EcoliWiki - User contributions [en]

PMID:4571524

2012-11-09T15:34:35Z

117.207.78.68: Fill PMID: Page!

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{| id="F509d228b328be" class=" tableEdit PMID_info_table"

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!align=left |Citation
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'''Iwakura, Y, Ishihama, A and Yura, T''' (1973) RNA polymerase mutants of Escherichia coli. Streptolydigin resistance and its relation to rifampicin resistance.''Mol. Gen. Genet.'' '''121''':181-96
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!align=left |Abstract
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No abstract in PubMed
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!align=left |Links
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=4571524 PubMed]

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!align=left |Keywords
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Anti-Bacterial Agents; DNA-Directed RNA Polymerases; Drug Resistance, Microbial; Escherichia coli; Genetics, Microbial; Mutation; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Pyrans; Pyrroles; RNA; Rifampin

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==Significance {{HelpIcon|Help:Literature}} ==
{{LitSignificance}}

== Useful Materials and Methods {{HelpIcon|Help:Literature}}==
{{LitMaterials}}

==Annotations {{HelpIcon|Help:Literature}}==
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{| id="H509d228b4448a" class=" tableEdit GO_table_reference dataTable"
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!|Gene product!!Qualifier!!GO ID!!GO term name!!Evidence Code!!with/from!!Aspect!!Notes!!Status

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==EcoliWiki Links {{HelpIcon|Help:Literature}} ==
{{LitLinks}}

==See also==

==References==
{{RefHelp}}
<references/>

PMID:4571524

2012-11-09T15:34:35Z

117.207.78.68: New PMID: Page!

PMID:4879326

2012-11-09T15:34:33Z

117.207.78.68: Fill PMID: Page!

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{| id="K509d2288cbf5d" class=" tableEdit PMID_info_table"

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!align=left |Citation
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'''Ezekiel, DH and Hutchins, JE''' (1968) Mutations affecting RNA polymerase associated with rifampicin resistance in Escherichia coli.''Nature'' '''220''':276-7
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!align=left |Abstract
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No abstract in PubMed
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!align=left |Links
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=4879326 PubMed]

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!align=left |Keywords
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Anti-Bacterial Agents; Carbon Isotopes; Drug Resistance, Microbial; Escherichia coli; Genetic Code; Genetics, Microbial; Hot Temperature; Mutation; Protein Denaturation; RNA Nucleotidyltransferases; RNA, Bacterial; Rifampin; Tritium; Uracil Nucleotides

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==Significance {{HelpIcon|Help:Literature}} ==
{{LitSignificance}}

== Useful Materials and Methods {{HelpIcon|Help:Literature}}==
{{LitMaterials}}

==Annotations {{HelpIcon|Help:Literature}}==
<protect>

{| id="Z509d2288e706d" class=" tableEdit GO_table_reference dataTable"
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!|Gene product!!Qualifier!!GO ID!!GO term name!!Evidence Code!!with/from!!Aspect!!Notes!!Status

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|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=d41d8cd98f00b204e9800998ecf8427e.182732.Z509d2288e706d&page=182732&pagename={{FULLPAGENAMEE}}&type=0&template=GO_table_reference edit table] || || || || || || || ||
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</protect>

==EcoliWiki Links {{HelpIcon|Help:Literature}} ==
{{LitLinks}}

==See also==

==References==
{{RefHelp}}
<references/>

PMID:4879326

2012-11-09T15:34:32Z

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PMID:3050121

2012-11-09T15:34:32Z

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{| id="I509d22875e1ad" class=" tableEdit PMID_info_table"

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'''Jin, DJ and Gross, CA''' (1988) Mapping and sequencing of mutations in the Escherichia coli rpoB gene that lead to rifampicin resistance.''J. Mol. Biol.'' '''202''':45-58
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!align=left |Abstract
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Rifampicin is an antibiotic that inhibits the function of RNA polymerase in eubacteria. Mutations affecting the beta subunit of RNA polymerase can confer resistance to rifampicin. A large number of rifampicin-resistant (hereafter called Rifr) mutants have been isolated in Escherichia coli to probe the involvement of RNA polymerase in a variety of physiological processes. We have undertaken a comprehensive analysis of Rifr mutations to identify their structural and functional effects on RNA polymerase. Forty-two Rifr isolates with a variety of phenotypes were mapped to defined intervals within the rpoB gene using a set of deletions of the rpoB gene. The mutations were sequenced. Seventeen mutational alterations affecting 14 amino acid residues were identified. These alleles are located in three distinct clusters in the center of the rpoB gene. We discuss the implications of our results with regards to the structure of the rifampicin binding site.
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!align=left |Links
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3050121 PubMed]

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!align=left |Keywords
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Base Sequence; Chromosome Mapping; DNA-Directed RNA Polymerases; Drug Resistance, Microbial; Escherichia coli; Genes, Bacterial; Molecular Sequence Data; Mutation; Plasmids; Rifampin

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==Significance {{HelpIcon|Help:Literature}} ==
{{LitSignificance}}

== Useful Materials and Methods {{HelpIcon|Help:Literature}}==
{{LitMaterials}}

==Annotations {{HelpIcon|Help:Literature}}==
<protect>

{| id="F509d2287cb8a9" class=" tableEdit GO_table_reference dataTable"
|- {{table heading style}}
!|Gene product!!Qualifier!!GO ID!!GO term name!!Evidence Code!!with/from!!Aspect!!Notes!!Status

|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=d41d8cd98f00b204e9800998ecf8427e.182731.F509d2287cb8a9&page=182731&pagename={{FULLPAGENAMEE}}&type=0&template=GO_table_reference edit table] || || || || || || || ||
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</protect>

==EcoliWiki Links {{HelpIcon|Help:Literature}} ==
{{LitLinks}}

==See also==

==References==
{{RefHelp}}
<references/>

PMID:3050121

2012-11-09T15:34:31Z

117.207.78.68: New PMID: Page!