGVYAAFML VAFMMGVAGA LQAPTLSLFL SREVGAQPFW IGLFYTVNAI
AGIGVSLWLA KRSDSQGDRR KLIIFCCLMA IGNALLFAFN RHYLTLITCG VLLASLANTA
MPQLFALARE YADNSAREVV MFSSVMRAQL SLAWVIGPPL AFMLALNYGF TVMFSIAAGI
FTLSLVLIAF MLPSVARVEL PSENALSMQG GWQDSNVRML FVASTLMWTC NTMYIIDMPL
WISSELGLPD KLAGFLMGTA AGLEIPAMIL AGYYVKRYGK RRMMVIAVAA GVLFYTGLIF
FNSRMALMTL QLFNAVFIGI VAGIGMLWFQ DLMPGRAGAA TTLFTNSIST GVILAGVIQG
AIAQSWGHFA VYWVIAVISV VALFLTAKVK DV</pre>
|-
!align=left {{table heading style}} |Length
||
392
|-
!align=left {{table heading style}} |Mol. Wt
||
42.714 kDa
|-
!align=left {{table heading style}} |pI
||
9.9 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
71,390 - 71,890 (calc based on 11 Y, 10 W, and 4 C residues)

|- class="tableEdit_footer"
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|}


<big>'''Domains/Motifs/Modification Sites'''</big>
<table>
<tr align="left" valign="top">
<td>


{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="F46aa19a1ee469" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
18..345
|
[http://pfam.janelia.org/family/PF07690 PF07690 Major Facilitator Superfamily]
|

|
PMID:19920124

|- class="tableEdit_footer"
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|}


</td>
<td>


<motif_map/>
{{TMHMM Picture|setA}}
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="U46a72f614ccd9" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=setA
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P31675 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P31675 PSI-PRED (P31675)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P31675 Genomes TO Protein (P31675)] (GTOP)

|- class="tableEdit_footer"
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|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="X46aa19a28cd06" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.X46aa19a28cd06&page=19610&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Z46aa19a2d5943" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/49175994 GI:49175994]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/YP_025293.1 GeneID:944793]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0000257
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P31675 UniProtKB/Swiss-Prot:P31675]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG11754
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG11754
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=944793 GeneID:944793]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120001692
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB1704
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="B46a72f645e9c6" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
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|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

Category:GO:0005351 ! carbohydrate:proton symporter activity

2020-07-22T22:56:29Z

Siegele: Created page with "."

Category:GO:1904659 ! glucose transmembrane transport

2020-07-22T22:56:12Z

Siegele: Created page with "."

setA:Gene Product(s)

2020-07-22T22:55:50Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|setA}}{{Tab|Gene|setA}}{{Tab On|Gene Product(s)|setA}}{{Tab|Expression|setA}}{{Tab|Evolution|setA}}{{Tab|On One Page|setA}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="I46aa19999383d" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
SetA
|-
!align=left {{table heading style}} |Synonyms
||
''broad specificity sugar efflux system<ref name='LIB:Riley_2006'/>, B0070<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SetA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YabM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0072, JW0069, yabM, b0070''
|-
!align=left {{table heading style}} |Product description
||
YabM MFS transporter<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

Broad specificity sugar efflux transporter<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="X46aa199a8b148" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0997
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-1003
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005351
|
carbohydrate:proton symporter activity
|
*GOA:interpro
*GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|

|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016020
|
membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0472
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004750
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0812
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0015767
|
lactose transport
|
PMID:10438463
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GO_REF:0000023
|
IEA: Inferred from Electronic Annotation
|
SP_SL:SL-9909
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:1904659
|
glucose transport
|
PMID:10438463
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0016020
|
membrane
|
PMID:10438463
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.X46aa199a8b148&page=19610&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Z46aa199fd1994" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.Z46aa199fd1994&page=19610&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="V46a72f5fcbb90" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-
|
plasma membrane
|
C-terminus localized in the cytoplasm with 12 predicted transmembrane domains
|
Daley et al. (2005) <ref name=PMID:15919996/>
|

|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.V46a72f5fcbb90&page=19610&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="S46aa19a1960ec" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=B0070-MONOMER at EcoCyc]
<pre>MIWIMTMARR MNGVYAAFML VAFMMGVAGA LQAPTLSLFL SREVGAQPFW IGLFYTVNAI
AGIGVSLWLA KRSDSQGDRR KLIIFCCLMA IGNALLFAFN RHYLTLITCG VLLASLANTA
MPQLFALARE YADNSAREVV MFSSVMRAQL SLAWVIGPPL AFMLALNYGF TVMFSIAAGI
FTLSLVLIAF MLPSVARVEL PSENALSMQG GWQDSNVRML FVASTLMWTC NTMYIIDMPL
WISSELGLPD KLAGFLMGTA AGLEIPAMIL AGYYVKRYGK RRMMVIAVAA GVLFYTGLIF
FNSRMALMTL QLFNAVFIGI VAGIGMLWFQ DLMPGRAGAA TTLFTNSIST GVILAGVIQG
AIAQSWGHFA VYWVIAVISV VALFLTAKVK DV</pre>
|-
!align=left {{table heading style}} |Length
||
392
|-
!align=left {{table heading style}} |Mol. Wt
||
42.714 kDa
|-
!align=left {{table heading style}} |pI
||
9.9 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
71,390 - 71,890 (calc based on 11 Y, 10 W, and 4 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.S46aa19a1960ec&page=19610&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big>
<table>
<tr align="left" valign="top">
<td>


{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="F46aa19a1ee469" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
18..345
|
[http://pfam.janelia.org/family/PF07690 PF07690 Major Facilitator Superfamily]
|

|
PMID:19920124

|- class="tableEdit_footer"
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|}


</td>
<td>


<motif_map/>
{{TMHMM Picture|setA}}
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="U46a72f614ccd9" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=setA
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P31675 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P31675 PSI-PRED (P31675)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P31675 Genomes TO Protein (P31675)] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.U46a72f614ccd9&page=19610&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="X46aa19a28cd06" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.X46aa19a28cd06&page=19610&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Z46aa19a2d5943" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/49175994 GI:49175994]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/YP_025293.1 GeneID:944793]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0000257
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P31675 UniProtKB/Swiss-Prot:P31675]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG11754
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG11754
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=944793 GeneID:944793]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120001692
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB1704
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

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|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="B46a72f645e9c6" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.B46a72f645e9c6&page=19610&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

setA:Gene Product(s)

2020-07-22T22:54:27Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|setA}}{{Tab|Gene|setA}}{{Tab On|Gene Product(s)|setA}}{{Tab|Expression|setA}}{{Tab|Evolution|setA}}{{Tab|On One Page|setA}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="I46aa19999383d" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
SetA
|-
!align=left {{table heading style}} |Synonyms
||
''broad specificity sugar efflux system<ref name='LIB:Riley_2006'/>, B0070<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SetA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YabM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0072, JW0069, yabM, b0070''
|-
!align=left {{table heading style}} |Product description
||
YabM MFS transporter<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

Broad specificity sugar efflux transporter<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="X46aa199a8b148" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0997
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-1003
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005351
|
carbohydrate:proton symporter activity
|
*GOA:interpro
*GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|

|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016020
|
membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0472
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004750
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0812
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0015767
|
lactose transport
|
PMID:10438463
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GO_REF:0000023
|
IEA: Inferred from Electronic Annotation
|
SP_SL:SL-9909
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0015758
|
glucose transport
|
PMID:10438463
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0016020
|
membrane
|
PMID:10438463
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.X46aa199a8b148&page=19610&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Z46aa199fd1994" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.Z46aa199fd1994&page=19610&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="V46a72f5fcbb90" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-
|
plasma membrane
|
C-terminus localized in the cytoplasm with 12 predicted transmembrane domains
|
Daley et al. (2005) <ref name=PMID:15919996/>
|

|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.V46a72f5fcbb90&page=19610&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="S46aa19a1960ec" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=B0070-MONOMER at EcoCyc]
<pre>MIWIMTMARR MNGVYAAFML VAFMMGVAGA LQAPTLSLFL SREVGAQPFW IGLFYTVNAI
AGIGVSLWLA KRSDSQGDRR KLIIFCCLMA IGNALLFAFN RHYLTLITCG VLLASLANTA
MPQLFALARE YADNSAREVV MFSSVMRAQL SLAWVIGPPL AFMLALNYGF TVMFSIAAGI
FTLSLVLIAF MLPSVARVEL PSENALSMQG GWQDSNVRML FVASTLMWTC NTMYIIDMPL
WISSELGLPD KLAGFLMGTA AGLEIPAMIL AGYYVKRYGK RRMMVIAVAA GVLFYTGLIF
FNSRMALMTL QLFNAVFIGI VAGIGMLWFQ DLMPGRAGAA TTLFTNSIST GVILAGVIQG
AIAQSWGHFA VYWVIAVISV VALFLTAKVK DV</pre>
|-
!align=left {{table heading style}} |Length
||
392
|-
!align=left {{table heading style}} |Mol. Wt
||
42.714 kDa
|-
!align=left {{table heading style}} |pI
||
9.9 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
71,390 - 71,890 (calc based on 11 Y, 10 W, and 4 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.S46aa19a1960ec&page=19610&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big>
<table>
<tr align="left" valign="top">
<td>


{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="F46aa19a1ee469" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
18..345
|
[http://pfam.janelia.org/family/PF07690 PF07690 Major Facilitator Superfamily]
|

|
PMID:19920124

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.F46aa19a1ee469&page=19610&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}


</td>
<td>


<motif_map/>
{{TMHMM Picture|setA}}
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="U46a72f614ccd9" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=setA
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P31675 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P31675 PSI-PRED (P31675)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P31675 Genomes TO Protein (P31675)] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.U46a72f614ccd9&page=19610&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="X46aa19a28cd06" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.X46aa19a28cd06&page=19610&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Z46aa19a2d5943" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/49175994 GI:49175994]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/YP_025293.1 GeneID:944793]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0000257
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P31675 UniProtKB/Swiss-Prot:P31675]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG11754
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG11754
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=944793 GeneID:944793]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120001692
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB1704
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.Z46aa19a2d5943&page=19610&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="B46a72f645e9c6" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19610.B46a72f645e9c6&page=19610&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

dcuS:Gene Product(s)

2020-07-22T22:51:34Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|dcuS}}{{Tab|Gene|dcuS}}{{Tab On|Gene Product(s)|dcuS}}{{Tab|Expression|dcuS}}{{Tab|Evolution|dcuS}}{{Tab|On One Page|dcuS}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="A46ab1eb587604" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
DcuS
|-
!align=left {{table heading style}} |Synonyms
||
''B4125<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YjdH<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ECK4118, JW4086, yjdH, b4125''
|-
!align=left {{table heading style}} |Product description
||
sensory histidine kinase in two-component regulatory system with DcuR, regulator of anaerobic fumarate respiration<ref name='LIB:Riley_2006'/>

C4-dicarboxylate regulation of anaerobic fumurate respiratory system; two-component system sensory histidine kinase<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.28943.A46ab1eb587604&page=28943&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="F46ab1eb6b2cb0" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0000155
|
phosphorelay sensor kinase activity
|
PMID:12167640
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0006355
|
regulation of transcription, DNA-dependent
|
PMID:14996819
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
PMID:12907689
|
ISS: Inferred from Sequence or Structural Similarity
|
EcoliWiki:citA

|
C
|
NMR was used to determine the protein structure. It showed structural similarity to the CitA family of sensors.
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
PMID:11803016
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete
|-
|

|
GO:0000160
|
two-component signal transduction system (phosphorelay)
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR016120
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0000160
|
two-component signal transduction system (phosphorelay)
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0902
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0000166
|
nucleotide binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0547
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0004673
|
protein histidine kinase activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR005467
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0004673
|
protein histidine kinase activity
|
GOA:spec GO_REF:0000003
|
IEA: Inferred from Electronic Annotation
|
EC:2.7.13.3
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0997
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-1003
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006468
|
protein amino acid phosphorylation
|
PMID:12167640
|
IDA: Inferred from Direct Assay
|

|
P
|
Figure 1
|
complete
|-
|

|
GO:0006355
|
regulation of transcription, DNA-dependent
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR013767
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0004673
|
protein histidine kinase activity
|
PMID:12167640
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0007165
|
signal transduction
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000014
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0000160
|
two-component signal transduction system (phosphorelay)
|
PMID:12167640
|
IDA: Inferred from Direct Assay
|

|
P
|
with DcuR
|
complete
|-
|

|
GO:0007165
|
signal transduction
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR005467
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016020
|
membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0472
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0812
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GO_REF:0000023
|
IEA: Inferred from Electronic Annotation
|
SP_SL:SL-9909
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016301
|
kinase activity
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0418
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016310
|
phosphorylation
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004358
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.28943.F46ab1eb6b2cb0&page=28943&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>


{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Z46ab1ec31d507" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
sdhA 
|

|
PMID:16606699
|
Experiment(s):EBI-1147500 

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|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="D46ab1ec3e4d6a" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-
|
plasma membrane
|
C-terminus localized in the cytoplasm with 2 predicted transmembrane domains
|
Daley et al. (2005) <ref name=PMID:15919996/>
|

|

|-
|
plasma membrane
|

|

|

|

|- class="tableEdit_footer"
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|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="G46ab1ec5a8229" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=PHOSPHO-DCUS-MONOMER at EcoCyc]
<pre>MRHSLPYRML RKRPMKLSTT VILMVSAVLF SVLLVVHLIY FSQISDMTRD GLANKALAVA
RTLADSPEIR QGLQKKPQES GIQAIAEAVR KRNDLLFIVV TDMQSLRYSH PEAQRIGQPF
KGDDILKALN GEENVAINRG FLAQALRVFT PIYDENHKQI GVVAIGLELS RVTQQINDSR
WSIIWSVLFG MLVGLIGTCI LVKVLKKILF GLEPYEISTL FEQRQAMLQS IKEGVVAVDD
RGEVTLINDA AQELLNYRKS QDDEKLSTLS HSWSQVVDVS EVLRDGTPRR DEEITIKDRL
LLINTVPVRS NGVIIGAIST FRDKTEVRKL MQRLDGLVNY ADALRERSHE FMNKLHVILG
LLHLKSYKQL EDYILKTANN YQEEIGSLLG KIKSPVIAGF LISKINRATD LGHTLILNSE
SQLPDSGSED QVATLITTLG NLIENALEAL GPEPGGEISV TLHYRHGWLH CEVNDDGPGI
APDKIDHIFD KGVSTKGSER GVGLALVKQQ VENLGGSIAV ESEPGIFTQF FVQIPWDGER SNR</pre>
|-
!align=left {{table heading style}} |Length
||
543
|-
!align=left {{table heading style}} |Mol. Wt
||
60.552 kDa
|-
!align=left {{table heading style}} |pI
||
6.7 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
43,890 - 44,140 (calc based on 11 Y, 5 W, and 2 C residues)

|- class="tableEdit_footer"
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|}


<big>'''Domains/Motifs/Modification Sites'''</big>
<table>
<tr align="left" valign="top">
<td>


{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Z46ab1ec62d962" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
430..537
|
[http://pfam.janelia.org/family/PF02518 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase]
|

|
PMID:19920124
|-
|
Domain
|
222..324
|
[http://pfam.janelia.org/family/PF00989 PF00989 PAS fold]
|

|
PMID:19920124

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</td>
<td>


<motif_map/>
{{TMHMM Picture|dcuS}}
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="L46ab1ec691fda" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=dcuS
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P0AEC8 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P0AEC8 PSI-PRED (P0AEC8)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P0AEC8 Genomes TO Protein (P0AEC8)] (GTOP)

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|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="W46ab1ec7048ec" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.28943.W46ab1ec7048ec&page=28943&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Z46ab1ec76b225" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16131951 GI:16131951]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_418549.1 GeneID:948639]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0013509
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P0AEC8 UniProtKB/Swiss-Prot:P0AEC8]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:G7827
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG12465
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=948639 GeneID:948639]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120004324
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB2358
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Y46ab1ed882104" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
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|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:Proteins]]

Category:GO:0006355 ! regulation of transcription, DNA-templated

2020-07-22T22:50:45Z

Siegele: Created page with "."

dcuS:Gene Product(s)

2020-07-22T22:49:18Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|dcuS}}{{Tab|Gene|dcuS}}{{Tab On|Gene Product(s)|dcuS}}{{Tab|Expression|dcuS}}{{Tab|Evolution|dcuS}}{{Tab|On One Page|dcuS}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="A46ab1eb587604" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
DcuS
|-
!align=left {{table heading style}} |Synonyms
||
''B4125<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YjdH<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ECK4118, JW4086, yjdH, b4125''
|-
!align=left {{table heading style}} |Product description
||
sensory histidine kinase in two-component regulatory system with DcuR, regulator of anaerobic fumarate respiration<ref name='LIB:Riley_2006'/>

C4-dicarboxylate regulation of anaerobic fumurate respiratory system; two-component system sensory histidine kinase<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="F46ab1eb6b2cb0" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0000155
|
phosphorelay sensor kinase activity
|
PMID:12167640
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0006355
|
regulation of transcription, DNA-dependent
|
PMID:14996819
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
PMID:12907689
|
ISS: Inferred from Sequence or Structural Similarity
|
EcoliWiki:citA

|
C
|
NMR was used to determine the protein structure. It showed structural similarity to the CitA family of sensors.
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
PMID:11803016
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete
|-
|

|
GO:0000160
|
two-component signal transduction system (phosphorelay)
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR016120
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0000160
|
two-component signal transduction system (phosphorelay)
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0902
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0000166
|
nucleotide binding
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0547
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0004673
|
protein histidine kinase activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR005467
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0004673
|
protein histidine kinase activity
|
GOA:spec GO_REF:0000003
|
IEA: Inferred from Electronic Annotation
|
EC:2.7.13.3
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0004871
|
signal transducer activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000014
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0997
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-1003
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006468
|
protein amino acid phosphorylation
|
PMID:12167640
|
IDA: Inferred from Direct Assay
|

|
P
|
Figure 1
|
complete
|-
|

|
GO:0006355
|
regulation of transcription, DNA-dependent
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR013767
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0004673
|
protein histidine kinase activity
|
PMID:12167640
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0007165
|
signal transduction
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000014
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0000160
|
two-component signal transduction system (phosphorelay)
|
PMID:12167640
|
IDA: Inferred from Direct Assay
|

|
P
|
with DcuR
|
complete
|-
|

|
GO:0007165
|
signal transduction
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR005467
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016020
|
membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0472
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0812
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GO_REF:0000023
|
IEA: Inferred from Electronic Annotation
|
SP_SL:SL-9909
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016301
|
kinase activity
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0418
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016310
|
phosphorylation
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004358
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.28943.F46ab1eb6b2cb0&page=28943&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>


{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Z46ab1ec31d507" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
sdhA 
|

|
PMID:16606699
|
Experiment(s):EBI-1147500 

|- class="tableEdit_footer"
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|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="D46ab1ec3e4d6a" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-
|
plasma membrane
|
C-terminus localized in the cytoplasm with 2 predicted transmembrane domains
|
Daley et al. (2005) <ref name=PMID:15919996/>
|

|

|-
|
plasma membrane
|

|

|

|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.28943.D46ab1ec3e4d6a&page=28943&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="G46ab1ec5a8229" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=PHOSPHO-DCUS-MONOMER at EcoCyc]
<pre>MRHSLPYRML RKRPMKLSTT VILMVSAVLF SVLLVVHLIY FSQISDMTRD GLANKALAVA
RTLADSPEIR QGLQKKPQES GIQAIAEAVR KRNDLLFIVV TDMQSLRYSH PEAQRIGQPF
KGDDILKALN GEENVAINRG FLAQALRVFT PIYDENHKQI GVVAIGLELS RVTQQINDSR
WSIIWSVLFG MLVGLIGTCI LVKVLKKILF GLEPYEISTL FEQRQAMLQS IKEGVVAVDD
RGEVTLINDA AQELLNYRKS QDDEKLSTLS HSWSQVVDVS EVLRDGTPRR DEEITIKDRL
LLINTVPVRS NGVIIGAIST FRDKTEVRKL MQRLDGLVNY ADALRERSHE FMNKLHVILG
LLHLKSYKQL EDYILKTANN YQEEIGSLLG KIKSPVIAGF LISKINRATD LGHTLILNSE
SQLPDSGSED QVATLITTLG NLIENALEAL GPEPGGEISV TLHYRHGWLH CEVNDDGPGI
APDKIDHIFD KGVSTKGSER GVGLALVKQQ VENLGGSIAV ESEPGIFTQF FVQIPWDGER SNR</pre>
|-
!align=left {{table heading style}} |Length
||
543
|-
!align=left {{table heading style}} |Mol. Wt
||
60.552 kDa
|-
!align=left {{table heading style}} |pI
||
6.7 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
43,890 - 44,140 (calc based on 11 Y, 5 W, and 2 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.28943.G46ab1ec5a8229&page=28943&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big>
<table>
<tr align="left" valign="top">
<td>


{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Z46ab1ec62d962" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
430..537
|
[http://pfam.janelia.org/family/PF02518 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase]
|

|
PMID:19920124
|-
|
Domain
|
222..324
|
[http://pfam.janelia.org/family/PF00989 PF00989 PAS fold]
|

|
PMID:19920124

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.28943.Z46ab1ec62d962&page=28943&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}


</td>
<td>


<motif_map/>
{{TMHMM Picture|dcuS}}
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="L46ab1ec691fda" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=dcuS
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P0AEC8 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P0AEC8 PSI-PRED (P0AEC8)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P0AEC8 Genomes TO Protein (P0AEC8)] (GTOP)

|- class="tableEdit_footer"
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|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="W46ab1ec7048ec" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.28943.W46ab1ec7048ec&page=28943&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Z46ab1ec76b225" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16131951 GI:16131951]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_418549.1 GeneID:948639]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0013509
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P0AEC8 UniProtKB/Swiss-Prot:P0AEC8]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:G7827
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG12465
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=948639 GeneID:948639]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120004324
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB2358
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

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|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Y46ab1ed882104" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.28943.Y46ab1ed882104&page=28943&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:Proteins]]

ggt:Gene Product(s)

2020-07-22T22:35:46Z

Siegele: /* Function */ GO Annotation table was updated, so deleted reminder.

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|ggt}}{{Tab|Gene|ggt}}{{Tab On|Gene Product(s)|ggt}}{{Tab|Expression|ggt}}{{Tab|Evolution|ggt}}{{Tab|On One Page|ggt}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="R46aaea88b9777" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
Ggt
|-
!align=left {{table heading style}} |Synonyms
||
''gamma-glutamyltranspeptidase<ref name='LIB:Riley_2006'/>, B3447<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Ggt<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3431, JW3412, b3447''
|-
!align=left {{table heading style}} |Product description
||
γ-glutamyltranspeptidase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

gamma-Glutamyltranspeptidase, glutathione metabolism; Ntn hydrolase; autocatalytic processing into two subunits; periplasmic<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.2 2.3.2.2]<ref name='LIB:Riley_2006'/>

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27398.R46aaea88b9777&page=27398&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="E46aaea89d08bd" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0030288
|
outer membrane-bounded periplasmic space
|

|

|

|
C
|
Seeded from Riley et al 2006 <ref name='LIB:Riley_2006'/>.
|
Missing: evidence, reference
|-
|

|
GO:0006750
|
glutathione biosynthetic process
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0317
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008415
|
acyltransferase activity
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0012
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016740
|
transferase activity
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0808
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0042597
|
periplasmic space
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0574
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0042597
|
periplasmic space
|
GO_REF:0000023
|
IEA: Inferred from Electronic Annotation
|
SP_SL:SL-0200
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0042597
|
periplasmic space
|
PMID:2877975
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete
|-
|

|
GO:0036374
|
glutathione hydrolase activity
|
PMID:2877974
|
IDA: Inferred from Direct Assay
|

|
F
|
Table 2
|
complete

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27398.E46aaea89d08bd&page=27398&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="T46aaea94a52c9" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27398.T46aaea94a52c9&page=27398&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="D46aaea957d92d" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-
|
Periplasm
|

|
PMID:2570061
|
[http://www.york.ac.uk/res/thomas/Echolocation.cfm?EB_SubLocID=EB0369 EchoLocation:ggt]
|

|-
|
periplasm
|

|

|
From EcoCyc<ref name='LIB:EcoCyc11.1'/>
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27398.D46aaea957d92d&page=27398&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="Q46aaea974a1aa" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=EG10374-MONOMER at EcoCyc]
<pre>MIKPTFLRRV AIAALLSGSC FSAAAAPPAP PVSYGVEEDV FHPVRAKQGM VASVDATATQ
VGVDILKEGG NAVDAAVAVG YALAVTHPQA GNLGGGGFML IRSKNGNTTA IDFREMAPAK
ATRDMFLDDQ GNPDSKKSLT SHLASGTPGT VAGFSLALDK YGTMPLNKVV QPAFKLARDG
FIVNDALADD LKTYGSEVLP NHENSKAIFW KEGEPLKKGD TLVQANLAKS LEMIAENGPD
EFYKGTIAEQ IAQEMQKNGG LITKEDLAAY KAVERTPISG DYRGYQVYSM PPPSSGGIHI
VQILNILENF DMKKYGFGSA DAMQIMAEAE KYAYADRSEY LGDPDFVKVP WQALTNKAYA
KSIADQIDIN KAKPSSEIRP GKLAPYESNQ TTHYSVVDKD GNAVAVTYTL NTTFGTGIVA
GESGILLNNQ MDDFSAKPGV PNVYGLVGGD ANAVGPNKRP LSSMSPTIVV KDGKTWLVTG
SPGGSRIITT VLQMVVNSID YGLNVAEATN APRFHHQWLP DELRVEKGFS PDTLKLLEAK
GQKVALKEAM GSTQSIMVGP DGELYGASDP RSVDDLTAGY</pre>
|-
!align=left {{table heading style}} |Length
||
580
|-
!align=left {{table heading style}} |Mol. Wt
||
61.768 kDa
|-
!align=left {{table heading style}} |pI
||
5.3 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
53,290 - 53,415 (calc based on 21 Y, 4 W, and 1 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27398.Q46aaea974a1aa&page=27398&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Q46aaea97bfd9a" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
motif
|
1-25
|
[[uniprotmanual:signal|UniProt Manual:Signal Peptides]]
|
[http://www.uniprot.org/uniprot/P18956#section_features UniProt:P18956]
|

|-
|
Domain
|
63..574
|
[http://pfam.janelia.org/family/PF01019 PF01019 Gamma-glutamyltranspeptidase]
|

|
PMID:19920124

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27398.Q46aaea97bfd9a&page=27398&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="S46aaea982d8ad" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=ggt
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P18956 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P18956 PSI-PRED (P18956)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P18956 Genomes TO Protein (P18956)] (GTOP)

|- class="tableEdit_footer"
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|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="U46aaea9b38109" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27398.U46aaea9b38109&page=27398&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="A46aaea9b9a910" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16131319 GI:16131319]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_417904.1 GeneID:947947]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0011257
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P18956 UniProtKB/Swiss-Prot:P18956]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG10374
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG10374
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=947947 GeneID:947947]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120000367
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB0369
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

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|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="P46a87a26c48d9" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

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|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

ggt:Gene Product(s)

2020-07-22T22:34:29Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|ggt}}{{Tab|Gene|ggt}}{{Tab On|Gene Product(s)|ggt}}{{Tab|Expression|ggt}}{{Tab|Evolution|ggt}}{{Tab|On One Page|ggt}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="R46aaea88b9777" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
Ggt
|-
!align=left {{table heading style}} |Synonyms
||
''gamma-glutamyltranspeptidase<ref name='LIB:Riley_2006'/>, B3447<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Ggt<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3431, JW3412, b3447''
|-
!align=left {{table heading style}} |Product description
||
γ-glutamyltranspeptidase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

gamma-Glutamyltranspeptidase, glutathione metabolism; Ntn hydrolase; autocatalytic processing into two subunits; periplasmic<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.2 2.3.2.2]<ref name='LIB:Riley_2006'/>

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27398.R46aaea88b9777&page=27398&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="E46aaea89d08bd" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0030288
|
outer membrane-bounded periplasmic space
|

|

|

|
C
|
Seeded from Riley et al 2006 <ref name='LIB:Riley_2006'/>.
|
Missing: evidence, reference
|-
|

|
GO:0006750
|
glutathione biosynthetic process
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0317
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008415
|
acyltransferase activity
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0012
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016740
|
transferase activity
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0808
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0042597
|
periplasmic space
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0574
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0042597
|
periplasmic space
|
GO_REF:0000023
|
IEA: Inferred from Electronic Annotation
|
SP_SL:SL-0200
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0042597
|
periplasmic space
|
PMID:2877975
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete
|-
|

|
GO:0036374
|
glutathione hydrolase activity
|
PMID:2877974
|
IDA: Inferred from Direct Assay
|

|
F
|
Table 2
|
complete

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27398.E46aaea89d08bd&page=27398&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


GO:0003840 ! gamma-glutamyltransferase activity was made obsolete because it is not a physiological function. GO:0003840 in the table above should be replaced with GO:0036374 ! glutathione hydrolase activity
(IDA PMID:2877974-Table 2).

<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="T46aaea94a52c9" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27398.T46aaea94a52c9&page=27398&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="D46aaea957d92d" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-
|
Periplasm
|

|
PMID:2570061
|
[http://www.york.ac.uk/res/thomas/Echolocation.cfm?EB_SubLocID=EB0369 EchoLocation:ggt]
|

|-
|
periplasm
|

|

|
From EcoCyc<ref name='LIB:EcoCyc11.1'/>
|

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|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27398.D46aaea957d92d&page=27398&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
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<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="Q46aaea974a1aa" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=EG10374-MONOMER at EcoCyc]
<pre>MIKPTFLRRV AIAALLSGSC FSAAAAPPAP PVSYGVEEDV FHPVRAKQGM VASVDATATQ
VGVDILKEGG NAVDAAVAVG YALAVTHPQA GNLGGGGFML IRSKNGNTTA IDFREMAPAK
ATRDMFLDDQ GNPDSKKSLT SHLASGTPGT VAGFSLALDK YGTMPLNKVV QPAFKLARDG
FIVNDALADD LKTYGSEVLP NHENSKAIFW KEGEPLKKGD TLVQANLAKS LEMIAENGPD
EFYKGTIAEQ IAQEMQKNGG LITKEDLAAY KAVERTPISG DYRGYQVYSM PPPSSGGIHI
VQILNILENF DMKKYGFGSA DAMQIMAEAE KYAYADRSEY LGDPDFVKVP WQALTNKAYA
KSIADQIDIN KAKPSSEIRP GKLAPYESNQ TTHYSVVDKD GNAVAVTYTL NTTFGTGIVA
GESGILLNNQ MDDFSAKPGV PNVYGLVGGD ANAVGPNKRP LSSMSPTIVV KDGKTWLVTG
SPGGSRIITT VLQMVVNSID YGLNVAEATN APRFHHQWLP DELRVEKGFS PDTLKLLEAK
GQKVALKEAM GSTQSIMVGP DGELYGASDP RSVDDLTAGY</pre>
|-
!align=left {{table heading style}} |Length
||
580
|-
!align=left {{table heading style}} |Mol. Wt
||
61.768 kDa
|-
!align=left {{table heading style}} |pI
||
5.3 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
53,290 - 53,415 (calc based on 21 Y, 4 W, and 1 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27398.Q46aaea974a1aa&page=27398&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Q46aaea97bfd9a" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
motif
|
1-25
|
[[uniprotmanual:signal|UniProt Manual:Signal Peptides]]
|
[http://www.uniprot.org/uniprot/P18956#section_features UniProt:P18956]
|

|-
|
Domain
|
63..574
|
[http://pfam.janelia.org/family/PF01019 PF01019 Gamma-glutamyltranspeptidase]
|

|
PMID:19920124

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|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="S46aaea982d8ad" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=ggt
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P18956 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P18956 PSI-PRED (P18956)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P18956 Genomes TO Protein (P18956)] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27398.S46aaea982d8ad&page=27398&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="U46aaea9b38109" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27398.U46aaea9b38109&page=27398&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="A46aaea9b9a910" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16131319 GI:16131319]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_417904.1 GeneID:947947]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0011257
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P18956 UniProtKB/Swiss-Prot:P18956]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG10374
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG10374
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=947947 GeneID:947947]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120000367
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB0369
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27398.A46aaea9b9a910&page=27398&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="P46a87a26c48d9" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27398.P46a87a26c48d9&page=27398&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

Category:GO:0036374 ! glutathione hydrolase activity

2020-07-22T04:08:37Z

Siegele: Created blank page

ggt:Gene Product(s)

2020-07-22T04:07:48Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|ggt}}{{Tab|Gene|ggt}}{{Tab On|Gene Product(s)|ggt}}{{Tab|Expression|ggt}}{{Tab|Evolution|ggt}}{{Tab|On One Page|ggt}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="R46aaea88b9777" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
Ggt
|-
!align=left {{table heading style}} |Synonyms
||
''gamma-glutamyltranspeptidase<ref name='LIB:Riley_2006'/>, B3447<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Ggt<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3431, JW3412, b3447''
|-
!align=left {{table heading style}} |Product description
||
γ-glutamyltranspeptidase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

gamma-Glutamyltranspeptidase, glutathione metabolism; Ntn hydrolase; autocatalytic processing into two subunits; periplasmic<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.2 2.3.2.2]<ref name='LIB:Riley_2006'/>

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27398.R46aaea88b9777&page=27398&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="E46aaea89d08bd" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0030288
|
outer membrane-bounded periplasmic space
|

|

|

|
C
|
Seeded from Riley et al 2006 <ref name='LIB:Riley_2006'/>.
|
Missing: evidence, reference
|-
|

|
GO:0006750
|
glutathione biosynthetic process
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0317
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008415
|
acyltransferase activity
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0012
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0016740
|
transferase activity
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0808
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0042597
|
periplasmic space
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0574
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0042597
|
periplasmic space
|
GO_REF:0000023
|
IEA: Inferred from Electronic Annotation
|
SP_SL:SL-0200
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0042597
|
periplasmic space
|
PMID:2877975
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete
|-
|

|
GO:0036374
|
glutathione hydrolase activity
|
PMID:2877974
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete

|- class="tableEdit_footer"
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|}


GO:0003840 ! gamma-glutamyltransferase activity was made obsolete because it is not a physiological function. GO:0003840 in the table above should be replaced with GO:0036374 ! glutathione hydrolase activity
(IDA PMID:2877974-Table 2).

<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="T46aaea94a52c9" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27398.T46aaea94a52c9&page=27398&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="D46aaea957d92d" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-
|
Periplasm
|

|
PMID:2570061
|
[http://www.york.ac.uk/res/thomas/Echolocation.cfm?EB_SubLocID=EB0369 EchoLocation:ggt]
|

|-
|
periplasm
|

|

|
From EcoCyc<ref name='LIB:EcoCyc11.1'/>
|

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|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="Q46aaea974a1aa" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=EG10374-MONOMER at EcoCyc]
<pre>MIKPTFLRRV AIAALLSGSC FSAAAAPPAP PVSYGVEEDV FHPVRAKQGM VASVDATATQ
VGVDILKEGG NAVDAAVAVG YALAVTHPQA GNLGGGGFML IRSKNGNTTA IDFREMAPAK
ATRDMFLDDQ GNPDSKKSLT SHLASGTPGT VAGFSLALDK YGTMPLNKVV QPAFKLARDG
FIVNDALADD LKTYGSEVLP NHENSKAIFW KEGEPLKKGD TLVQANLAKS LEMIAENGPD
EFYKGTIAEQ IAQEMQKNGG LITKEDLAAY KAVERTPISG DYRGYQVYSM PPPSSGGIHI
VQILNILENF DMKKYGFGSA DAMQIMAEAE KYAYADRSEY LGDPDFVKVP WQALTNKAYA
KSIADQIDIN KAKPSSEIRP GKLAPYESNQ TTHYSVVDKD GNAVAVTYTL NTTFGTGIVA
GESGILLNNQ MDDFSAKPGV PNVYGLVGGD ANAVGPNKRP LSSMSPTIVV KDGKTWLVTG
SPGGSRIITT VLQMVVNSID YGLNVAEATN APRFHHQWLP DELRVEKGFS PDTLKLLEAK
GQKVALKEAM GSTQSIMVGP DGELYGASDP RSVDDLTAGY</pre>
|-
!align=left {{table heading style}} |Length
||
580
|-
!align=left {{table heading style}} |Mol. Wt
||
61.768 kDa
|-
!align=left {{table heading style}} |pI
||
5.3 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
53,290 - 53,415 (calc based on 21 Y, 4 W, and 1 C residues)

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|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Q46aaea97bfd9a" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
motif
|
1-25
|
[[uniprotmanual:signal|UniProt Manual:Signal Peptides]]
|
[http://www.uniprot.org/uniprot/P18956#section_features UniProt:P18956]
|

|-
|
Domain
|
63..574
|
[http://pfam.janelia.org/family/PF01019 PF01019 Gamma-glutamyltranspeptidase]
|

|
PMID:19920124

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|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="S46aaea982d8ad" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=ggt
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P18956 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P18956 PSI-PRED (P18956)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P18956 Genomes TO Protein (P18956)] (GTOP)

|- class="tableEdit_footer"
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|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="U46aaea9b38109" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="A46aaea9b9a910" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16131319 GI:16131319]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_417904.1 GeneID:947947]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0011257
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P18956 UniProtKB/Swiss-Prot:P18956]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG10374
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG10374
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=947947 GeneID:947947]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120000367
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB0369
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

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|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="P46a87a26c48d9" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

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|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

ubiG:Gene Product(s)

2020-01-08T02:03:45Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|ubiG}}{{Tab|Gene|ubiG}}{{Tab On|Gene Product(s)|ubiG}}{{Tab|Expression|ubiG}}{{Tab|Evolution|ubiG}}{{Tab|On One Page|ubiG}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="S46aa9a6ad2314" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
UbiG
|-
!align=left {{table heading style}} |Synonyms
||
''bifunctional 3-demethylubiquinone-9 3-methyltransferase and 2-octaprenyl-6-hydroxy phenol methylase<ref name='LIB:Riley_2006'/>, B2232<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PufX<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YfaB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, UbiG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK2224, JW2226, pufX, yfaB, b2232''
|-
!align=left {{table heading style}} |Product description
||
UbiG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;

Component of [[:Category:Complex:3-demethylubiquinone 3-methyltransferase|3-demethylubiquinone 3-methyltransferase]]<ref name='LIB:EcoCyc10.6'/>; [[:Category:Complex:3-demethylubiquinone 3-methyltransferase|bifunctional 3-demethylubiquinone-8 3-O-methyltransferase and 2-octaprenyl-6-hydroxyphenol methylase]]<ref name='LIB:EcoCyc11.1'/>

SAM:OMHMB methyltransferase; Reactions: 2-octaprenyl-6-hydroxylphenol to 2-octaprenyl-6-methoxyphenol; 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone to ubiquinone 8<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.64 2.1.1.64]<ref name='LIB:Riley_2006'/>

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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Y46aa9a6c50b79" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0005737
|
cytoplasm
|

|

|

|
C
|
Seeded from Riley et al 2006 <ref name='LIB:Riley_2006'/>.
|
Missing: evidence, reference
|-
|

|
GO:0008425
|
2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR010233
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008689
|
3-demethylubiquinone-9 3-O-methyltransferase activity
|
GOA:hamap GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_00472
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008689
|
3-demethylubiquinone-9 3-O-methyltransferase activity
|
GOA:spec GO_REF:0000003
|
IEA: Inferred from Electronic Annotation
|
EC:2.1.1.64
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0099119
|
3-demethylubiquinone-8 3-O-methyltransferase activity
|
PMID:10419476
|
IDA: Inferred from Direct Assay
|

|
F
|
Imported from EcoCyc (v 23.5)
|
complete
|-
|

|
GO:0006744
|
ubiquinone biosynthetic process
|
PMID:8703953
|
IGI: Inferred from Genetic Interaction
|

|
P
|
imported from EcoCyc (v 23.5)
complementation of coq3 mutant of Saccharomyces cerevisiae
|
complete

|- class="tableEdit_footer"
|<div class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.24640.Y46aa9a6c50b79&page=24640&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</div> || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="E46aa9a8b0503f" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
Subunits of [[:Category:Complex:3-demethylubiquinone 3-methyltransferase|3-demethylubiquinone 3-methyltransferase]]
|
could be indirect
|

|

|-
|
Protein
|
rpsA 
|

|
PMID:16606699
|
Experiment(s):EBI-1142262 
|-
|
Protein
|
groL 
|

|
PMID:16606699
|
Experiment(s):EBI-1142262 
|-
|
Protein
|
phrB 
|

|
PMID:16606699
|
Experiment(s):EBI-1142262 
|-
|
Protein
|
dnaK 
|

|
PMID:16606699
|
Experiment(s):EBI-1142262 
|-
|
Protein
|
hemG 
|

|
PMID:16606699
|
Experiment(s):EBI-1142262 
|-
|
Protein
|
rplS 
|

|
PMID:16606699
|
Experiment(s):EBI-1142262 
|-
|
Protein
|
rpsM 
|

|
PMID:16606699
|
Experiment(s):EBI-1142262 
|-
|
Protein
|
glpD 
|

|
PMID:16606699
|
Experiment(s):EBI-1142262 
|-
|
Protein
|
hycF 
|

|
PMID:16606699
|
Experiment(s):EBI-1142262 
|-
|
Protein
|
rplV 
|

|
PMID:15690043
|
Experiment(s):EBI-890550 

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|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="A46aa9a8c3769d" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-
|
plasma membrane
|

|

|
From EcoCyc<ref name='LIB:EcoCyc11.1'/>
|

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|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="X46aa9a8dc71f6" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=DHHB-METHYLTRANSFER-MONOMER at EcoCyc]
<pre>MNAEKSPVNH NVDHEEIAKF EAVASRWWDL EGEFKPLHRI NPLRLGYIAE RAGGLFGKKV
LDVGCGGGIL AESMAREGAT VTGLDMGFEP LQVAKLHALE SGIQVDYVQE TVEEHAAKHA
GQYDVVTCME MLEHVPDPQS VVRACAQLVK PGGDVFFSTL NRNGKSWLMA VVGAEYILRM
VPKGTHDVKK FIKPAELLGW VDQTSLKERH ITGLHYNPIT NTFKLGPGVD VNYMLHTQNK</pre>
|-
!align=left {{table heading style}} |Length
||
240
|-
!align=left {{table heading style}} |Mol. Wt
||
26.554 kDa
|-
!align=left {{table heading style}} |pI
||
6.6 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
30,940 - 31,315 (calc based on 6 Y, 4 W, and 3 C residues)

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|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="R46aa9a8e40700" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
61..157
|
[http://pfam.janelia.org/family/PF08241 PF08241 Methyltransferase domain]
|

|
PMID:19920124

|- class="tableEdit_footer"
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|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="W46a82f3d7672c" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=ubiG
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P17993 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P17993 PSI-PRED (P17993)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P17993 Genomes TO Protein (P17993)] (GTOP)

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|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="W46aa9a8f06c02" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
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<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="F46aa9a8f63a5d" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16130167 GI:16130167]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_416735.1 GeneID:946607]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0007374
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P17993 UniProtKB/Swiss-Prot:P17993]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG11143
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG11143
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=946607 GeneID:946607]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120001127
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB1133
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

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<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


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!|Name!!URL!!Comments

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<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

ubiG:Gene Product(s)

2020-01-08T01:56:21Z

Siegele: Table edited by $2 via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|ubiG}}{{Tab|Gene|ubiG}}{{Tab On|Gene Product(s)|ubiG}}{{Tab|Expression|ubiG}}{{Tab|Evolution|ubiG}}{{Tab|On One Page|ubiG}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="S46aa9a6ad2314" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
UbiG
|-
!align=left {{table heading style}} |Synonyms
||
''bifunctional 3-demethylubiquinone-9 3-methyltransferase and 2-octaprenyl-6-hydroxy phenol methylase<ref name='LIB:Riley_2006'/>, B2232<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PufX<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YfaB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, UbiG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK2224, JW2226, pufX, yfaB, b2232''
|-
!align=left {{table heading style}} |Product description
||
UbiG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;

Component of [[:Category:Complex:3-demethylubiquinone 3-methyltransferase|3-demethylubiquinone 3-methyltransferase]]<ref name='LIB:EcoCyc10.6'/>; [[:Category:Complex:3-demethylubiquinone 3-methyltransferase|bifunctional 3-demethylubiquinone-8 3-O-methyltransferase and 2-octaprenyl-6-hydroxyphenol methylase]]<ref name='LIB:EcoCyc11.1'/>

SAM:OMHMB methyltransferase; Reactions: 2-octaprenyl-6-hydroxylphenol to 2-octaprenyl-6-methoxyphenol; 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone to ubiquinone 8<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.64 2.1.1.64]<ref name='LIB:Riley_2006'/>

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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="Y46aa9a6c50b79" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0005737
|
cytoplasm
|

|

|

|
C
|
Seeded from Riley et al 2006 <ref name='LIB:Riley_2006'/>.
|
Missing: evidence, reference
|-
|

|
GO:0006744
|
ubiquinone biosynthetic process
|
GOA:hamap GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_00472
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006744
|
ubiquinone biosynthetic process
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR010233
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0006744
|
ubiquinone biosynthetic process
|
GOA:spkw SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0831
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008425
|
2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity
|
GOA:interpro GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR010233
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008689
|
3-demethylubiquinone-9 3-O-methyltransferase activity
|
GOA:hamap GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_00472
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0008689
|
3-demethylubiquinone-9 3-O-methyltransferase activity
|
GOA:spec GO_REF:0000003
|
IEA: Inferred from Electronic Annotation
|
EC:2.1.1.64
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|

|
GO:0099119
|
3-demethylubiquinone-8 3-O-methyltransferase activity
|
PMID:10419476
|
IDA: Inferred from Direct Assay
|

|
F
|
Imported from EcoCyc 23.5
|
complete

|- class="tableEdit_footer"
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<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="E46aa9a8b0503f" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
Subunits of [[:Category:Complex:3-demethylubiquinone 3-methyltransferase|3-demethylubiquinone 3-methyltransferase]]
|
could be indirect
|

|

|-
|
Protein
|
rpsA 
|

|
PMID:16606699
|
Experiment(s):EBI-1142262 
|-
|
Protein
|
groL 
|

|
PMID:16606699
|
Experiment(s):EBI-1142262 
|-
|
Protein
|
phrB 
|

|
PMID:16606699
|
Experiment(s):EBI-1142262 
|-
|
Protein
|
dnaK 
|

|
PMID:16606699
|
Experiment(s):EBI-1142262 
|-
|
Protein
|
hemG 
|

|
PMID:16606699
|
Experiment(s):EBI-1142262 
|-
|
Protein
|
rplS 
|

|
PMID:16606699
|
Experiment(s):EBI-1142262 
|-
|
Protein
|
rpsM 
|

|
PMID:16606699
|
Experiment(s):EBI-1142262 
|-
|
Protein
|
glpD 
|

|
PMID:16606699
|
Experiment(s):EBI-1142262 
|-
|
Protein
|
hycF 
|

|
PMID:16606699
|
Experiment(s):EBI-1142262 
|-
|
Protein
|
rplV 
|

|
PMID:15690043
|
Experiment(s):EBI-890550 

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</protect>
===Notes===

==Localization==

{{Product_localization_help}}
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|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-
|
plasma membrane
|

|

|
From EcoCyc<ref name='LIB:EcoCyc11.1'/>
|

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<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="X46aa9a8dc71f6" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Name
||

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=DHHB-METHYLTRANSFER-MONOMER at EcoCyc]
<pre>MNAEKSPVNH NVDHEEIAKF EAVASRWWDL EGEFKPLHRI NPLRLGYIAE RAGGLFGKKV
LDVGCGGGIL AESMAREGAT VTGLDMGFEP LQVAKLHALE SGIQVDYVQE TVEEHAAKHA
GQYDVVTCME MLEHVPDPQS VVRACAQLVK PGGDVFFSTL NRNGKSWLMA VVGAEYILRM
VPKGTHDVKK FIKPAELLGW VDQTSLKERH ITGLHYNPIT NTFKLGPGVD VNYMLHTQNK</pre>
|-
!align=left {{table heading style}} |Length
||
240
|-
!align=left {{table heading style}} |Mol. Wt
||
26.554 kDa
|-
!align=left {{table heading style}} |pI
||
6.6 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
30,940 - 31,315 (calc based on 6 Y, 4 W, and 3 C residues)

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<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="R46aa9a8e40700" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Domain
|
61..157
|
[http://pfam.janelia.org/family/PF08241 PF08241 Methyltransferase domain]
|

|
PMID:19920124

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|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="W46a82f3d7672c" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=ubiG
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P17993 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P17993 PSI-PRED (P17993)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P17993 Genomes TO Protein (P17993)] (GTOP)

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</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="W46aa9a8f06c02" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

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<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="F46aa9a8f63a5d" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16130167 GI:16130167]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_416735.1 GeneID:946607]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0007374
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P17993 UniProtKB/Swiss-Prot:P17993]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:EG11143
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EcoGene]]
|
EcoGene:EG11143
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/gene?term=946607 GeneID:946607]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[RegulonDB]]
|
RegulonDB:ECK120001127
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[[EchoBASE]]
|
EchoBASE:EB1133
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]

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|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="W46a82f40ee33d" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

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<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]

Category:Strain:MC4100

2019-11-23T00:19:22Z

Siegele: Table edited by $2 via TableEdit

{{See|Help:Strains|strains}}
<protect>

{| id="W4e4032086078f" class=" tableEdit Strain_Geneology_Table dataTable"

|-
!align=left {{table_heading_style}} |Name
||
MC4100
|-
!align=left {{table_heading_style}} |Synonyms
||

|-
!align=left {{table_heading_style}} |Genotype
||
F- [araD139]B/r DE(argF-lac)169 Lambda- e14- flhD5301 DE(fruK-yeiR)725(fruA25) relA1 rpsL150(strR) rbsR22 DE(fimB-fimE)632(::IS1) deoC1
|-
!align=left {{table_heading_style}} |Phenotype
||

|-
!align=left {{table_heading_style}} |Plasmids
||

|-
!align=left {{table_heading_style}} |Phage
||

|-
!align=left {{table_heading_style}} |Sources
||
CGSC6152
|-
!align=left {{table_heading_style}} |Construction
||

|-
!align=left {{table_heading_style}} |References
||

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|}
</protect>

== Notes ==
Differences with MG1655 were examined by microarray analysis<ref name='PMID:12618467'/>. A complete genome sequence was determined for an MC4100 derivative, [[:Category:Gene_List:BW2952|BW2952]]<ref name='PMID:19376874'/>

==References==
{{RefHelp}}
<references/>

__NOTOC__
[[Category:Strain:Hfr 3000]]

Category:Strain:BW25113

2019-08-13T04:30:56Z

Siegele: Table edited by $2 via TableEdit

{{See|Help:Strains|strains}}
<protect>

{| id="N5159d535a6d9e" class=" tableEdit Strain_Geneology_Table dataTable"

|-
!align=left {{table_heading_style}} |Name
||
BW25113
|-
!align=left {{table_heading_style}} |Synonyms
||

|-
!align=left {{table_heading_style}} |Genotype
||
F- DE(araD-araB)567 lacZ4787(del)::rrnB-3 LAM- rph-1 DE(rhaD-rhaB)568 hsdR514
|-
!align=left {{table_heading_style}} |Phenotype
||

|-
!align=left {{table_heading_style}} |Plasmids
||

|-
!align=left {{table_heading_style}} |Phage
||

|-
!align=left {{table_heading_style}} |Sources
||
[http://cgsc.biology.yale.edu/Strain.php?ID=64667 Coli Genetics Stock Center]
|-
!align=left {{table_heading_style}} |Construction
||
see description below
|-
!align=left {{table_heading_style}} |References
||
PMID:10829079

PMID:16738554

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== Notes ==
BW25113 was used to make the Keio Collection of single-gene knockouts. <ref name=PMID:16738554/>
<ref name=PMID:10829079/> BW25113 is available from the Coli Genetics Stock Center: [http://cgsc2.biology.yale.edu/Strain.php?ID=64667 CGSC#7636]
The genotype for BW25113 in Datsenko et al. <ref name=PMID:10829079/> said the strain is lacIQ, but it was later shown to be lacI+ Baba et al. (Supplementary Table 1)<ref name=PMID:16738554/>.

According to the CGSC, ''lacZ4787(del)'' has 4 tandem copies of the rrnB transcriptional terminator inserted by gene replacement into the region extending from near the SacII site near the N-terminus of ''lacZ'' through the promoter.

BW25113 is a derivative of ''E. coli'' K-12 strain [http://cgsc2.biology.yale.edu/Strain.php?ID=7024 BD792], which has the genotype F- LAM- rpoS396(Am) rph-1.

The steps in the construction of BW25113 are described below. This information is from Supplementary Table 1 of Baba et al.(<ref name='PMID:16738554'/>). At several steps of the strain construction, mutant alleles were constructed in vitro and recombined into the genome using oriRR6Kgamma plasmids, which cannot replicate in a strain that lacks the R6K ''pir'' gene (<ref name='PMID:8693022'/>). In the absence of selection of the antibiotic resistance marker carried on the plasmid, homologous recombination can occur that will either restore the original genotype or result in allele replacement.



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!|Step!!Strain!!Genotype!!Construction!!Reference
|-
|
ii)
|
BW21597
|
F- LAM- rpoS396(Am) DEphoR574 rph-1
|
BD792 was made TcR with pAH14 then TcS Pho- derivatives were isolated.<ref name='PMID:9294451'/>
|
unpublished
|-
|
iii)
|
BW21652
|
F- LAM- rpoS396(Am) DEphoR574 DE(creABCD)154 rph-1
|
BW21597 was made TcR with pSK26 and then TcS Cre- derivatives were isolated. <ref name='PMID:8693022'/>
|
unpublished
|-
|
iv)
|
BW23186
|
F- LAM- rpoS396(Am) DEphoR574 DE(creABCD)154 DE(araBAD)567 rph-1
|
BW21652 was made TcR with pAH54 and then TcS Ara- derivatives were isolated. (<ref name='PMID:9495769'/>)
|
unpublished
|-
|
v)
|
BW23599
|
F- LAM- rpoS396(Am) rrnB3 DElacZ4787 proC::Tn5-132 DE(creABCD)154
DE(araBAD)567 rph-1
|
BW23186 was transduced to TcR Pro- Lac- Pho+ with P1''kc'' grown on BW22773<ref name='PMID:9495769'/>
|
unpublished
|-
|
vi)
|
BW23660
|
F- LAM- rpoS396(Am) rrnB3 DElacZ4787 DE(phoBR)580 DE(creABCD)154 DE(araBAD)567 rph-1
|
BW23599 was transduced to Pro+ Pho- with P1''kc'' grown on BW23316.
|
Haldimann et al. 1997<ref name='PMID:9294451'/>
|-
|
vii)
|
BW24200
|
F- LAM- rpoS396(Am) rrnB3 DElacZ4787 DE(phoBR)580 DE(creABCD)154
DE(araBAD)567 metF159(Am) zii-510::Tn10 rph-1
|
BW23660 was transduced to TcR Met- with P1''kc'' grown on JW383 (Haldimann et al., 1997)
|
unpublished
|-
|
viii)
|
BW24201
|
F- LAM- rpoS396(Am) rrnB3 DElacZ4787 DE(phoBR)580 DE(creABCD)154 DE(araBAD)567 DE(rhaBAD)568 rph-1
|
BW24200 was transduced to Met+ TcS Rha- with P1''kc'' grown on BW22875<ref name='PMID:9495769'/>
|
unpublished
|-
|
ix)
|
BW24310
|
F- LAM- rrnB3 DElacZ4787 DE(phoBR)580 DE(creABCD)154 DE(araBAD)567 DE(rhaBAD)568 cysC95::Tn10 rpoS::kan rph-1
|
BW24201 was transduced to TcR KmR with P1''kc'' grown on ZK1001<ref name='PMID:9495769'/>
|
Haldimann and Wanner, 2001<ref name='PMID:11591683'/>
|-
|
x)
|
BW24320a
|
F- LAM- rrnB3 DElacZ4787 DE(phoBR)580 DE(creABCD)154 DE(araBAD)567 DE(rhaBAD)568 rph-1
|
BW24310 was transduced to Cys+ KmS with P1''kc'' grown on MG1655 (Wanner and Boline, 1990)

aBW24320 and its descendants carry the same pseudorevertant rpoS(Q33) allele as MG1655 (Hayashi et al., 2005)
|
Haldimann and Wanner, 2001<ref name='PMID:11591683'/>
|-
|
xi)
|
BW24353
|
F- LAM- rrnB3 DElacZ4787 DE(phoBR)580 DE(zaa trpR creABCD arcA thr)104::Tn5-132 DE(araBAD)567 DE(rhaBAD)568 rph-1
|
BW24320 was transduced to TcR Thr- with P1''kc'' grown on BW12070 (Fisher et al., 1995)
|
unpublished
|-
|
xii)
|
BW24476
|
F- LAM- rrnB3 DElacZ4787 DE(phoBR)580 hsdR514 DE(araBAD)567 DE(rhaBAD)568 rph-1
|
BW24353 was transduced to Thr+ HsdR- with P1''kc'' grown on BW24447<ref name='PMID:10217500'/>
|
Stern et al., 1999<ref name='PMID:10217500'/>
|-
|
xiii)
|
BW25083
|
F- LAM- rrnB3 DElacZ4787 proC::Tn5-132 hsdR514 DE(araBAD)567 DE(rhaBAD)568 rph-1
|
BW24476 was transduced to TcR Pro- Pho+ with P1''kc'' grown on BW22773<ref name='PMID:9495769'/>
|
Haldimann and Wanner, 2001<ref name='PMID:11591683'/>
|-
|
xiv)
|
BW25113
|
F- LAM- rrnB3 DElacZ4787 hsdR514 DE(araBAD)567 DE(rhaBAD)568 rph-1
|
BW25083 was transduced to Pro+ with P1''kc'' grown on BW24321<ref name='PMID:11591683'/>
|
Lessard et al., 1998<ref name='PMID:9751644'/>; Datsenko and Wanner, 2000<ref name='PMID:10829079'/>

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==References==
{{RefHelp}}
<references/>

__NOTOC__
[[Category:Strains]]

[[Category:Strain:W1485]]