phoA:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
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| Standard Name |
phoA |
|---|---|
| Gene Synonym(s) |
ECK0378, b0383, JW0374, psiA[1], psiA |
| Product Desc. |
Component of alkaline phosphatase[2][3] Alkaline phosphatase, periplasmic; binds Zn(II); dimeric[4] |
| Product Synonyms(s) |
bacterial alkaline phosphatase[1], B0383[2][1], PsiA[2][1], PhoA[2][1] , ECK0378, JW0374, psiA, b0383 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
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| edit table |
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Notes
Arg22 is removed from the mature enzyme by Iap to form isozyme 3. Isozyme 2 is a heterodimer of isozymes 1 and 3 subunits. PhoA requires the reducing environment of the periplasm and DsbA for activity; cysteine bonds C190-C200 and C308-C358 are needed. PhoA fusions are used to indicate periplasmic location of hybrid proteins.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
