EcoliWiki - User contributions [en]

cysJ:Gene Product(s)

2010-05-03T23:32:56Z

Davidmigl: Table edited by Davidmigl via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|cysJ}}{{Tab|Gene|cysJ}}{{Tab On|Gene Product(s)|cysJ}}{{Tab|Expression|cysJ}}{{Tab|Evolution|cysJ}}{{Tab|On One Page|cysJ}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="N46aabcb53512c" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
CysJ
|-
!align=left {{table heading style}} |Synonyms
||
sulfite reductase, alpha subunit, flavoprotein<ref name='LIB:Riley_2006'/>, B2764<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CysJ<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
|-
!align=left {{table heading style}} |Product description
||
sulfite reductase flavoprotein subunit<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;

Component of [[:Category:Complex:SULFITE-REDUCT-CPLX|SULFITE-REDUCT-CPLX]]<ref name='LIB:EcoCyc10.6'/>

Sulfite reductase [NADPH] flavoprotein alpha-component; binds FMN and FAD<ref name='LIB:EcoGene'/>

Component of Molybdenum-cofactor dependent detoxification system for N-hydroxylated DNA/RNA bases<ref name='PMID:20118259'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.2 1.8.1.2]<ref name='LIB:Riley_2006'/>
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.8.1 1.6.8.1]<ref name='LIB:Riley_2006'/>

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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| id="O46aabcb6a0956" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0019344
|
cysteine biosynthetic process
|
GO_REF:0000002 GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR010199 SP_KW:KW-0198
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0000103
|
sulfate assimilation
|
GO_REF:0000002 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR010199 HAMAP:MF_01541
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0004783
|
sulfite reductase (NADPH) activity
|
GO_REF:0000002 GO_REF:0000003 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR010199 EC:1.8.1.2 HAMAP:MF_01541
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005506
|
iron ion binding
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001094
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0006810
|
transport
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0813
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0008652
|
amino acid biosynthetic process
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0028
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0009055
|
electron carrier activity
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001094
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0010181
|
FMN binding
|
GO_REF:0000002 GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001094 InterPro:IPR008254
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0016491
|
oxidoreductase activity
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001433 InterPro:IPR001709 InterPro:IPR003097 InterPro:IPR008254 SP_KW:KW-0560
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005515
|
protein binding
|
PMID:15690043
|
IPI: Inferred from Physical Interaction
|
UniProtKB:P75863
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005515
|
protein binding
|
PMID:16606699
|
IPI: Inferred from Physical Interaction
|
UniProtKB:P0A7J0
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|

|

|

|
C
|
Seeded from Riley et al 2006 <ref name='LIB:Riley_2006'/>.
|
required fields missing
|-
|

|
GO:0022900
|
electron transport chain
|
GO_REF:0000004
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0055114
|
oxidation reduction
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0560
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0006790
|
sulfur metabolic process
|

|

|

|
P
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
required fields missing

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|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| id="A46aabcbe86693" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
Subunits of [[:Category:Complex:SULFITE-REDUCT-CPLX|SULFITE-REDUCT-CPLX]]
|
could be indirect
|

|

|-
|
Protein
|
ycbX
|

|
<ref name='PMID:15690043'/><ref name='PMID:20118259'/>
|

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|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| id="U46a8538468d6e" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Source!!Notes

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<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="R46aabcc0e18f2" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=ALPHACOMP-MONOMER at EcoCyc]
<pre>MTTQVPPSAL LPLNPEQLAR LQAATTDLTP TQLAWVSGYF WGVLNQQPAA LAATPAPAAE
MPGITIISAS QTGNARRVAE ALRDDLLAAK LNVKLVNAGD YKFKQIASEK LLIVVTSTQG
EGEPPEEAVA LHKFLFSKKA PKLENTAFAV FSLGDSSYEF FCQSGKDFDS KLAELGGERL
LDRVDADVEY QAAASEWRAR VVDALKSRAP VAAPSQSVAT GAVNEIHTSP YSKDAPLVAS
LSVNQKITGR NSEKDVRHIE IDLGDSGMRY QPGDALGVWY QNDPALVKEL VELLWLKGDE
PVTVEGKTLP LNEALQWHFE LTVNTANIVE NYATLTRSET LLPLVGDKAK LQHYAATTPI
VDMVRFSPAQ LDAEALINLL RPLTPRLYSI ASSQAEVENE VHVTVGVVRY DVEGRARAGG
ASSFLADRVE EEGEVRVFIE HNDNFRLPAN PETPVIMIGP GTGIAPFRAF MQQRAADEAP
GKNWLFFGNP HFTEDFLYQV EWQRYVKDGV LTRIDLAWSR DQKEKVYVQD KLREQGAELW
RWINDGAHIY VCGDANRMAK DVEQALLEVI AEFGGMDTEA ADEFLSELRV ERRYQRDVY</pre>
|-
!align=left {{table heading style}} |Length
||
599
|-
!align=left {{table heading style}} |Mol. Wt
||
66.269 kDa
|-
!align=left {{table heading style}} |pI
||
4.8 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
85,830 - 86,080 (calc based on 17 Y, 11 W, and 2 C residues)

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|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| id="H46aabcc15d254" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Initiator Methionine
|
1
|
Removed
|
[http://www.uniprot.org/uniprot/P38038#section_features UniProt:P38038]
|

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|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="D46a853860e14c" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=cysJ
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)

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|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| id="U46aabcc227103" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25865.U46aabcc227103&page=25865&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| id="L46aabcc285a3b" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=ALPHACOMP-MONOMER EcoCyc:ALPHACOMP-MONOMER]
|

|-
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[[uniprot:P38038|UniProt:P38038]]
|

|-
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
|
[http://pfam.sanger.ac.uk/family?acc=PF00258 PFAM:PF00258]
|

|-
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_417244 RefSeq:NP_417244]
|

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|}


<protect></protect>
===Notes===

==Links==
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{| id="L46a85389aa00d" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
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|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:GO:0005737_!_cytoplasm]][[Category:GO:0006790_!_sulfur metabolic process]][[Category:Complex:SULFITE-REDUCT-CPLX]]

dnaA:Gene Product(s)

2010-05-03T23:26:38Z

Davidmigl: Table edited by Davidmigl via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|dnaA}}{{Tab|Gene|dnaA}}{{Tab On|Gene Product(s)|dnaA}}{{Tab|Expression|dnaA}}{{Tab|Evolution|dnaA}}{{Tab|On One Page|dnaA}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="T46aafcc991b86" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
DnaA
|-
!align=left {{table heading style}} |Synonyms
||
chromosomal replication initiator protein DnaA, DNA-binding transcriptional dual regulator<ref name='LIB:Riley_2006'/>, B3702<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DnaA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DNA biosynthesis; DnaA-ATP initiates chromosome replication; can be transcription regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
|-
!align=left {{table heading style}} |Product description
||
DnaA transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

DNA synthesis initiator and global transcription regulator; binds DNA at DnaA boxes, binds cardiolipin and other acidic phospholipids, binds ATP<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| id="W46aafccab4f9c" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0017111
|
nucleoside-triphosphatase activity
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR003593
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0043565
|
sequence-specific DNA binding
|
GO_REF:0000002 GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR010921 InterPro:IPR013159
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0006275
|
regulation of DNA replication
|
PMID:12068813
|
IMP: Inferred from Mutant Phenotype
|

|
P
|

|
complete
|-
|

|
GO:0006260
|
DNA replication
|
PMID:12068813
|
IMP: Inferred from Mutant Phenotype
|

|
P
|

|
complete
|-
|

|
GO:0006270
|
DNA replication initiation
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001957 InterPro:IPR013159 HAMAP:MF_00377
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0963
|
C
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000004 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001957 InterPro:IPR013159 SP_KW:KW-0067 HAMAP:MF_00377
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0000166
|
nucleotide binding
|
GO_REF:0000002 GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR003593 SP_KW:KW-0547
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0003677
|
DNA binding
|
GO_REF:0000002 GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001957 SP_KW:KW-0238
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0003688
|
DNA replication origin binding
|
GO_REF:0000002 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001957 HAMAP:MF_00377
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0006261
|
DNA-dependent DNA replication
|
PMID:2839499
|
IDA: Inferred from Direct Assay
|

|
P
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
complete
|-
|

|
GO:0006350
|
transcription
|

|

|

|
P
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
required fields missing
|-
|

|
GO:0016564
|
transcription repressor activity
|

|

|

|
F
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
required fields missing
|-
|

|
GO:0016563
|
transcription activator activity
|
PMID:16077105
|
IDA: Inferred from Direct Assay
|

|
F
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
complete

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|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| id="R46aafcdab0fb5" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
aspS 
|

|
PMID:15690043
|
Experiment(s):EBI-883418 
|-
|
Protein
|
cca 
|

|
PMID:15690043
|
Experiment(s):EBI-883418 
|-
|
Protein
|
dnaJ 
|

|
PMID:15690043
|
Experiment(s):EBI-883418, EBI-890702 
|-
|
Protein
|
lpdA 
|

|
PMID:15690043
|
Experiment(s):EBI-883418 
|-
|
Protein
|
nadE 
|

|
PMID:15690043
|
Experiment(s):EBI-883418 
|-
|
Protein
|
rplB 
|

|
PMID:15690043
|
Experiment(s):EBI-883418, EBI-890702 
|-
|
Protein
|
rplD 
|

|
PMID:15690043
|
Experiment(s):EBI-883418 
|-
|
Protein
|
rpsB 
|

|
PMID:15690043
|
Experiment(s):EBI-883418, EBI-890702 
|-
|
Protein
|
tufA 
|

|
PMID:15690043
|
Experiment(s):EBI-883418 
|-
|
Protein
|
rpsI 
|

|
PMID:16606699
|
Experiment(s):EBI-1146527 
|-
|
Protein
|
yfdS 
|

|
PMID:16606699
|
Experiment(s):EBI-1146527 
|-
|
Protein
|
yibL 
|

|
PMID:16606699
|
Experiment(s):EBI-1146527 
|-
|
Protein
|
rpsG 
|

|
PMID:16606699
|
Experiment(s):EBI-1146527 
|-
|
Protein
|
groL 
|

|
PMID:16606699
|
Experiment(s):EBI-1146527 
|-
|
Protein
|
dgt 
|

|
PMID:16606699
|
Experiment(s):EBI-1146527 
|-
|
Protein
|
creC 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplC 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplL 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplN 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplO 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplP 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplV 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplW 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplX 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpmB 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsC 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsE 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsG 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsI 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsJ 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsM 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsN 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsT 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
ynhG 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
Dps
|

|
PMID:18284581
|
Affinity chromatography and solid phase binding assay
|-
|
Protein
|
Hda
|

|
PMID:11483528
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.R46aafcdab0fb5&page=27983&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| id="N46a888b77216a" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Source!!Notes

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.N46a888b77216a&page=27983&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="Y46aafcdcdc9ab" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=PD03831 at EcoCyc]
<pre>MSLSLWQQCL ARLQDELPAT EFSMWIRPLQ AELSDNTLAL YAPNRFVLDW VRDKYLNNIN
GLLTSFCGAD APQLRFEVGT KPVTQTPQAA VTSNVAAPAQ VAQTQPQRAA PSTRSGWDNV
PAPAEPTYRS NVNVKHTFDN FVEGKSNQLA RAAARQVADN PGGAYNPLFL YGGTGLGKTH
LLHAVGNGIM ARKPNAKVVY MHSERFVQDM VKALQNNAIE EFKRYYRSVD ALLIDDIQFF
ANKERSQEEF FHTFNALLEG NQQIILTSDR YPKEINGVED RLKSRFGWGL TVAIEPPELE
TRVAILMKKA DENDIRLPGE VAFFIAKRLR SNVRELEGAL NRVIANANFT GRAITIDFVR
EALRDLLALQ EKLVTIDNIQ KTVAEYYKIK VADLLSKRRS RSVARPRQMA MALAKELTNH
SLPEIGDAFG GRDHTTVLHA CRKIEQLREE SHDIKEDFSN LIRTLSS</pre>
|-
!align=left {{table heading style}} |Length
||
467
|-
!align=left {{table heading style}} |Mol. Wt
||
52.551 kDa
|-
!align=left {{table heading style}} |pI
||
8.9 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
43,890 - 44,265 (calc based on 11 Y, 5 W, and 3 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.Y46aafcdcdc9ab&page=27983&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| id="I46aafcdd62c15" class=" tableEdit Product_motif_table dataTable"
|-
!|Type!!Residues!!Description!!Notes!!References

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.I46aafcdd62c15&page=27983&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="E46a888b91618b" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=dnaA
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.E46a888b91618b&page=27983&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| id="E46aafcde39678" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.E46aafcde39678&page=27983&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| id="S46aafcde9f98e" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=PD03831 EcoCyc:PD03831]
|

|-
|
[http://swissmodel.expasy.org/repository/ SwissModel] ([[SwissModel|EcoliWiki Page]])
|
[http://swissmodel.expasy.org/repository/smr.php?job=2&sptr_ac=P03004 SwissModel:P03004]
|

|-
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[[uniprot:P03004|UniProt:P03004]]
|

|-
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_418157 RefSeq:NP_418157]
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.S46aafcde9f98e&page=27983&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| id="V46a888bc95725" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.V46a888bc95725&page=27983&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:GO:0006261_!_DNA-dependent DNA replication]][[Category:GO:0005737_!_cytoplasm]][[Category:GO:0006350_!_transcription]][[Category:GO:0016564_!_transcription repressor activity]][[Category:GO:0016563_!_transcription activator activity]]

dnaA:Gene Product(s)

2010-05-03T23:23:39Z

Davidmigl: Table edited by Davidmigl via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|dnaA}}{{Tab|Gene|dnaA}}{{Tab On|Gene Product(s)|dnaA}}{{Tab|Expression|dnaA}}{{Tab|Evolution|dnaA}}{{Tab|On One Page|dnaA}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="T46aafcc991b86" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
DnaA
|-
!align=left {{table heading style}} |Synonyms
||
chromosomal replication initiator protein DnaA, DNA-binding transcriptional dual regulator<ref name='LIB:Riley_2006'/>, B3702<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DnaA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DNA biosynthesis; DnaA-ATP initiates chromosome replication; can be transcription regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
|-
!align=left {{table heading style}} |Product description
||
DnaA transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

DNA synthesis initiator and global transcription regulator; binds DNA at DnaA boxes, binds cardiolipin and other acidic phospholipids, binds ATP<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.T46aafcc991b86&page=27983&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| id="W46aafccab4f9c" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0017111
|
nucleoside-triphosphatase activity
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR003593
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0043565
|
sequence-specific DNA binding
|
GO_REF:0000002 GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR010921 InterPro:IPR013159
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0006275
|
regulation of DNA replication
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001957 InterPro:IPR013159 HAMAP:MF_00377
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0006260
|
DNA replication<input name="field[2]" type="hidden" value="DNA replication" />
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0235
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0006270
|
DNA replication initiation
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001957 InterPro:IPR013159 HAMAP:MF_00377
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0963
|
C
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000004 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001957 InterPro:IPR013159 SP_KW:KW-0067 HAMAP:MF_00377
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0000166
|
nucleotide binding
|
GO_REF:0000002 GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR003593 SP_KW:KW-0547
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0003677
|
DNA binding
|
GO_REF:0000002 GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001957 SP_KW:KW-0238
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0003688
|
DNA replication origin binding
|
GO_REF:0000002 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001957 HAMAP:MF_00377
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0006261
|
DNA-dependent DNA replication
|
PMID:2839499
|
IDA: Inferred from Direct Assay
|

|
P
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
complete
|-
|

|
GO:0006350
|
transcription
|

|

|

|
P
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
required fields missing
|-
|

|
GO:0016564
|
transcription repressor activity
|

|

|

|
F
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
required fields missing
|-
|

|
GO:0016563
|
transcription activator activity
|
PMID:16077105
|
IDA: Inferred from Direct Assay
|

|
F
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
complete

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.W46aafccab4f9c&page=27983&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table] || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| id="R46aafcdab0fb5" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
aspS 
|

|
PMID:15690043
|
Experiment(s):EBI-883418 
|-
|
Protein
|
cca 
|

|
PMID:15690043
|
Experiment(s):EBI-883418 
|-
|
Protein
|
dnaJ 
|

|
PMID:15690043
|
Experiment(s):EBI-883418, EBI-890702 
|-
|
Protein
|
lpdA 
|

|
PMID:15690043
|
Experiment(s):EBI-883418 
|-
|
Protein
|
nadE 
|

|
PMID:15690043
|
Experiment(s):EBI-883418 
|-
|
Protein
|
rplB 
|

|
PMID:15690043
|
Experiment(s):EBI-883418, EBI-890702 
|-
|
Protein
|
rplD 
|

|
PMID:15690043
|
Experiment(s):EBI-883418 
|-
|
Protein
|
rpsB 
|

|
PMID:15690043
|
Experiment(s):EBI-883418, EBI-890702 
|-
|
Protein
|
tufA 
|

|
PMID:15690043
|
Experiment(s):EBI-883418 
|-
|
Protein
|
rpsI 
|

|
PMID:16606699
|
Experiment(s):EBI-1146527 
|-
|
Protein
|
yfdS 
|

|
PMID:16606699
|
Experiment(s):EBI-1146527 
|-
|
Protein
|
yibL 
|

|
PMID:16606699
|
Experiment(s):EBI-1146527 
|-
|
Protein
|
rpsG 
|

|
PMID:16606699
|
Experiment(s):EBI-1146527 
|-
|
Protein
|
groL 
|

|
PMID:16606699
|
Experiment(s):EBI-1146527 
|-
|
Protein
|
dgt 
|

|
PMID:16606699
|
Experiment(s):EBI-1146527 
|-
|
Protein
|
creC 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplC 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplL 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplN 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplO 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplP 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplV 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplW 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplX 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpmB 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsC 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsE 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsG 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsI 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsJ 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsM 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsN 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsT 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
ynhG 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
Dps
|

|
PMID:18284581
|
Affinity chromatography and solid phase binding assay
|-
|
Protein
|
Hda
|

|
PMID:11483528
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.R46aafcdab0fb5&page=27983&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| id="N46a888b77216a" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Source!!Notes

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.N46a888b77216a&page=27983&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="Y46aafcdcdc9ab" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=PD03831 at EcoCyc]
<pre>MSLSLWQQCL ARLQDELPAT EFSMWIRPLQ AELSDNTLAL YAPNRFVLDW VRDKYLNNIN
GLLTSFCGAD APQLRFEVGT KPVTQTPQAA VTSNVAAPAQ VAQTQPQRAA PSTRSGWDNV
PAPAEPTYRS NVNVKHTFDN FVEGKSNQLA RAAARQVADN PGGAYNPLFL YGGTGLGKTH
LLHAVGNGIM ARKPNAKVVY MHSERFVQDM VKALQNNAIE EFKRYYRSVD ALLIDDIQFF
ANKERSQEEF FHTFNALLEG NQQIILTSDR YPKEINGVED RLKSRFGWGL TVAIEPPELE
TRVAILMKKA DENDIRLPGE VAFFIAKRLR SNVRELEGAL NRVIANANFT GRAITIDFVR
EALRDLLALQ EKLVTIDNIQ KTVAEYYKIK VADLLSKRRS RSVARPRQMA MALAKELTNH
SLPEIGDAFG GRDHTTVLHA CRKIEQLREE SHDIKEDFSN LIRTLSS</pre>
|-
!align=left {{table heading style}} |Length
||
467
|-
!align=left {{table heading style}} |Mol. Wt
||
52.551 kDa
|-
!align=left {{table heading style}} |pI
||
8.9 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
43,890 - 44,265 (calc based on 11 Y, 5 W, and 3 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.Y46aafcdcdc9ab&page=27983&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| id="I46aafcdd62c15" class=" tableEdit Product_motif_table dataTable"
|-
!|Type!!Residues!!Description!!Notes!!References

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.I46aafcdd62c15&page=27983&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="E46a888b91618b" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=dnaA
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.E46a888b91618b&page=27983&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| id="E46aafcde39678" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.E46aafcde39678&page=27983&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| id="S46aafcde9f98e" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=PD03831 EcoCyc:PD03831]
|

|-
|
[http://swissmodel.expasy.org/repository/ SwissModel] ([[SwissModel|EcoliWiki Page]])
|
[http://swissmodel.expasy.org/repository/smr.php?job=2&sptr_ac=P03004 SwissModel:P03004]
|

|-
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[[uniprot:P03004|UniProt:P03004]]
|

|-
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_418157 RefSeq:NP_418157]
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.S46aafcde9f98e&page=27983&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| id="V46a888bc95725" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.V46a888bc95725&page=27983&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:GO:0006261_!_DNA-dependent DNA replication]][[Category:GO:0005737_!_cytoplasm]][[Category:GO:0006350_!_transcription]][[Category:GO:0016564_!_transcription repressor activity]][[Category:GO:0016563_!_transcription activator activity]]

dnaA:Gene Product(s)

2010-05-03T23:21:26Z

Davidmigl: Table edited by Davidmigl via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|dnaA}}{{Tab|Gene|dnaA}}{{Tab On|Gene Product(s)|dnaA}}{{Tab|Expression|dnaA}}{{Tab|Evolution|dnaA}}{{Tab|On One Page|dnaA}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="T46aafcc991b86" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
DnaA
|-
!align=left {{table heading style}} |Synonyms
||
chromosomal replication initiator protein DnaA, DNA-binding transcriptional dual regulator<ref name='LIB:Riley_2006'/>, B3702<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DnaA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DNA biosynthesis; DnaA-ATP initiates chromosome replication; can be transcription regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
|-
!align=left {{table heading style}} |Product description
||
DnaA transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

DNA synthesis initiator and global transcription regulator; binds DNA at DnaA boxes, binds cardiolipin and other acidic phospholipids, binds ATP<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.T46aafcc991b86&page=27983&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| id="W46aafccab4f9c" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0017111
|
nucleoside-triphosphatase activity
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR003593
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0043565
|
sequence-specific DNA binding
|
GO_REF:0000002 GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR010921 InterPro:IPR013159
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0006275
|
regulation of DNA replication
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001957 InterPro:IPR013159 HAMAP:MF_00377
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0006260
|
DNA replication<input name="field[2]" type="hidden" value="DNA replication" />
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0235
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0006270
|
DNA replication initiation
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001957 InterPro:IPR013159 HAMAP:MF_00377
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0963
|
C
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000004 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001957 InterPro:IPR013159 SP_KW:KW-0067 HAMAP:MF_00377
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0000166
|
nucleotide binding
|
GO_REF:0000002 GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR003593 SP_KW:KW-0547
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0003677
|
DNA binding
|
GO_REF:0000002 GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001957 SP_KW:KW-0238
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0003688
|
DNA replication origin binding
|
GO_REF:0000002 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001957 HAMAP:MF_00377
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0006261
|
DNA-dependent DNA replication
|
PMID:2839499
|
IDA: Inferred from Direct Assay
|

|
P
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
complete
|-
|

|
GO:0006350
|
transcription
|

|

|

|
P
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
required fields missing
|-
|

|
GO:0016564
|
transcription repressor activity
|

|

|

|
F
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
required fields missing
|-
|

|
GO:0016563
|
transcription activator activity
|

|

|

|
F
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
required fields missing

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.W46aafccab4f9c&page=27983&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table] || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| id="R46aafcdab0fb5" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
aspS 
|

|
PMID:15690043
|
Experiment(s):EBI-883418 
|-
|
Protein
|
cca 
|

|
PMID:15690043
|
Experiment(s):EBI-883418 
|-
|
Protein
|
dnaJ 
|

|
PMID:15690043
|
Experiment(s):EBI-883418, EBI-890702 
|-
|
Protein
|
lpdA 
|

|
PMID:15690043
|
Experiment(s):EBI-883418 
|-
|
Protein
|
nadE 
|

|
PMID:15690043
|
Experiment(s):EBI-883418 
|-
|
Protein
|
rplB 
|

|
PMID:15690043
|
Experiment(s):EBI-883418, EBI-890702 
|-
|
Protein
|
rplD 
|

|
PMID:15690043
|
Experiment(s):EBI-883418 
|-
|
Protein
|
rpsB 
|

|
PMID:15690043
|
Experiment(s):EBI-883418, EBI-890702 
|-
|
Protein
|
tufA 
|

|
PMID:15690043
|
Experiment(s):EBI-883418 
|-
|
Protein
|
rpsI 
|

|
PMID:16606699
|
Experiment(s):EBI-1146527 
|-
|
Protein
|
yfdS 
|

|
PMID:16606699
|
Experiment(s):EBI-1146527 
|-
|
Protein
|
yibL 
|

|
PMID:16606699
|
Experiment(s):EBI-1146527 
|-
|
Protein
|
rpsG 
|

|
PMID:16606699
|
Experiment(s):EBI-1146527 
|-
|
Protein
|
groL 
|

|
PMID:16606699
|
Experiment(s):EBI-1146527 
|-
|
Protein
|
dgt 
|

|
PMID:16606699
|
Experiment(s):EBI-1146527 
|-
|
Protein
|
creC 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplC 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplL 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplN 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplO 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplP 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplV 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplW 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rplX 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpmB 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsC 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsE 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsG 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsI 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsJ 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsM 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsN 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
rpsT 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
ynhG 
|

|
PMID:15690043
|
Experiment(s):EBI-890702 
|-
|
Protein
|
Dps
|

|
PMID:18284581
|
Affinity chromatography and solid phase binding assay
|-
|
Protein
|
Hda
|

|
PMID:11483528
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.R46aafcdab0fb5&page=27983&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| id="N46a888b77216a" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Source!!Notes

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.N46a888b77216a&page=27983&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="Y46aafcdcdc9ab" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=PD03831 at EcoCyc]
<pre>MSLSLWQQCL ARLQDELPAT EFSMWIRPLQ AELSDNTLAL YAPNRFVLDW VRDKYLNNIN
GLLTSFCGAD APQLRFEVGT KPVTQTPQAA VTSNVAAPAQ VAQTQPQRAA PSTRSGWDNV
PAPAEPTYRS NVNVKHTFDN FVEGKSNQLA RAAARQVADN PGGAYNPLFL YGGTGLGKTH
LLHAVGNGIM ARKPNAKVVY MHSERFVQDM VKALQNNAIE EFKRYYRSVD ALLIDDIQFF
ANKERSQEEF FHTFNALLEG NQQIILTSDR YPKEINGVED RLKSRFGWGL TVAIEPPELE
TRVAILMKKA DENDIRLPGE VAFFIAKRLR SNVRELEGAL NRVIANANFT GRAITIDFVR
EALRDLLALQ EKLVTIDNIQ KTVAEYYKIK VADLLSKRRS RSVARPRQMA MALAKELTNH
SLPEIGDAFG GRDHTTVLHA CRKIEQLREE SHDIKEDFSN LIRTLSS</pre>
|-
!align=left {{table heading style}} |Length
||
467
|-
!align=left {{table heading style}} |Mol. Wt
||
52.551 kDa
|-
!align=left {{table heading style}} |pI
||
8.9 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
43,890 - 44,265 (calc based on 11 Y, 5 W, and 3 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.Y46aafcdcdc9ab&page=27983&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| id="I46aafcdd62c15" class=" tableEdit Product_motif_table dataTable"
|-
!|Type!!Residues!!Description!!Notes!!References

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.I46aafcdd62c15&page=27983&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="E46a888b91618b" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=dnaA
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.E46a888b91618b&page=27983&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| id="E46aafcde39678" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.E46aafcde39678&page=27983&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| id="S46aafcde9f98e" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=PD03831 EcoCyc:PD03831]
|

|-
|
[http://swissmodel.expasy.org/repository/ SwissModel] ([[SwissModel|EcoliWiki Page]])
|
[http://swissmodel.expasy.org/repository/smr.php?job=2&sptr_ac=P03004 SwissModel:P03004]
|

|-
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[[uniprot:P03004|UniProt:P03004]]
|

|-
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_418157 RefSeq:NP_418157]
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.S46aafcde9f98e&page=27983&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| id="V46a888bc95725" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.27983.V46a888bc95725&page=27983&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:GO:0006261_!_DNA-dependent DNA replication]][[Category:GO:0005737_!_cytoplasm]][[Category:GO:0006350_!_transcription]][[Category:GO:0016564_!_transcription repressor activity]][[Category:GO:0016563_!_transcription activator activity]]

User:Davidmigl

2010-05-03T18:18:41Z

Davidmigl: Created page with '-group 1 (i think) in cacao'

-group 1 (i think) in cacao

dapB:Gene Product(s)

2010-05-03T18:13:43Z

Davidmigl: Table edited by Davidmigl via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|dapB}}{{Tab|Gene|dapB}}{{Tab On|Gene Product(s)|dapB}}{{Tab|Expression|dapB}}{{Tab|Evolution|dapB}}{{Tab|On One Page|dapB}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="L46aa16887a5b9" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
DapB
|-
!align=left {{table heading style}} |Synonyms
||
dihydrodipicolinate reductase<ref name='LIB:Riley_2006'/>, B0031<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DapB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
|-
!align=left {{table heading style}} |Product description
||
DapB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;

Component of [[:Category:Complex:dihydrodipicolinate reductase|dihydrodipicolinate reductase]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

Dihydrodipicolinate reductase<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.26 1.3.1.26]<ref name='LIB:Riley_2006'/>

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19489.L46aa16887a5b9&page=19489&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| id="J46aa1689cb528" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0008652
|
cellular amino acid biosynthetic process
|
PMID:4151489
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0005737
|
cytoplasm
|
GO_REF:0000002 GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011770 SP_KW:KW-0963
|
C
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0019877
|
diaminopimelate biosynthetic process
|
PMID:4151489
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0016491
|
oxidoreductase activity
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0560
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0009085
|
lysine biosynthetic process
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0457
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0009089
|
lysine biosynthetic process via diaminopimelate
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000846 InterPro:IPR011770 HAMAP:MF_00102
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0008839
|
dihydrodipicolinate reductase activity
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000003 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000846 InterPro:IPR011770 EC:1.3.1.26 HAMAP:MF_00102
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0003824
|
catalytic activity
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR016040
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0005488
|
binding
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR016040
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0005829
|
cytosol
|
PMID:16858726
|
IDA: Inferred from Direct Assay
|

|
C
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0008152
|
metabolic process
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR016040
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0055114
|
oxidation reduction
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0560
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19489.J46aa1689cb528&page=19489&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table] || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| id="X46aa1693b04c9" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
Subunits of [[:Category:Complex:dihydrodipicolinate reductase|dihydrodipicolinate reductase]]
|
could be indirect
|

|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19489.X46aa1693b04c9&page=19489&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| id="Q46a72c6d79371" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Source!!Notes

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19489.Q46a72c6d79371&page=19489&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="O46aa1695c2792" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=DIHYDROPICRED-MONOMER at EcoCyc]
<pre>MHDANIRVAI AGAGGRMGRQ LIQAALALEG VQLGAALERE GSSLLGSDAG ELAGAGKTGV
TVQSSLDAVK DDFDVFIDFT RPEGTLNHLA FCRQHGKGMV IGTTGFDEAG KQAIRDAAAD
IAIVFAANFS VGVNVMLKLL EKAAKVMGDY TDIEIIEAHH RHKVDAPSGT ALAMGEAIAH
ALDKDLKDCA VYSREGHTGE RVPGTIGFAT VRAGDIVGEH TAMFADIGER LEITHKASSR
MTFANGAVRS ALWLSGKESG LFDMRDVLDL NNL</pre>
|-
!align=left {{table heading style}} |Length
||
273
|-
!align=left {{table heading style}} |Mol. Wt
||
28.756 kDa
|-
!align=left {{table heading style}} |pI
||
5.6 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
8,480 - 8,730 (calc based on 2 Y, 1 W, and 2 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19489.O46aa1695c2792&page=19489&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| id="P46aa169626113" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19489.P46aa169626113&page=19489&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="I46aa16966ea69" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=dapB
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19489.I46aa16966ea69&page=19489&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| id="Y46aa169967d71" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19489.Y46aa169967d71&page=19489&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| id="P46aa1699b0c91" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=DIHYDROPICRED-MONOMER EcoCyc:DIHYDROPICRED-MONOMER]
|

|-
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[[uniprot:P04036|UniProt:P04036]]
|

|-
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
|
[http://pfam.sanger.ac.uk/family?acc=PF01113 PFAM:PF01113]
|

|-
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_414572 RefSeq:NP_414572]
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19489.P46aa1699b0c91&page=19489&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| id="X46a72c75493ff" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19489.X46a72c75493ff&page=19489&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:GO:0005737_!_cytoplasm]][[Category:GO:0009089_!_lysine biosynthetic process via diaminopimelate]][[Category:Complex:dihydrodipicolinate reductase]][[Category:Products with structures in PDB]]

dcuS:Gene Product(s)

2010-05-03T17:55:12Z

Davidmigl: Table edited by Davidmigl via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|dcuS}}{{Tab|Gene|dcuS}}{{Tab On|Gene Product(s)|dcuS}}{{Tab|Expression|dcuS}}{{Tab|Evolution|dcuS}}{{Tab|On One Page|dcuS}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="A46ab1eb587604" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
DcuS
|-
!align=left {{table heading style}} |Synonyms
||
B4125<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YjdH<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
|-
!align=left {{table heading style}} |Product description
||
sensory histidine kinase in two-component regulatory system with DcuR, regulator of anaerobic fumarate respiration product<ref name='LIB:Riley_2006'/>

C4-dicarboxylate regulation of anaerobic fumurate respiratory system; two-component system sensory histidine kinase<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.28943.A46ab1eb587604&page=28943&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| id="F46ab1eb6b2cb0" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0000160
|
two-component signal transduction system (phosphorelay)
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-902
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0004673
|
protein histidine kinase activity
|
GO_REF:0000002 GO_REF:0000003
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR005467 EC:2.7.13.3
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0004871
|
signal transducer activity
|
PMID:12167640
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR003594
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0006355
|
regulation of transcription, DNA-dependent
|
PMID:14996819
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0007165
|
signal transduction
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000014
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0016020
|
membrane
|
GO_REF:0000004 GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0397 SP_KW:KW-0472
|
C
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
PMID:12907689
|
ISS: Inferred from Sequence or Structural Similarity
|
EcoliWiki:citA

|
C
|
NMR was used to determine the protein structure. It showed structural similarity to the CitA family of sensors.
|
complete
|-
|

|
GO:0016301
|
kinase activity
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0418
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0016310
|
phosphorylation
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004358
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0016740
|
transferase activity
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0808
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0016772
|
transferase activity, transferring phosphorus-containing groups
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004358
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0018106
|
peptidyl-histidine phosphorylation
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR005467
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0005515
|
protein binding
|
PMID:16606699
|
IPI: Inferred from Physical Interaction
|
UniProtKB:P0AC41
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0006464
|
protein modification process
|

|

|

|
P
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
required fields missing
|-
|

|
GO:0000155
|
two-component sensor activity
|
PMID:9973351
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
PMID:11803016
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete
|-
|

|
GO:0016485
|
protein processing
|

|

|

|
P
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
required fields missing
|-
|

|
GO:0009061
|
anaerobic respiration
|

|

|

|
P
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
required fields missing

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.28943.F46ab1eb6b2cb0&page=28943&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table] || || || || || || || ||
|}


<big>'''Interactions'''</big>


{{Product_interactions_help}}
{| id="Z46ab1ec31d507" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
sdhA 
|

|
PMID:16606699
|
Experiment(s):EBI-1147500 

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.28943.Z46ab1ec31d507&page=28943&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| id="D46ab1ec3e4d6a" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Source!!Notes
|-
|
plasma membrane
|
C-terminus localized in the cytoplasm with 2 predicted transmembrane domains
|
Daley et al. (2005) <ref name=PMID:15919996/>
|

|

|-
|
plasma membrane
|

|

|

|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.28943.D46ab1ec3e4d6a&page=28943&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="G46ab1ec5a8229" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=PHOSPHO-DCUS-MONOMER at EcoCyc]
<pre>MRHSLPYRML RKRPMKLSTT VILMVSAVLF SVLLVVHLIY FSQISDMTRD GLANKALAVA
RTLADSPEIR QGLQKKPQES GIQAIAEAVR KRNDLLFIVV TDMQSLRYSH PEAQRIGQPF
KGDDILKALN GEENVAINRG FLAQALRVFT PIYDENHKQI GVVAIGLELS RVTQQINDSR
WSIIWSVLFG MLVGLIGTCI LVKVLKKILF GLEPYEISTL FEQRQAMLQS IKEGVVAVDD
RGEVTLINDA AQELLNYRKS QDDEKLSTLS HSWSQVVDVS EVLRDGTPRR DEEITIKDRL
LLINTVPVRS NGVIIGAIST FRDKTEVRKL MQRLDGLVNY ADALRERSHE FMNKLHVILG
LLHLKSYKQL EDYILKTANN YQEEIGSLLG KIKSPVIAGF LISKINRATD LGHTLILNSE
SQLPDSGSED QVATLITTLG NLIENALEAL GPEPGGEISV TLHYRHGWLH CEVNDDGPGI
APDKIDHIFD KGVSTKGSER GVGLALVKQQ VENLGGSIAV ESEPGIFTQF FVQIPWDGER SNR</pre>
|-
!align=left {{table heading style}} |Length
||
543
|-
!align=left {{table heading style}} |Mol. Wt
||
60.552 kDa
|-
!align=left {{table heading style}} |pI
||
6.7 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
43,890 - 44,140 (calc based on 11 Y, 5 W, and 2 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.28943.G46ab1ec5a8229&page=28943&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big>
<table>
<tr align="left" valign="top">
<td>


{{Product_domains_motifs_help}}
{| id="Z46ab1ec62d962" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.28943.Z46ab1ec62d962&page=28943&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}


</td>
<td>


<motif_map/>
{{TMHMM Picture|dcuS}}
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="L46ab1ec691fda" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=dcuS
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.28943.L46ab1ec691fda&page=28943&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| id="W46ab1ec7048ec" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.28943.W46ab1ec7048ec&page=28943&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| id="Z46ab1ec76b225" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=DCUS-MONOMER EcoCyc:DCUS-MONOMER]
|

|-
|
[http://swissmodel.expasy.org/repository/ SwissModel] ([[SwissModel|EcoliWiki Page]])
|
[http://swissmodel.expasy.org/repository/smr.php?job=2&sptr_ac=P0AEC8 SwissModel:P0AEC8]
|

|-
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[[uniprot:P0AEC8|UniProt:P0AEC8]]
|

|-
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
|
[http://pfam.sanger.ac.uk/family?acc=PF00989 PFAM:PF00989]
|

|-
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_418549 RefSeq:NP_418549]
|

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| id="Y46ab1ed882104" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
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|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:Proteins]]
[[Category:GO:0006464_!_protein modification process]][[Category:GO:0016485_!_protein processing]][[Category:GO:0009061_!_anaerobic respiration]][[Category:Location:plasma membrane]][[Category:Products with structures in PDB]]

dapA:Gene Product(s)

2010-05-01T03:38:52Z

Davidmigl: Table edited by Davidmigl via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|dapA}}{{Tab|Gene|dapA}}{{Tab On|Gene Product(s)|dapA}}{{Tab|Expression|dapA}}{{Tab|Evolution|dapA}}{{Tab|On One Page|dapA}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="R46aaa9eee65cf" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
DapA
|-
!align=left {{table heading style}} |Synonyms
||
dihydrodipicolinate synthase<ref name='LIB:Riley_2006'/>, B2478<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DapA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
|-
!align=left {{table heading style}} |Product description
||
DapA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;

Component of [[:Category:Complex:dihydrodipicolinate synthase|dihydrodipicolinate synthase]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

Dihydrodipicolinate synthase<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.52 4.2.1.52]<ref name='LIB:Riley_2006'/>

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| id="X46aaa9f05c6a6" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0003824
|
catalytic activity
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR013785
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0963
|
C
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0008152
|
metabolic process
|
GO_REF:0000002 GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR002220 InterPro:IPR013785
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0008652
|
amino acid biosynthetic process
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0028
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0008840
|
dihydrodipicolinate synthase activity
|
PMID:4910051
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0009085
|
lysine biosynthetic process
|
GO_REF:0000004 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0457 HAMAP:MF_00418
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0016829
|
lyase activity
|
GO_REF:0000002 GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR002220 SP_KW:KW-0456
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0019877
|
diaminopimelate biosynthetic process
|
PMID:4910051
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete
|-
|

|
GO:0005829
|
cytosol
|
PMID:16858726
|
IDA: Inferred from Direct Assay
|

|
C
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0009089
|
lysine biosynthetic process via diaminopimelate
|

|

|

|
P
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
required fields missing

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|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| id="A46aaa9fb9a043" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
Subunits of [[:Category:Complex:dihydrodipicolinate synthase|dihydrodipicolinate synthase]]
|
could be indirect
|

|

|-
|
Protein
|
nadE 
|

|
PMID:16606699
|
Experiment(s):EBI-1142999 
|-
|
Protein
|
ycbB 
|

|
PMID:16606699
|
Experiment(s):EBI-1142999 

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|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| id="L46a84276de2f3" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Source!!Notes

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25206.L46a84276de2f3&page=25206&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="A46aaa9fdf18af" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=DIHYDRODIPICSYN-MONOMER at EcoCyc]
<pre>MFTGSIVAIV TPMDEKGNVC RASLKKLIDY HVASGTSAIV SVGTTGESAT LNHDEHADVV
MMTLDLADGR IPVIAGTGAN ATAEAISLTQ RFNDSGIVGC LTVTPYYNRP SQEGLYQHFK
AIAEHTDLPQ ILYNVPSRTG CDLLPETVGR LAKVKNIIGI KEATGNLTRV NQIKELVSDD
FVLLSGDDAS ALDFMQLGGH GVISVTANVA ARDMAQMCKL AAEGHFAEAR VINQRLMPLH
NKLFVEPNPI PVKWACKELG LVATDTLRLP MTPITDSGRE TVRAALKHAG LL</pre>
|-
!align=left {{table heading style}} |Length
||
292
|-
!align=left {{table heading style}} |Mol. Wt
||
31.269 kDa
|-
!align=left {{table heading style}} |pI
||
6.4 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
12,950 - 13,575 (calc based on 5 Y, 1 W, and 5 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25206.A46aaa9fdf18af&page=25206&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| id="F46aaa9fe6bf48" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25206.F46aaa9fe6bf48&page=25206&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="S46aaa9fec9357" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=dapA
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25206.S46aaa9fec9357&page=25206&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| id="G46aaaa019e6c8" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25206.G46aaaa019e6c8&page=25206&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| id="G46aaaa02081be" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=DIHYDRODIPICSYN-MONOMER EcoCyc:DIHYDRODIPICSYN-MONOMER]
|

|-
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[[uniprot:P0A6L2|UniProt:P0A6L2]]
|

|-
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
|
[http://pfam.sanger.ac.uk/family?acc=PF00701 PFAM:PF00701]
|

|-
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_416973 RefSeq:NP_416973]
|

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| id="X46a8427f5836b" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

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|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:GO:0005737_!_cytoplasm]][[Category:GO:0009089_!_lysine biosynthetic process via diaminopimelate]][[Category:Complex:dihydrodipicolinate synthase]][[Category:Products with structures in PDB]]

dapA:Gene Product(s)

2010-05-01T03:24:20Z

Davidmigl: Table edited by Davidmigl via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|dapA}}{{Tab|Gene|dapA}}{{Tab On|Gene Product(s)|dapA}}{{Tab|Expression|dapA}}{{Tab|Evolution|dapA}}{{Tab|On One Page|dapA}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="R46aaa9eee65cf" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
DapA
|-
!align=left {{table heading style}} |Synonyms
||
dihydrodipicolinate synthase<ref name='LIB:Riley_2006'/>, B2478<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DapA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
|-
!align=left {{table heading style}} |Product description
||
DapA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;

Component of [[:Category:Complex:dihydrodipicolinate synthase|dihydrodipicolinate synthase]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

Dihydrodipicolinate synthase<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.52 4.2.1.52]<ref name='LIB:Riley_2006'/>

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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| id="X46aaa9f05c6a6" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0003824
|
catalytic activity
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR013785
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0963
|
C
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0008152
|
metabolic process
|
GO_REF:0000002 GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR002220 InterPro:IPR013785
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0008652
|
amino acid biosynthetic process
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0028
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0008840
|
dihydrodipicolinate synthase activity
|
PMID:4910051
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0009085
|
lysine biosynthetic process
|
GO_REF:0000004 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0457 HAMAP:MF_00418
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0016829
|
lyase activity
|
GO_REF:0000002 GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR002220 SP_KW:KW-0456
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0019877
|
diaminopimelate biosynthetic process
|
GO_REF:0000002 GO_REF:0000004 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR005263 SP_KW:KW-0220 HAMAP:MF_00418
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005829
|
cytosol
|
PMID:16858726
|
IDA: Inferred from Direct Assay
|

|
C
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0009089
|
lysine biosynthetic process via diaminopimelate
|

|

|

|
P
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
required fields missing

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|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| id="A46aaa9fb9a043" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
Subunits of [[:Category:Complex:dihydrodipicolinate synthase|dihydrodipicolinate synthase]]
|
could be indirect
|

|

|-
|
Protein
|
nadE 
|

|
PMID:16606699
|
Experiment(s):EBI-1142999 
|-
|
Protein
|
ycbB 
|

|
PMID:16606699
|
Experiment(s):EBI-1142999 

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|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| id="L46a84276de2f3" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Source!!Notes

|- class="tableEdit_footer"
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|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="A46aaa9fdf18af" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=DIHYDRODIPICSYN-MONOMER at EcoCyc]
<pre>MFTGSIVAIV TPMDEKGNVC RASLKKLIDY HVASGTSAIV SVGTTGESAT LNHDEHADVV
MMTLDLADGR IPVIAGTGAN ATAEAISLTQ RFNDSGIVGC LTVTPYYNRP SQEGLYQHFK
AIAEHTDLPQ ILYNVPSRTG CDLLPETVGR LAKVKNIIGI KEATGNLTRV NQIKELVSDD
FVLLSGDDAS ALDFMQLGGH GVISVTANVA ARDMAQMCKL AAEGHFAEAR VINQRLMPLH
NKLFVEPNPI PVKWACKELG LVATDTLRLP MTPITDSGRE TVRAALKHAG LL</pre>
|-
!align=left {{table heading style}} |Length
||
292
|-
!align=left {{table heading style}} |Mol. Wt
||
31.269 kDa
|-
!align=left {{table heading style}} |pI
||
6.4 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
12,950 - 13,575 (calc based on 5 Y, 1 W, and 5 C residues)

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|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| id="F46aaa9fe6bf48" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References

|- class="tableEdit_footer"
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|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="S46aaa9fec9357" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=dapA
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)

|- class="tableEdit_footer"
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|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| id="G46aaaa019e6c8" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25206.G46aaaa019e6c8&page=25206&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| id="G46aaaa02081be" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=DIHYDRODIPICSYN-MONOMER EcoCyc:DIHYDRODIPICSYN-MONOMER]
|

|-
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[[uniprot:P0A6L2|UniProt:P0A6L2]]
|

|-
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
|
[http://pfam.sanger.ac.uk/family?acc=PF00701 PFAM:PF00701]
|

|-
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_416973 RefSeq:NP_416973]
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25206.G46aaaa02081be&page=25206&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| id="X46a8427f5836b" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25206.X46a8427f5836b&page=25206&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:GO:0005737_!_cytoplasm]][[Category:GO:0009089_!_lysine biosynthetic process via diaminopimelate]][[Category:Complex:dihydrodipicolinate synthase]][[Category:Products with structures in PDB]]

ddlB:Gene Product(s)

2010-05-01T02:59:27Z

Davidmigl: Table edited by Davidmigl via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|ddlB}}{{Tab|Gene|ddlB}}{{Tab On|Gene Product(s)|ddlB}}{{Tab|Expression|ddlB}}{{Tab|Evolution|ddlB}}{{Tab|On One Page|ddlB}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="N46aa1b406017e" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
DdlB
|-
!align=left {{table heading style}} |Synonyms
||
D-alanine:D-alanine ligase<ref name='LIB:Riley_2006'/>, B0092<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Ddl<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DdlB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
|-
!align=left {{table heading style}} |Product description
||
ddlB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;

Component of [[:Category:Complex:D-alanine-D-alanine ligase B|D-alanine-D-alanine ligase B]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

D-alanine:D-alanine ligase B, ADP-forming<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.4 6.3.2.4]<ref name='LIB:Riley_2006'/>

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| {{Prettytable}} id="R46aa1b41b7235" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0003824
|
catalytic activity
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011761 InterPro:IPR013816 InterPro:IPR013817
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011761 InterPro:IPR013816 InterPro:IPR013817
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0016874
|
ligase activity
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0436
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0009252
|
peptidoglycan biosynthetic process
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000004 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000291 InterPro:IPR005905 InterPro:IPR011095 InterPro:IPR011127 SP_KW:KW-0573 HAMAP:MF_00047
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005618
|
cell wall
|
PMID:9220001
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete
|-
|

|
GO:0005737
|
cytoplasm
|
GO_REF:0000002 GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR005905 SP_KW:KW-0963
|
C
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0007047
|
cell wall organization
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0961
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0008360
|
regulation of cell shape
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0133
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0008716
|
D-alanine-D-alanine ligase activity
|
PMID:8756703
|
IMP: Inferred from Mutant Phenotype
|

|
F
|

|
complete
|-
|

|
GO:0000166
|
nucleotide binding
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0547
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0000287
|
magnesium ion binding
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0460
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0030145
|
manganese ion binding
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0464
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0046872
|
metal ion binding
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0479
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0000910
|
cytokinesis
|

|

|

|
P
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
required fields missing
|-
|

|
GO:0008716
|
D-alanine-D-alanine ligase activity
|
PMID:1993184
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.R46aa1b41b7235&page=19669&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table] || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| id="C46aa1b4fd68aa" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
Subunits of [[:Category:Complex:D-alanine-D-alanine ligase B|D-alanine-D-alanine ligase B]]
|
could be indirect
|

|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.C46aa1b4fd68aa&page=19669&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| id="F46aa1b50dd8cb" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Source!!Notes
|-
|
cytoplasm
|

|

|
From EcoCyc<ref name='LIB:EcoCyc11.1'/>
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.F46aa1b50dd8cb&page=19669&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="S46aa1b524dfd4" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=DALADALALIGB-MONOMER at EcoCyc]
<pre>MTDKIAVLLG GTSAEREVSL NSGAAVLAGL REGGIDAYPV DPKEVDVTQL KSMGFQKVFI
ALHGRGGEDG TLQGMLELMG LPYTGSGVMA SALSMDKLRS KLLWQGAGLP VAPWVALTRA
EFEKGLSDKQ LAEISALGLP VIVKPSREGS SVGMSKVVAE NALQDALRLA FQHDEEVLIE
KWLSGPEFTV AILGEEILPS IRIQPSGTFY DYEAKYLSDE TQYFCPAGLE ASQEANLQAL
VLKAWTTLGC KGWGRIDVML DSDGQFYLLE ANTSPGMTSH SLVPMAARQA GMSFSQLVVR
ILELAD</pre>
|-
!align=left {{table heading style}} |Length
||
306
|-
!align=left {{table heading style}} |Mol. Wt
||
32.84 kDa
|-
!align=left {{table heading style}} |pI
||
4.6 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
37,930 - 38,180 (calc based on 7 Y, 5 W, and 2 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.S46aa1b524dfd4&page=19669&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| id="S46aa1b52a663a" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Initiator Methionine
|
1
|
Removed
|
[http://www.uniprot.org/uniprot/P07862#section_features UniProt:P07862]
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.S46aa1b52a663a&page=19669&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="E46aa1b52ef35b" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=ddlB
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.E46aa1b52ef35b&page=19669&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| id="J46aa1b54ab249" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.J46aa1b54ab249&page=19669&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| id="B46aa1b54f41b4" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=DALADALALIGB-MONOMER EcoCyc:DALADALALIGB-MONOMER]
|

|-
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[[uniprot:P07862|UniProt:P07862]]
|

|-
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
|
[http://pfam.sanger.ac.uk/family?acc=PF01820 PFAM:PF01820]
|

|-
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_414634 RefSeq:NP_414634]
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.B46aa1b54f41b4&page=19669&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| id="G46a730faa329a" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.G46a730faa329a&page=19669&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:GO:0005737_!_cytoplasm]][[Category:GO:0009252_!_peptidoglycan biosynthetic process]][[Category:GO:0000910_!_cytokinesis]][[Category:Complex:D-alanine-D-alanine ligase B]][[Category:Location:cytoplasm]][[Category:Products with structures in PDB]]

ddlB:Gene Product(s)

2010-05-01T02:57:17Z

Davidmigl: Table edited by Davidmigl via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|ddlB}}{{Tab|Gene|ddlB}}{{Tab On|Gene Product(s)|ddlB}}{{Tab|Expression|ddlB}}{{Tab|Evolution|ddlB}}{{Tab|On One Page|ddlB}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="N46aa1b406017e" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
DdlB
|-
!align=left {{table heading style}} |Synonyms
||
D-alanine:D-alanine ligase<ref name='LIB:Riley_2006'/>, B0092<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Ddl<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DdlB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
|-
!align=left {{table heading style}} |Product description
||
ddlB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;

Component of [[:Category:Complex:D-alanine-D-alanine ligase B|D-alanine-D-alanine ligase B]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

D-alanine:D-alanine ligase B, ADP-forming<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.4 6.3.2.4]<ref name='LIB:Riley_2006'/>

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.N46aa1b406017e&page=19669&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| {{Prettytable}} id="R46aa1b41b7235" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0003824
|
catalytic activity
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011761 InterPro:IPR013816 InterPro:IPR013817
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005524
|
ATP binding
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011761 InterPro:IPR013816 InterPro:IPR013817
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0016874
|
ligase activity
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0436
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0009252
|
peptidoglycan biosynthetic process
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000004 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000291 InterPro:IPR005905 InterPro:IPR011095 InterPro:IPR011127 SP_KW:KW-0573 HAMAP:MF_00047
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005618
|
cell wall
|
PMID:9220001
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete
|-
|

|
GO:0005737
|
cytoplasm
|
GO_REF:0000002 GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR005905 SP_KW:KW-0963
|
C
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0007047
|
cell wall organization
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0961
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0008360
|
regulation of cell shape
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0133
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0008716
|
D-alanine-D-alanine ligase activity
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000003 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000291 InterPro:IPR005905 InterPro:IPR011095 InterPro:IPR011127 EC:6.3.2.4 HAMAP:MF_00047
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0000166
|
nucleotide binding
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0547
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0000287
|
magnesium ion binding
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0460
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0030145
|
manganese ion binding
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0464
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0046872
|
metal ion binding
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0479
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0000910
|
cytokinesis
|

|

|

|
P
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
required fields missing
|-
|

|
GO:0008716
|
D-alanine-D-alanine ligase activity
|
PMID:1993184
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.R46aa1b41b7235&page=19669&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table] || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| id="C46aa1b4fd68aa" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
Subunits of [[:Category:Complex:D-alanine-D-alanine ligase B|D-alanine-D-alanine ligase B]]
|
could be indirect
|

|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.C46aa1b4fd68aa&page=19669&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| id="F46aa1b50dd8cb" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Source!!Notes
|-
|
cytoplasm
|

|

|
From EcoCyc<ref name='LIB:EcoCyc11.1'/>
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.F46aa1b50dd8cb&page=19669&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="S46aa1b524dfd4" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=DALADALALIGB-MONOMER at EcoCyc]
<pre>MTDKIAVLLG GTSAEREVSL NSGAAVLAGL REGGIDAYPV DPKEVDVTQL KSMGFQKVFI
ALHGRGGEDG TLQGMLELMG LPYTGSGVMA SALSMDKLRS KLLWQGAGLP VAPWVALTRA
EFEKGLSDKQ LAEISALGLP VIVKPSREGS SVGMSKVVAE NALQDALRLA FQHDEEVLIE
KWLSGPEFTV AILGEEILPS IRIQPSGTFY DYEAKYLSDE TQYFCPAGLE ASQEANLQAL
VLKAWTTLGC KGWGRIDVML DSDGQFYLLE ANTSPGMTSH SLVPMAARQA GMSFSQLVVR
ILELAD</pre>
|-
!align=left {{table heading style}} |Length
||
306
|-
!align=left {{table heading style}} |Mol. Wt
||
32.84 kDa
|-
!align=left {{table heading style}} |pI
||
4.6 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
37,930 - 38,180 (calc based on 7 Y, 5 W, and 2 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.S46aa1b524dfd4&page=19669&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| id="S46aa1b52a663a" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
|-
|
Initiator Methionine
|
1
|
Removed
|
[http://www.uniprot.org/uniprot/P07862#section_features UniProt:P07862]
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.S46aa1b52a663a&page=19669&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="E46aa1b52ef35b" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=ddlB
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.E46aa1b52ef35b&page=19669&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| id="J46aa1b54ab249" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.J46aa1b54ab249&page=19669&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| id="B46aa1b54f41b4" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=DALADALALIGB-MONOMER EcoCyc:DALADALALIGB-MONOMER]
|

|-
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[[uniprot:P07862|UniProt:P07862]]
|

|-
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
|
[http://pfam.sanger.ac.uk/family?acc=PF01820 PFAM:PF01820]
|

|-
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_414634 RefSeq:NP_414634]
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.B46aa1b54f41b4&page=19669&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| id="G46a730faa329a" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.19669.G46a730faa329a&page=19669&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:GO:0005737_!_cytoplasm]][[Category:GO:0009252_!_peptidoglycan biosynthetic process]][[Category:GO:0000910_!_cytokinesis]][[Category:Complex:D-alanine-D-alanine ligase B]][[Category:Location:cytoplasm]][[Category:Products with structures in PDB]]

cysN:Gene Product(s)

2010-05-01T02:46:49Z

Davidmigl: Table edited by Davidmigl via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|cysN}}{{Tab|Gene|cysN}}{{Tab On|Gene Product(s)|cysN}}{{Tab|Expression|cysN}}{{Tab|Evolution|cysN}}{{Tab|On One Page|cysN}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="O46aabc0c93985" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
CysN
|-
!align=left {{table heading style}} |Synonyms
||
sulfate adenylyltransferase, subunit 1<ref name='LIB:Riley_2006'/>, B2751<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CysN<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
|-
!align=left {{table heading style}} |Product description
||
CysN<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;

Component of [[:Category:Complex:SULFATE-ADENYLYLTRANS-CPLX|SULFATE-ADENYLYLTRANS-CPLX]]<ref name='LIB:EcoCyc10.6'/>; [[:Category:Complex:sulfate adenylyltransferase|sulfate adenylyltransferase]]<ref name='LIB:EcoCyc11.1'/>

Gtp subunit of ATP sulfurylase<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.4 2.7.7.4]<ref name='LIB:Riley_2006'/>

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.O46aabc0c93985&page=25835&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| id="O46aabc0e6a43a" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0000103
|
sulfate assimilation
|
GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_00062
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0000166
|
nucleotide binding
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0547
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0003924
|
GTPase activity
|
GO_REF:0000002
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0004781
|
sulfate adenylyltransferase (ATP) activity
|
PMID:2828368
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0005525
|
GTP binding
|
PMID:1730615
|
ISS: Inferred from Sequence or Structural Similarity
|
EcoliWiki:tufA
EcoliWiki:tufB

|
F
|
gene shows high sequence similarity to other gtp-binding genes.
|
complete
|-
|

|
GO:0008652
|
amino acid biosynthetic process
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0028
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0016740
|
transferase activity
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0808
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0016772
|
transferase activity, transferring phosphorus-containing groups
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011779
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0016779
|
nucleotidyltransferase activity
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0548
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0019344
|
cysteine biosynthetic process
|
GO_REF:0000004 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0198 HAMAP:MF_00062
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005515
|
protein binding
|
PMID:16606699
|
IPI: Inferred from Physical Interaction
|
UniProtKB:Q57261
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|

|

|

|
C
|
Seeded from Riley et al 2006 <ref name='LIB:Riley_2006'/>.
|
required fields missing
|-
|

|
GO:0006790
|
sulfur metabolic process
|
PMID:2828368
|
IMP: Inferred from Mutant Phenotype
|

|
P
|

|
complete

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.O46aabc0e6a43a&page=25835&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table] || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| id="T46aabc16515cb" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
Subunits of [[:Category:Complex:SULFATE-ADENYLYLTRANS-CPLX|SULFATE-ADENYLYLTRANS-CPLX]]
|
could be indirect
|
PMID:2828368
|

|-
|
Protein
|
truD 
|

|
PMID:16606699
|
Experiment(s):EBI-1143830 
|-
|
Protein
|
Subunits of [[:Category:Complex:sulfate adenylyltransferase|sulfate adenylyltransferase]]
|
could be indirect
|

|
PMID:2828368

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.T46aabc16515cb&page=25835&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| id="X46a852f32de0b" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Source!!Notes

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.X46a852f32de0b&page=25835&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="C46aabc1937063" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=CYSN-MONOMER at EcoCyc]
<pre>MNTALAQQIA NEGGVEAWMI AQQHKSLLRF LTCGSVDDGK STLIGRLLHD TRQIYEDQLS
SLHNDSKRHG TQGEKLDLAL LVDGLQAERE QGITIDVAYR YFSTEKRKFI IADTPGHEQY
TRNMATGAST CELAILLIDA RKGVLDQTRR HSFISTLLGI KHLVVAINKM DLVDYSEETF
TRIREDYLTF AGQLPGNLDI RFVPLSALEG DNVASQSESM PWYSGPTLLE VLETVEIQRV
VDAQPMRFPV QYVNRPNLDF RGYAGTLASG RVEVGQRVKV LPSGVESNVA RIVTFDGDRE
EAFAGEAITL VLTDEIDISR GDLLLAADEA LPAVQSASVD VVWMAEQPLS PGQSYDIKIA
GKKTRARVDG IRYQVDINNL TQREVENLPL NGIGLVDLTF DEPLVLDRYQ QNPVTGGLIF
IDRLSNVTVG AGMVHEPVSQ ATAAPSEFSA FELELNALVR RHFPHWGARD LLGDK</pre>
|-
!align=left {{table heading style}} |Length
||
475
|-
!align=left {{table heading style}} |Mol. Wt
||
52.558 kDa
|-
!align=left {{table heading style}} |pI
||
4.8 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
39,880 - 40,130 (calc based on 12 Y, 4 W, and 2 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.C46aabc1937063&page=25835&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| id="S46aabc19a6be8" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.S46aabc19a6be8&page=25835&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="Y46a852f4d276e" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=cysN
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)

|- class="tableEdit_footer"
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|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| id="A46aabc1a70806" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.A46aabc1a70806&page=25835&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| id="D46aabc1acf17e" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=CYSN-MONOMER EcoCyc:CYSN-MONOMER]
|

|-
|
[http://swissmodel.expasy.org/repository/ SwissModel] ([[SwissModel|EcoliWiki Page]])
|
[http://swissmodel.expasy.org/repository/smr.php?job=2&sptr_ac=P23845 SwissModel:P23845]
|

|-
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[[uniprot:P23845|UniProt:P23845]]
|

|-
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
|
[http://pfam.sanger.ac.uk/family?acc=PF00009 PFAM:PF00009]
|

|-
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_417231 RefSeq:NP_417231]
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.D46aabc1acf17e&page=25835&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| id="Z46a852f931ba8" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.Z46a852f931ba8&page=25835&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:GO:0005737_!_cytoplasm]][[Category:GO:0006790_!_sulfur metabolic process]][[Category:Complex:SULFATE-ADENYLYLTRANS-CPLX]][[Category:Complex:sulfate adenylyltransferase]]

cysN:Gene Product(s)

2010-05-01T02:39:38Z

Davidmigl: Table edited by Davidmigl via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|cysN}}{{Tab|Gene|cysN}}{{Tab On|Gene Product(s)|cysN}}{{Tab|Expression|cysN}}{{Tab|Evolution|cysN}}{{Tab|On One Page|cysN}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="O46aabc0c93985" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
CysN
|-
!align=left {{table heading style}} |Synonyms
||
sulfate adenylyltransferase, subunit 1<ref name='LIB:Riley_2006'/>, B2751<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CysN<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
|-
!align=left {{table heading style}} |Product description
||
CysN<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;

Component of [[:Category:Complex:SULFATE-ADENYLYLTRANS-CPLX|SULFATE-ADENYLYLTRANS-CPLX]]<ref name='LIB:EcoCyc10.6'/>; [[:Category:Complex:sulfate adenylyltransferase|sulfate adenylyltransferase]]<ref name='LIB:EcoCyc11.1'/>

Gtp subunit of ATP sulfurylase<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.4 2.7.7.4]<ref name='LIB:Riley_2006'/>

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.O46aabc0c93985&page=25835&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| id="O46aabc0e6a43a" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0000103
|
sulfate assimilation
|
GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_00062
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0000166
|
nucleotide binding
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0547
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0003924
|
GTPase activity
|
GO_REF:0000002
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0004781
|
sulfate adenylyltransferase (ATP) activity
|
PMID:2828368
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0005525
|
GTP binding
|
PMID:1730615
|
ISS: Inferred from Sequence or Structural Similarity
|
EcoliWiki:tufA
EcoliWiki:tufB

|
F
|
gene shows high sequence similarity to other gtp-binding genes.
|
complete
|-
|

|
GO:0008652
|
amino acid biosynthetic process
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0028
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0016740
|
transferase activity
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0808
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0016772
|
transferase activity, transferring phosphorus-containing groups
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011779
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0016779
|
nucleotidyltransferase activity
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0548
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0019344
|
cysteine biosynthetic process
|
GO_REF:0000004 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0198 HAMAP:MF_00062
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005515
|
protein binding
|
PMID:16606699
|
IPI: Inferred from Physical Interaction
|
UniProtKB:Q57261
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|

|

|

|
C
|
Seeded from Riley et al 2006 <ref name='LIB:Riley_2006'/>.
|
required fields missing
|-
|

|
GO:0006790
|
sulfur metabolic process
|
PMID:2828368
|
IMP: Inferred from Mutant Phenotype
|

|
P
|

|
complete

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.O46aabc0e6a43a&page=25835&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table] || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| id="T46aabc16515cb" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
Subunits of [[:Category:Complex:SULFATE-ADENYLYLTRANS-CPLX|SULFATE-ADENYLYLTRANS-CPLX]]
|
could be indirect
|

|

|-
|
Protein
|
truD 
|

|
PMID:16606699
|
Experiment(s):EBI-1143830 
|-
|
Protein
|
Subunits of [[:Category:Complex:sulfate adenylyltransferase|sulfate adenylyltransferase]]
|
could be indirect
|

|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.T46aabc16515cb&page=25835&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| id="X46a852f32de0b" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Source!!Notes

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.X46a852f32de0b&page=25835&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="C46aabc1937063" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=CYSN-MONOMER at EcoCyc]
<pre>MNTALAQQIA NEGGVEAWMI AQQHKSLLRF LTCGSVDDGK STLIGRLLHD TRQIYEDQLS
SLHNDSKRHG TQGEKLDLAL LVDGLQAERE QGITIDVAYR YFSTEKRKFI IADTPGHEQY
TRNMATGAST CELAILLIDA RKGVLDQTRR HSFISTLLGI KHLVVAINKM DLVDYSEETF
TRIREDYLTF AGQLPGNLDI RFVPLSALEG DNVASQSESM PWYSGPTLLE VLETVEIQRV
VDAQPMRFPV QYVNRPNLDF RGYAGTLASG RVEVGQRVKV LPSGVESNVA RIVTFDGDRE
EAFAGEAITL VLTDEIDISR GDLLLAADEA LPAVQSASVD VVWMAEQPLS PGQSYDIKIA
GKKTRARVDG IRYQVDINNL TQREVENLPL NGIGLVDLTF DEPLVLDRYQ QNPVTGGLIF
IDRLSNVTVG AGMVHEPVSQ ATAAPSEFSA FELELNALVR RHFPHWGARD LLGDK</pre>
|-
!align=left {{table heading style}} |Length
||
475
|-
!align=left {{table heading style}} |Mol. Wt
||
52.558 kDa
|-
!align=left {{table heading style}} |pI
||
4.8 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
39,880 - 40,130 (calc based on 12 Y, 4 W, and 2 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.C46aabc1937063&page=25835&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| id="S46aabc19a6be8" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.S46aabc19a6be8&page=25835&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="Y46a852f4d276e" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=cysN
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.Y46a852f4d276e&page=25835&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| id="A46aabc1a70806" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.A46aabc1a70806&page=25835&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| id="D46aabc1acf17e" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=CYSN-MONOMER EcoCyc:CYSN-MONOMER]
|

|-
|
[http://swissmodel.expasy.org/repository/ SwissModel] ([[SwissModel|EcoliWiki Page]])
|
[http://swissmodel.expasy.org/repository/smr.php?job=2&sptr_ac=P23845 SwissModel:P23845]
|

|-
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[[uniprot:P23845|UniProt:P23845]]
|

|-
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
|
[http://pfam.sanger.ac.uk/family?acc=PF00009 PFAM:PF00009]
|

|-
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_417231 RefSeq:NP_417231]
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.D46aabc1acf17e&page=25835&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| id="Z46a852f931ba8" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.Z46a852f931ba8&page=25835&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:GO:0005737_!_cytoplasm]][[Category:GO:0006790_!_sulfur metabolic process]][[Category:Complex:SULFATE-ADENYLYLTRANS-CPLX]][[Category:Complex:sulfate adenylyltransferase]]

cysN:Gene Product(s)

2010-05-01T02:32:36Z

Davidmigl: Table edited by Davidmigl via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|cysN}}{{Tab|Gene|cysN}}{{Tab On|Gene Product(s)|cysN}}{{Tab|Expression|cysN}}{{Tab|Evolution|cysN}}{{Tab|On One Page|cysN}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="O46aabc0c93985" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
CysN
|-
!align=left {{table heading style}} |Synonyms
||
sulfate adenylyltransferase, subunit 1<ref name='LIB:Riley_2006'/>, B2751<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CysN<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
|-
!align=left {{table heading style}} |Product description
||
CysN<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;

Component of [[:Category:Complex:SULFATE-ADENYLYLTRANS-CPLX|SULFATE-ADENYLYLTRANS-CPLX]]<ref name='LIB:EcoCyc10.6'/>; [[:Category:Complex:sulfate adenylyltransferase|sulfate adenylyltransferase]]<ref name='LIB:EcoCyc11.1'/>

Gtp subunit of ATP sulfurylase<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.4 2.7.7.4]<ref name='LIB:Riley_2006'/>

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.O46aabc0c93985&page=25835&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| id="O46aabc0e6a43a" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0000103
|
sulfate assimilation
|
GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_00062
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0000166
|
nucleotide binding
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0547
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0003924
|
GTPase activity
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000795
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0004781
|
sulfate adenylyltransferase (ATP) activity
|
PMID:2828368
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0005525
|
GTP binding
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000004 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000795 InterPro:IPR004161 SP_KW:KW-0342 HAMAP:MF_00062
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0008652
|
amino acid biosynthetic process
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0028
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0016740
|
transferase activity
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0808
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0016772
|
transferase activity, transferring phosphorus-containing groups
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011779
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0016779
|
nucleotidyltransferase activity
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0548
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0019344
|
cysteine biosynthetic process
|
GO_REF:0000004 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0198 HAMAP:MF_00062
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005515
|
protein binding
|
PMID:16606699
|
IPI: Inferred from Physical Interaction
|
UniProtKB:Q57261
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|

|

|

|
C
|
Seeded from Riley et al 2006 <ref name='LIB:Riley_2006'/>.
|
required fields missing
|-
|

|
GO:0006790
|
sulfur metabolic process
|
PMID:2828368
|
IMP: Inferred from Mutant Phenotype
|

|
P
|

|
complete

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.O46aabc0e6a43a&page=25835&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table] || || || || || || || ||
|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| id="T46aabc16515cb" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
Subunits of [[:Category:Complex:SULFATE-ADENYLYLTRANS-CPLX|SULFATE-ADENYLYLTRANS-CPLX]]
|
could be indirect
|

|

|-
|
Protein
|
truD 
|

|
PMID:16606699
|
Experiment(s):EBI-1143830 
|-
|
Protein
|
Subunits of [[:Category:Complex:sulfate adenylyltransferase|sulfate adenylyltransferase]]
|
could be indirect
|

|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.T46aabc16515cb&page=25835&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| id="X46a852f32de0b" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Source!!Notes

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.X46a852f32de0b&page=25835&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="C46aabc1937063" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=CYSN-MONOMER at EcoCyc]
<pre>MNTALAQQIA NEGGVEAWMI AQQHKSLLRF LTCGSVDDGK STLIGRLLHD TRQIYEDQLS
SLHNDSKRHG TQGEKLDLAL LVDGLQAERE QGITIDVAYR YFSTEKRKFI IADTPGHEQY
TRNMATGAST CELAILLIDA RKGVLDQTRR HSFISTLLGI KHLVVAINKM DLVDYSEETF
TRIREDYLTF AGQLPGNLDI RFVPLSALEG DNVASQSESM PWYSGPTLLE VLETVEIQRV
VDAQPMRFPV QYVNRPNLDF RGYAGTLASG RVEVGQRVKV LPSGVESNVA RIVTFDGDRE
EAFAGEAITL VLTDEIDISR GDLLLAADEA LPAVQSASVD VVWMAEQPLS PGQSYDIKIA
GKKTRARVDG IRYQVDINNL TQREVENLPL NGIGLVDLTF DEPLVLDRYQ QNPVTGGLIF
IDRLSNVTVG AGMVHEPVSQ ATAAPSEFSA FELELNALVR RHFPHWGARD LLGDK</pre>
|-
!align=left {{table heading style}} |Length
||
475
|-
!align=left {{table heading style}} |Mol. Wt
||
52.558 kDa
|-
!align=left {{table heading style}} |pI
||
4.8 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
39,880 - 40,130 (calc based on 12 Y, 4 W, and 2 C residues)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.C46aabc1937063&page=25835&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| id="S46aabc19a6be8" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.S46aabc19a6be8&page=25835&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || || ||
|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="Y46a852f4d276e" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=cysN
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.Y46a852f4d276e&page=25835&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| id="A46aabc1a70806" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.A46aabc1a70806&page=25835&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| id="D46aabc1acf17e" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=CYSN-MONOMER EcoCyc:CYSN-MONOMER]
|

|-
|
[http://swissmodel.expasy.org/repository/ SwissModel] ([[SwissModel|EcoliWiki Page]])
|
[http://swissmodel.expasy.org/repository/smr.php?job=2&sptr_ac=P23845 SwissModel:P23845]
|

|-
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[[uniprot:P23845|UniProt:P23845]]
|

|-
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
|
[http://pfam.sanger.ac.uk/family?acc=PF00009 PFAM:PF00009]
|

|-
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_417231 RefSeq:NP_417231]
|

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.D46aabc1acf17e&page=25835&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| id="Z46a852f931ba8" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25835.Z46a852f931ba8&page=25835&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:GO:0005737_!_cytoplasm]][[Category:GO:0006790_!_sulfur metabolic process]][[Category:Complex:SULFATE-ADENYLYLTRANS-CPLX]][[Category:Complex:sulfate adenylyltransferase]]

cysN:Gene Product(s)

2010-05-01T02:26:07Z

Davidmigl: Table edited by Davidmigl via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|cysN}}{{Tab|Gene|cysN}}{{Tab On|Gene Product(s)|cysN}}{{Tab|Expression|cysN}}{{Tab|Evolution|cysN}}{{Tab|On One Page|cysN}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="O46aabc0c93985" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
CysN
|-
!align=left {{table heading style}} |Synonyms
||
sulfate adenylyltransferase, subunit 1<ref name='LIB:Riley_2006'/>, B2751<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CysN<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
|-
!align=left {{table heading style}} |Product description
||
CysN<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;

Component of [[:Category:Complex:SULFATE-ADENYLYLTRANS-CPLX|SULFATE-ADENYLYLTRANS-CPLX]]<ref name='LIB:EcoCyc10.6'/>; [[:Category:Complex:sulfate adenylyltransferase|sulfate adenylyltransferase]]<ref name='LIB:EcoCyc11.1'/>

Gtp subunit of ATP sulfurylase<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.4 2.7.7.4]<ref name='LIB:Riley_2006'/>

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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| id="O46aabc0e6a43a" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0000103
|
sulfate assimilation
|
GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_00062
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0000166
|
nucleotide binding
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0547
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0003924
|
GTPase activity
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000795
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0004781
|
sulfate adenylyltransferase (ATP) activity
|
PMID:2828368
|
IDA: Inferred from Direct Assay
|

|
F
|

|
complete
|-
|

|
GO:0005525
|
GTP binding
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000004 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR000795 InterPro:IPR004161 SP_KW:KW-0342 HAMAP:MF_00062
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0008652
|
amino acid biosynthetic process
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0028
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0016740
|
transferase activity
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0808
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0016772
|
transferase activity, transferring phosphorus-containing groups
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011779
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0016779
|
nucleotidyltransferase activity
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0548
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0019344
|
cysteine biosynthetic process
|
GO_REF:0000004 GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0198 HAMAP:MF_00062
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005515
|
protein binding
|
PMID:16606699
|
IPI: Inferred from Physical Interaction
|
UniProtKB:Q57261
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0005737
|
cytoplasm
|

|

|

|
C
|
Seeded from Riley et al 2006 <ref name='LIB:Riley_2006'/>.
|
required fields missing
|-
|

|
GO:0006790
|
sulfur metabolic process
|

|

|

|
P
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
required fields missing

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|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| id="T46aabc16515cb" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
|
Protein
|
Subunits of [[:Category:Complex:SULFATE-ADENYLYLTRANS-CPLX|SULFATE-ADENYLYLTRANS-CPLX]]
|
could be indirect
|

|

|-
|
Protein
|
truD 
|

|
PMID:16606699
|
Experiment(s):EBI-1143830 
|-
|
Protein
|
Subunits of [[:Category:Complex:sulfate adenylyltransferase|sulfate adenylyltransferase]]
|
could be indirect
|

|

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|}


</protect>
===Notes===

==Localization==

{{Product_localization_help}}
{| id="X46a852f32de0b" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Source!!Notes

|- class="tableEdit_footer"
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|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="C46aabc1937063" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=CYSN-MONOMER at EcoCyc]
<pre>MNTALAQQIA NEGGVEAWMI AQQHKSLLRF LTCGSVDDGK STLIGRLLHD TRQIYEDQLS
SLHNDSKRHG TQGEKLDLAL LVDGLQAERE QGITIDVAYR YFSTEKRKFI IADTPGHEQY
TRNMATGAST CELAILLIDA RKGVLDQTRR HSFISTLLGI KHLVVAINKM DLVDYSEETF
TRIREDYLTF AGQLPGNLDI RFVPLSALEG DNVASQSESM PWYSGPTLLE VLETVEIQRV
VDAQPMRFPV QYVNRPNLDF RGYAGTLASG RVEVGQRVKV LPSGVESNVA RIVTFDGDRE
EAFAGEAITL VLTDEIDISR GDLLLAADEA LPAVQSASVD VVWMAEQPLS PGQSYDIKIA
GKKTRARVDG IRYQVDINNL TQREVENLPL NGIGLVDLTF DEPLVLDRYQ QNPVTGGLIF
IDRLSNVTVG AGMVHEPVSQ ATAAPSEFSA FELELNALVR RHFPHWGARD LLGDK</pre>
|-
!align=left {{table heading style}} |Length
||
475
|-
!align=left {{table heading style}} |Mol. Wt
||
52.558 kDa
|-
!align=left {{table heading style}} |pI
||
4.8 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
39,880 - 40,130 (calc based on 12 Y, 4 W, and 2 C residues)

|- class="tableEdit_footer"
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|}


<big>'''Domains/Motifs/Modification Sites'''</big><table>
<tr align="left" valign="top">
<td>
{{Product_domains_motifs_help}}
{| id="S46aabc19a6be8" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References

|- class="tableEdit_footer"
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|}
</td>
<td>


<motif_map/>
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="Y46a852f4d276e" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=cysN
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)

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|}


</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| id="A46aabc1a70806" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

|- class="tableEdit_footer"
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|}


<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| id="D46aabc1acf17e" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=CYSN-MONOMER EcoCyc:CYSN-MONOMER]
|

|-
|
[http://swissmodel.expasy.org/repository/ SwissModel] ([[SwissModel|EcoliWiki Page]])
|
[http://swissmodel.expasy.org/repository/smr.php?job=2&sptr_ac=P23845 SwissModel:P23845]
|

|-
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[[uniprot:P23845|UniProt:P23845]]
|

|-
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
|
[http://pfam.sanger.ac.uk/family?acc=PF00009 PFAM:PF00009]
|

|-
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_417231 RefSeq:NP_417231]
|

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|}


<protect></protect>
===Notes===

==Links==
{{BacktoTop}}


{| id="Z46a852f931ba8" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

|- class="tableEdit_footer"
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|}


<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:GO:0005737_!_cytoplasm]][[Category:GO:0006790_!_sulfur metabolic process]][[Category:Complex:SULFATE-ADENYLYLTRANS-CPLX]][[Category:Complex:sulfate adenylyltransferase]]

proP:Gene Product(s)

2010-04-16T01:43:40Z

Davidmigl: Table edited by Davidmigl via TableEdit

{{#css:Suppresslinks.css}}<css>{{:Suppresslinks.css}}</css>
<noinclude>{{TabsTop}}
{{Tab|Quickview|proP}}{{Tab|Gene|proP}}{{Tab On|Gene Product(s)|proP}}{{Tab|Expression|proP}}{{Tab|Evolution|proP}}{{Tab|On One Page|proP}}{{TabsBottom}}
{|
|-
|{{Sub}}[[#Nomenclature |Nomenclature]]
|{{Sub}}[[#Function |Function]]
|{{Sub}}[[#Interactions |Interactions]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Accessions in Other Databases |Accessions]]
|{{Sub}}[[#Links |Links]]
|{{Sub}}[[#References| References]]
|{{Sub}}[[Talk:{{PAGENAMEE}}| Suggestions]]
|}
</noinclude>
==Nomenclature==

{{Product_nomenclature_help}}
{| id="T46ab1d4bc96e0" class=" tableEdit Product_nomenclature_table"

|-
!align=left {{table heading style}} |Standard name
||
ProP
|-
!align=left {{table heading style}} |Synonyms
||
proline/glycine betaine transporter<ref name='LIB:Riley_2006'/>, B4111<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ProP<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
|-
!align=left {{table heading style}} |Product description
||
ProP proline/betaine MFS transporter<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>

Proline/betaine permease, minor; osmosensor/osmoregulator<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||

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|}


<protect></protect>
===Notes===

==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big> 
{{Product_GO_help}}
{| id="G46ab1d4ce7da9" class=" tableEdit GO_table_product dataTable"
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|

|
GO:0006810
|
transport
|
PMID:6355059
|
IGI: Inferred from Genetic Interaction
|

|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0015292
|
uniporter activity
|
PMID:15205426
|
IGI: Inferred from Genetic Interaction
|

|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0015295
|
solute:hydrogen symporter activity
|
PMID:3049595
|
IGI: Inferred from Genetic Interaction
|

|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0042538
|
hyperosmotic salinity response
|
PMID:3082857
|
IGI: Inferred from Genetic Interaction
|

|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
PMID:10026245
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete
|-
|

|
GO:0016020
|
membrane
|
GO_REF:0000002 GO_REF:0000004 GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR005829 SP_KW:KW-0397 SP_KW:KW-0472
|
C
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0006810
|
transport
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004736 InterPro:IPR005828 InterPro:IPR005829 InterPro:IPR007114 SP_KW:KW-0813
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0006561
|
proline biosynthetic process
|

|

|

|
P
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
|
required fields missing
|-
|

|
GO:0005886
|
plasma membrane
|
PMID:10026245
|
IDA: Inferred from Direct Assay
|

|
C
|

|
complete
|-
|

|
GO:0015293
|
symporter activity
|
GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0769
|
F
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0016021
|
integral to membrane
|
GO_REF:0000002 GO_REF:0000002 GO_REF:0000002 GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR004736 InterPro:IPR005828 InterPro:IPR007114 SP_KW:KW-0812
|
C
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
complete
|-
|

|
GO:0005886
|
plasma membrane
|
GO_REF:0000004 GO_REF:0000004 GO_REF:0000023
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0997 SP_KW:KW-1003 SP_SL:SL-0037
|
C
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|

|
GO:0006865
|
amino acid transport
|
PMID:10026245
|
IDA: Inferred from Direct Assay
|

|
P
|

|
complete

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|}


<big>'''Interactions'''</big>

{{Product_interactions_help}}
{| id="B46ab1d597e0a3" class=" tableEdit Product_interactions_table dataTable"
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence

|- class="tableEdit_footer"
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|}


</protect>
===Notes===
Proline transporter activity is sensitive to the osmolality of the growth medium. Activation and polar localization depend on cardiolipin content of the membrane.

==Localization==

{{Product_localization_help}}
{| id="G46ab1d5a53983" class=" tableEdit Product_localization_table"
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Source!!Notes
|-
|
plasma membrane
|
C-terminus localized in the cytoplasm with 12 predicted transmembrane domains
|
Daley et al. (2005) <ref name=PMID:15919996/>
|

|

|-
|
plasma membrane
|

|

|
From EcoCyc<ref name='LIB:EcoCyc11.1'/>
|

|-
|
Pole
|

|
Fluorescence microscopy
PMID:17504273
PMID:18326496

|

|

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|}


<protect></protect>

===Notes===

==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<big>'''Physical Properties'''</big>

{{Product_physical_properties_help}}
{| id="L46ab1d5c0c35e" class=" tableEdit Product_phys_prop_table"

|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=PROP-MONOMER at EcoCyc]
<pre>MLKRKKVKPI TLRDVTIIDD GKLRKAITAA SLGNAMEWFD FGVYGFVAYA LGKVFFPGAD
PSVQMVAALA TFSVPFLIRP LGGLFFGMLG DKYGRQKILA ITIVIMSIST FCIGLIPSYD
TIGIWAPILL LICKMAQGFS VGGEYTGASI FVAEYSPDRK RGFMGSWLDF GSIAGFVLGA
GVVVLISTIV GEANFLDWGW RIPFFIALPL GIIGLYLRHA LEETPAFQQH VDKLEQGDRE
GLQDGPKVSF KEIATKYWRS LLTCIGLVIA TNVTYYMLLT YMPSYLSHNL HYSEDHGVLI
IIAIMIGMLF VQPVMGLLSD RFGRRPFVLL GSVALFVLAI PAFILINSNV IGLIFAGLLM
LAVILNCFTG VMASTLPAMF PTHIRYSALA AAFNISVLVA GLTPTLAAWL VESSQNLMMP
AYYLMVVAVV GLITGVTMKE TANRPLKGAT PAASDIQEAK EILVEHYDNI EQKIDDIDHE
IADLQAKRTR LVQQHPRIDE</pre>
|-
!align=left {{table heading style}} |Length
||
500
|-
!align=left {{table heading style}} |Mol. Wt
||
54.848 kDa
|-
!align=left {{table heading style}} |pI
||
7.2 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
63,830 - 64,330 (calc based on 17 Y, 7 W, and 4 C residues)

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<big>'''Domains/Motifs/Modification Sites'''</big>
<table>
<tr align="left" valign="top">
<td>


{{Product_domains_motifs_help}}
{| id="F46ab1d5c86f58" class=" tableEdit Product_motif_table dataTable"
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References

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</td>
<td>


<motif_map/>
{{TMHMM Picture|proP}}
</td>
</tr>
</table>

<table><tr valign='top'><td>
<big>'''Structure'''</big> 

{{Product_structure_help}}
{| id="K46ab1d5cefa5d" class=" tableEdit Product_structure_table"

|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=proP
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)

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</td><td></protect>
==== Structure figures ====

<protect>
</td><tr><table></protect>
===Notes===

==Gene Product Resources==
{{BacktoTop}}

{{Product_resources_help}}
{| id="C46ab1d5d6687e" class=" tableEdit Product_resource_table"
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference

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<protect></protect>
===Notes===

==Accessions in Other Databases==
{{BacktoTop}}

{{Gene_accessions_help}}
{| id="T46ab1d5dccde5" class=" tableEdit Gene_accessions_table"
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=PROP-MONOMER EcoCyc:PROP-MONOMER]
|

|-
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[[uniprot:P0C0L7|UniProt:P0C0L7]]
|

|-
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
|
[http://pfam.sanger.ac.uk/family?acc=PF00083 PFAM:PF00083]
|

|-
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_418535 RefSeq:NP_418535]
|

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<protect></protect>
===Notes===

==Links==
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{| id="D46ab1d6176ff3" class=" tableEdit Links_table"
|- {{table_heading_style}}
!|Name!!URL!!Comments

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<noinclude>
==References==
{{BacktoTop}}
{{RefHelp}}
<references />
__NOTOC__
===Categories===
{{BacktoTop}}
[[Category:Proteins]]
[[Category:GO:0006561_!_proline biosynthetic process]][[Category:GO:0015292_!_uniporter activity]][[Category:GO:0006970_!_response to osmotic stress]][[Category:Location:plasma membrane]]