gcvA:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
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Standard Name

gcvA

Gene Synonym(s)

ECK2803, b2808, JW2779[1], JW2779

Product Desc.

GcvA transcriptional dual regulator[2][3]

Glycine-responsive activator of gcv operon; acts as repressor in absence of glycine, probably antagonized by Crp; repression function enhanced by exogenous purine addition; repressor function requires GcvR interaction[4]

Product Synonyms(s)

DNA-binding transcriptional dual regulator[1], B2808[2][1], GcvA[2][1], positive regulator of gcv operon[2][1], ECK2803, JW2779, b2808

Function from GO

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Knock-Out Phenotype
Regulation/Expression

transcription unit(s): gcvA[2], OP00233

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Notes

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Glycine co-activator binds to GcvR and disrupts GcvA-GcvR interaction.[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.