hipA:Quickview

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Standard Name

hipA

Gene Synonym(s)

ECK1500, b1507, JW1500[1], JW1500

Product Desc.

HipA Polypeptide[2]; serine kinase HipA[3];

Component of HipB transcriptional repressor[3]

Toxin, growth inhibition blocked by continuous HipB synthesis;; probable role in cell division[4]

Product Synonyms(s)

regulator with hipB[1], B1507[2][1], HipA[2][1] , ECK1500, JW1500, b1507

Function from GO

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Knock-Out Phenotype
Regulation/Expression

transcription unit(s): hipBA[2]

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Notes

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HipA serine protein kinase autophosphorylates Ser150 and this activity is essential for persister formation (Correia, 2006). HipA binds and phosphorylates TufA/TufB (Schumacher, 2009).[4]



References

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  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.